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This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of gene repertoires encoded by completely sequenced genomes. The author discusses the underlying scientific principles of comparative genomics, argues that completion of many genome sequences started a new era in biology, and provides a personal view on several state-of-the-art issues, such as
Genomics. --- Gene mapping. --- Physiology, Comparative. --- Comparative physiology --- Chromosome mapping --- Genetic mapping --- Genome mapping --- Linkage mapping (Genetics) --- Mapping, Gene --- Genome research --- Genomes --- Research --- Medicine, Comparative --- Zoology --- Genetics --- Molecular genetics --- Technique
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This book describes a novel and unique approach to the treatment of human diseases based on the study of natural animal models. A natural animal model is defined as an animal group or species that possesses a set of biochemical/physiological characteristics which are natural and adaptive for that animal, but are quite abnormal for humans. For example, how is it that birds can tolerate blood glucose concentrations which in humans are associated with diabetes. The natural animal model is living proof that a biological answer to this question is available. By studying natural animal models, we ca
Diseases --- Physiology, Comparative. --- Laboratory animals. --- Animals, Experimental --- Animals, Laboratory --- Animals in research --- Experimental animals --- Lab animals --- Animal culture --- Laboratory organisms --- Working animals --- Animal experimentation --- Comparative physiology --- Medicine, Comparative --- Zoology --- Animal disease models --- Disease models, Animal --- Animal models in research --- Medicine, Experimental --- Pathology, Comparative --- Pathology, Experimental --- Animal models. --- Physiology, Comparative
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