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The goal of Schistosomiasis is to provide the reader with insights into the active research and programs currently related to schistosomiasis, and to use these insights as a way to project forward into the next 10-15 years of work on this disease, spanning the spectrum from research to public health interventions. A secondary goal of this volume is to initiate conversations among those working across the research-to-control spectrum on schistosomiasis about the future of their field, and by doing so lead to constructive efforts to identify and address the most critical questions and challenges related to schistosomiasis. The book covers four main areas: schistosome phylogenetics, gene expression, and the overall genome, including information on exciting new tools for addressing questions that have long been inaccessible to schistosomologists; the host-schistosome interaction at the larval to adult worm interface and addresses aspects important for vaccine development as well as how differential gene expression as detected by DNA microarrays may be utilized to develop tools for detection and control of infection or pathology; the development of the host immune response to eggs, granuloma formation and factors affecting the development and regulation of immunopathology; and the public health concerns associated with schistosomiasis, including morbidity control, host genetics, treatment and proposals for improved partnerships. The volume concludes with a chapter addressing the schisms that sometimes exist along the spectrum from basic research programs to the implementation of control schemes, and a proposal to make these differences benefit patients and researchers rather than succumb to base temptations to compete for resources to no one’s benefit. Like many of the diseases featured in the World Class Parasites series, the prospects for dramatic advances in schistosomiasis coincide with a seemingly shrinking pool of both human and material resources. The most meaningful progress will occur as the laboratory better understands the needs in the field and the field better understands the capabilities of the laboratory.
Schistosomiasis. --- Distomatosis. --- Distomiasis --- Trematode infections --- Helminthiasis --- Bilharziasis --- Bilharziosis --- Katayama disease --- Snail fever --- Distomatosis --- Morphology (Animals). --- Emerging infectious diseases. --- Animal Anatomy / Morphology / Histology. --- Infectious Diseases. --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Animal morphology --- Animals --- Body form in animals --- Zoology --- Morphology --- Animal anatomy. --- Infectious diseases. --- Animal anatomy --- Biology --- Physiology --- Anatomy
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It is with great pleasure that we introduce the first volume of Birkhäuser Advances in Infectious Diseases. This book series focuses on relevant and trending topics in microbiology and infectious diseases with emphasis on emerging pathogens and related diseases. This interdisciplinary series presents latest advances and new approaches in molecular biology as well as insights into human and veterinary clinical medicine. Furthermore, matters in epidemiology, disease management, hygiene and prevention of infectious diseases are discussed. Emerging or novel pathogens are a grand challenge in medical science. Therefore, we focused the first volume of this series on the outbreak of SARS. The advent of SARS is a threat for people around the globe. Our modern technologies in communication and mobility have figuratively transformed the world into a village. This traffic, however, represents a new opportunity to spread diseases, particularly such of infectious nature from tiny villages throughout the entire world. In-depth knowledge of a novel pathogen's characteristics will help to manage or event prevent pandemias.
SARS (Disease) --- Coronavirus infections. --- Coronaviruses. --- Common cold viruses --- Coronaviridae --- Nidoviruses --- Coronavirus diseases --- Virus diseases --- Acute respiratory syndrome, Severe --- Respiratory syndrome, Severe acute --- Severe acute respiratory syndrome --- Coronavirus infections --- Respiratory infections --- Syndromes --- Emerging infectious diseases. --- Microbiology. --- Infectious Diseases. --- Medical Microbiology. --- Microbial biology --- Biology --- Microorganisms --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Infectious diseases. --- Medical microbiology.
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La protesi totale di ginocchio è divenuta oggi intervento di routine nelle nostre sale operatorie. La diffusione di tale intervento non deve però far dimenticare quanto sia complessa questa chirurgia articolare, che si avvale anche di sofisticati ausili informatici. Basandosi sulla loro lunga e collaudata esperienza, gli autori di questo quarto volume della collana forniscono al lettore un’aggiornata rassegna dello stato dell’arte.
Knee --- Arthroplasty. --- Surgery. --- Joints --- Surgery, Plastic --- Excision of knee --- Surgery --- Orthopedics. --- Emerging infectious diseases. --- Surgical oncology. --- Orthopedic surgery. --- Rheumatology. --- Infectious Diseases. --- Surgical Oncology. --- Surgical Orthopedics. --- Internal medicine --- Connective tissues --- Operative orthopedics --- Orthopedics --- Surgery, Operative --- Cancer --- Oncologic surgery --- Oncological surgery --- Surgical oncology --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Orthopaedics --- Orthopedia --- Diseases --- Excision --- Treatment --- Infectious diseases.
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Recently, modern laboratory techniques have been applied with great success to DNA viruses, an important viral class that shares basic survival strategies and mechanisms of pathogenesis, and also provides model systems for the investigation of basic biological processes. In DNA Viruses: Methods and Protocols, a panel of expert academic and biomedical researchers describe in detail the innovative methods they have developed to manipulate DNA viruses and characterize their varied biological properties. The authors emphasize techniques for viral detection and genetics, but also include methods for structure determination, gene expression, replication, pathogenesis, complex cellular models, recombinant genetics, and computational/systems approaches. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Wide-ranging and highly practical, DNA Viruses: Methods and Protocols will stimulate new directions in research virology with its novel strategies for engineering viral vectors in gene therapy, and its advanced approaches for detecting viruses in human disease.
Emerging infectious diseases. --- Medical virology. --- Biochemistry. --- Infectious Diseases. --- Virology. --- Biochemistry, general. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Medical microbiology --- Virology --- Virus diseases --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Composition
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Summarizes projects aiming to detect risks of biological toxins, superantigens and the modeling of their effects. This volume presents the potential risks, detection and prevention of chronic and zoonotic infections in addition to interaction of human pathogens affecting biological risks. It also includes experimental vaccines and therapeutics.
Emerging infectious diseases --- Bioterrorism --- Biological weapons --- Communicable diseases --- Infection --- Contagion and contagious diseases --- Contagious diseases --- Infectious diseases --- Microbial diseases in human beings --- Zymotic diseases --- Diseases --- Epidemics --- Bacteriological weapons --- Biological warfare agents --- Bioweapons --- Weapons of mass destruction --- Biosecurity --- Bio-terrorism --- Biological terrorism --- Terrorism --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Prevention --- Law and legislation
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Fungal immunology, an expanding field of research, studies the interaction between fungi and the immune system. Modulated immunity as well as evasive mechanisms played by fungi all contribute to the chronicity and reoccurrence of fungal infections. Hypersensitivity to various fungal elements plays a major role in the pathogenesis of many diseases. This book will serve as a comprehensive review of all known immune mechanisms for common medically important fungal pathogens. Its novelty lies in the organization: Rather than chapters devoted to specific fungi, chapters are organized by organ system. All other texts in the field, which are now quite old, are arranged according to specific fungi. Organization by body system rather than fungi is important because one particular fungus can have a different effect on defense mechanisms in different parts of the body.
Mycoses --- Pathogenic fungi. --- Immunological aspects. --- Fungi, Pathogenic --- Fungi --- Pathogenic microorganisms --- Medical mycology --- Fungal diseases --- Fungal infections --- Fungous diseases --- Mycosis --- Mycotic diseases --- Mycotic infections --- Immunology. --- Microbiology. --- Emerging infectious diseases. --- Thoracic surgery. --- Medical Microbiology. --- Infectious Diseases. --- Thoracic Surgery. --- Microbial biology --- Biology --- Microorganisms --- Immunobiology --- Life sciences --- Serology --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Thoracic surgery --- Thoracic surgeons --- Medical microbiology. --- Infectious diseases.
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2004 marks the 100th anniversary of the first description of the autoimmune disease paroxysmal cold hemoglobinuria, a rare hemolytic disorder, by Julius Donath and Karl Landsteiner. After a century of research, the list of autoimmune diseases has become impressive. With a prevalence of approximately 5% of the world-wide population, these chronic, debilitating conditions affect almost every major organ of the body and, for reasons that remain unclear, are much more prevalent in woman than in men. Despite our rapidly expanding knowledge of the cellular and molecular pathways that govern a normal immune response, deciphering the precise etiology of autoimmune diseases remains an important challenge. Over the last few years, our understanding of the pathogenesis of autoimmune diseases has improved rapidly, leading to the emergence of elegant immunointervention strategies. Molecular Autoimmunity illustrates how cutting-edge research is continuing to advance our understanding of autoimmune disease mechanisms and identifies novel therapeutic targets that provide a hope for effective future treatments. This volume contains a selected number of exciting advances in unraveling autoimmune reactions, and the resulting new armory of experimental immunotherapies that may lead to new ways of controlling autoimmune reactions.
Autoimmunity. --- Autoimmune diseases. --- Autoimmunologic diseases --- Autoimmunity --- Immunologic diseases --- Autoallergy --- Immunity --- Autoantibodies --- Immunology. --- Emerging infectious diseases. --- Medical virology. --- Microbiology. --- Pathology. --- Pharmacy. --- Infectious Diseases. --- Virology. --- Chemistry --- Medicine --- Drugs --- Materia medica --- Pharmacology --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine, Preventive --- Microbial biology --- Biology --- Microorganisms --- Medical microbiology --- Virology --- Virus diseases --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Immunobiology --- Life sciences --- Serology --- Infectious diseases. --- Microbiology
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Orthopoxviruses Pathogenic for Humans covers those viruses capable of causing disease in man, including monkeypox, smallpox, cowpox, and vaccinia. The coverage of each virus is comprehensive, covering the biology, molecular biology, and ecology of the virus as well as the clinical and epidemiological aspects of these viruses in humans and animals. In addition, this volume highlights developments in genetic engineering that are paving the way for potential therapeutic treatments of these viruses.
Orthopoxviruses. --- Poxviruses. --- Poxviruses --- Poxviridae --- DNA viruses --- Medical virology. --- Immunology. --- Microbiology. --- Emerging infectious diseases. --- Epidemiology. --- Virology. --- Infectious Diseases. --- Public Health. --- Diseases --- Public health --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Microbial biology --- Biology --- Microorganisms --- Immunobiology --- Life sciences --- Serology --- Medical microbiology --- Virology --- Virus diseases --- Infectious diseases. --- Public health. --- Community health --- Health services --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Social hygiene --- Health --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation --- Microbiology
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This book is an excellent, up-to-date reference on a relatively young area of research in which virology, cellular biology and molecular pathogenesis govern the principles of coinvestigation. Thus, the book will be of great interest to virologists, molecular immunologists and biologists, and biochemists but also to clinical pharmacologists in the long-term search for new antiviral agents. Ulrich Desselberger, Gif-sur-Yvette/Cambridge. Infection of a naïve (non-immune) host with a virus elicits an immediate response which results in a cascade of changes in the host, including an interferon response (innate immunity). The outcome of this interaction is influenced by the genes of the virus as well as the genes of the host. Interestingly, different viruses do it in different ways. Not only is there a plethora of mechanisms used by the invading organisms, but the host has also evolved a great variety of redundant and robust countermeasures. This interplay of host and virus represents one of the most significant frontiers in biology today. A clearer understanding of the mechanisms involved will arm us with better strategies to deal with viruses, including emerging pathogens and potential bioterrorism agents. This book is sure to benefit students, scientists, and physicians working in the areas of virology, immunology, microbiology, and infectious diseases. Pharmaceutical industry professionals will also find interest in this illuminating look into virus/host interactions.
Immunologic diseases. --- Host-virus relationships. --- Virus diseases --- Immunological aspects. --- Relationships, Host-virus --- Virus-host relationships --- Host-parasite relationships --- Immune diseases --- Immune disorders --- Immune system --- Immunologic disorders --- Immunological diseases --- Diseases --- Microbiology. --- Immunology. --- Medical virology. --- Emerging infectious diseases. --- Virology. --- Infectious Diseases. --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Medical microbiology --- Virology --- Immunobiology --- Life sciences --- Serology --- Microbial biology --- Biology --- Microorganisms --- Infectious diseases. --- Microbiology
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Emergency Abdominal Surgery is a battlefield for the surgeon - providing character-building experiences, and opportunities for triumph and disaster. In the second edition of this 'simple' book emergency abdominal surgery is discussed in an informal and no nonsense fashion - as practiced in the 'trenches' of the ER and the OR. The preferred approach for a given situation is discussed in context; it has to fulfill certain prerequisites: save live, decrease morbidity, be cost effective and be performed correctly. Review of the 1st Edition: 'What makes this book very readable are the 'pregnant' citations, aphorisms and 'smart savings', which are often heard at the bedside and operation rooms but almost never reach the pages of a book'. (P. Klein, Chirurg, 2000). ' This is written with short punchy chapters making it very difficult to put down....'. (R A B Wood, Journal Royal College of Surgeons of Edinburgh, 2000) ' Since Mondor's times in the forties of the last century there was no other book in surgery to be written so easy and witty...' (Boris D. Savchuk, World Journal of Surgery, 2002).
Abdomen --- Surgical emergencies. --- Surgery. --- Critical care surgery --- Emergency surgery --- Medical emergencies --- Surgery --- Abdominal surgery --- Laparotomy --- Emergency medicine. --- Trauma. --- Emerging infectious diseases. --- Critical care medicine. --- General Surgery. --- Emergency Medicine. --- Traumatic Surgery. --- Infectious Diseases. --- Intensive / Critical Care Medicine. --- Intensive care --- Intensive medicine --- Medicine --- Emergency medicine --- Intensive care units --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Medicine, Emergency --- Critical care medicine --- Disaster medicine --- Surgery, Primitive --- Traumatology. --- Infectious diseases. --- Accident medicine --- Trauma medicine --- Wounds and injuries
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