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Foundations of comparative genomics
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ISBN: 128103696X 9786611036966 0080546099 0120887940 Year: 2007 Publisher: Amsterdam ; Boston : Academic Press,

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Abstract

This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of gene repertoires encoded by completely sequenced genomes. The author discusses the underlying scientific principles of comparative genomics, argues that completion of many genome sequences started a new era in biology, and provides a personal view on several state-of-the-art issues, such as

Comparative physiology, natural animal models, and clinical medicine
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ISBN: 1281867551 9786611867553 1860949495 9781860949494 9781281867551 6611867554 9781860947827 1860947824 Year: 2007 Publisher: London Imperial College Press

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This book describes a novel and unique approach to the treatment of human diseases based on the study of natural animal models. A natural animal model is defined as an animal group or species that possesses a set of biochemical/physiological characteristics which are natural and adaptive for that animal, but are quite abnormal for humans. For example, how is it that birds can tolerate blood glucose concentrations which in humans are associated with diabetes. The natural animal model is living proof that a biological answer to this question is available. By studying natural animal models, we ca

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