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Regional cancer therapies remain important options in the management of malignant disease, in spite of the venue of more targeted agents for systemic therapies. New te- nologies and better guidance systems for radiofrequency ablation and intrastitial laser therapies, highly selective intravascular approaches with improved catheters and gu- ance systems, improved agents for embolizations, and new vasoactive drugs for isolated limb and liver perfusions are just a few of the new developments in a field that is alive and progressing. Regional Cancer Therapy, so well put together by the editors Peter M. Schlag and Ulrike S. Stein, presents an overview of today’s realities and tomorrow’s possibilities. Regional cancer therapy models provide ways to make new discoveries about tumor biology and new agents that may be used regionally as well as systemically. This book should therefore be of interest to all clinicians and scientists with an interest in tumor biology as well as clinical advances. Alexander M. M. Eggermont, MD, PhD Professor and Head of Surgical Oncology Erasmus University MC—Daniel den Hoed Cancer Center Rotterdam, the Netherlands v PREFACE The treatment of malignant tumors has been substantially improved in recent years due to developments in clinical medicine and technology as well as by advances in mole- lar biological research. Modern molecular and genetic techniques allow the charact- ization of molecules that are decisive for tumor development and progression.
Cancer --- Drug targeting. --- Infusion therapy. --- Antineoplastic agents --- Chemotherapy. --- Administration. --- Drugs --- Site-specific drug delivery --- Targeting of drugs --- Target organs (Anatomy) --- Infusions (Therapeutics) --- Parenteral therapy --- Anticancer agents --- Antineoplastic drugs --- Antineoplastics --- Antitumor agents --- Antitumor drugs --- Cytotoxic drugs --- Inhibitors, Neoplasm --- Neoplasm inhibitors --- Targeting --- Dosage forms --- Treatment --- Chemotherapy
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There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer and it offers radically new ideas about how therapy can be improved by attacking these principles. Following work that firmly establishes immune escape as an essential trait of cancer, recent studies have now defined specific mechanisms of tumoral immune suppression. It also demonstrates how attacking tumors with molecular targeted therapeutics or traditional chemotherapeutic drug
Cancer --- Antineoplastic Agents --- Tumors --- Immunotherapy --- therapeutic use --- Immunological aspects --- Antineoplastic agents --- Tumor immunology --- Anticancer agents --- Antineoplastic drugs --- Antineoplastics --- Antitumor agents --- Antitumor drugs --- Cytotoxic drugs --- Inhibitors, Neoplasm --- Neoplasm inhibitors --- Drugs --- Immunotherapy. --- Therapeutic use. --- Immunological aspects. --- Chemotherapy --- Treatment --- Cancer - Immunotherapy --- Antineoplastic Agents - therapeutic use --- Tumors - Immunological aspects
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Reviews the advances in cancer chemotherapy research. This book is of interest to scientists engaged in drug research in the pharmaceutical industry, biotechnology and startup companies, academia and government institutions. It reflects a range of medicinal chemistry approaches to small molecule drugs, including anti-hormonal therapy.
Antineoplastic agents --- Cancer --- Pharmaceutical chemistry --- Chemistry, Pharmaceutical --- Antineoplastic Agents --- Anticancéreux --- Chimie pharmaceutique --- Chemotherapy --- Chimiothérapie --- Antineoplastic agents. --- Neoplasms --- Diseases --- Therapeutic Uses --- Pharmacologic Actions --- Chemical Actions and Uses --- Chemicals and Drugs --- Pharmacy, Therapeutics, & Pharmacology --- Oncology --- Medicine --- Health & Biological Sciences --- Pharmaceutical chemistry. --- Anticancéreux --- Chimiothérapie --- EPUB-LIV-FT LIVCHIMI SPRINGER-B --- Chemistry, Medical and pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Anticancer agents --- Antineoplastic drugs --- Antineoplastics --- Antitumor agents --- Antitumor drugs --- Cytotoxic drugs --- Inhibitors, Neoplasm --- Neoplasm inhibitors --- Chemistry --- Chemistry. --- Molecular biology. --- Pharmacology. --- Organic chemistry. --- Medicinal chemistry. --- Medicinal Chemistry. --- Pharmacology/Toxicology. --- Organic Chemistry. --- Molecular Medicine. --- Chemistry, Pharmaceutical. --- Antineoplastic Agents. --- Biochemistry. --- Toxicology. --- Chemistry, Organic. --- Medicine. --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Organic chemistry --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Toxicology --- Composition --- Health Workforce --- Drug effects --- Medical pharmacology --- Pharmacy --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Physiological effect
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