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In this updated third edition of the critically-acclaimed volume, expert physicians assemble user-friendly, clinically-oriented guides to aid in the day-to-day management of the allergic patient. With an emphasis on common allergic diseases and the pharmacological tools to control them, Allergic Diseases: Diagnosis and Treatment, Third Edition disseminates the practical knowledge that practitioners have accumulated through practice and teaching in the field of allergy and immunology. This entirely revised third edition updates topics from the second edition and now covers in detail the use of antihistamines and antileukotrienes. Another new chapter will help physicians treat children who experience recurrent respiratory tract infections. Other topics include diagnostic tests, insect stings, sinusitis and otitis media, ocular allergy, atopic dermatitis, and food allergy. Allergic Disease: Diagnosis and Treatment, Third Edition, is intended for the front-line physician who cares for allergic patients and will help any physician improve the care offered to those patients.

Allergy --- Hypersensitivity --- Allergic diseases --- Allergies --- Hypersensitivity, Immediate --- Immediate allergy --- Immediate hypersensitivity --- Immunologic diseases --- Immunoglobulin E --- diagnosis --- therapy

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L’esigenza di chiarire i concetti attuali dell’atopia, che per troppo tempo hanno oscillato tra una primitiva visione squisitamente clinica ed una successiva unicamente immunologica, era matura da tempo. L’avere compreso che il ruolo delle immunoglobuline E non è esaustivo ed avere accettato la salomonica divisione tra atopia intrinseca ed estrinseca, sono stati i primi due passi fondamentali. Le recenti scoperte del ruolo dell’immunità innata, e quindi dei peptidi antimicrobici, hanno aperto dei fondamentali spazi di comprensione nell’atopia e non solo. Quello che ora appare chiaro è che l’atopia non è la malattia di un organo ma piuttosto un difetto delle membrane che delimitano il nostro "self". Il fatto che queste membrane si chiamino pelle, intestino, congiuntiva, bronchi o quant’altro ha artificialmente frammentato la comprensione ed il trattamento di un fenomeno unitario. Questo libro vuole cercare di fare una sintesi delle diverse esperienze ma soprattutto essere uno stimolo a far sì che la medicina si focalizzi costruttivamente sullo stesso bersaglio. Se così sarà, non assisteremo più a"guerre di religione" tra scienziati e medici pratici o, peggio ancora, tra i differenti specialisti che si contendono il paziente. Se l’atopia, come noi crediamo, è un problema globale, esso può essere adeguatamente affrontato solo in un contesto pluridisciplinare e in clima collaborativo, non solo tra medico e medico ma anche tra medico e paziente.

Atopic dermatitis --- Treatment. --- Prevention. --- Atopic eczema --- Eczema, Atopic --- Allergy --- Skin --- Inflammation --- Dermatology. --- Allergy. --- Immunology. --- Allergology. --- Allergic diseases --- Allergies --- Hypersensitivity --- Hypersensitivity, Immediate --- Immediate allergy --- Immediate hypersensitivity --- Immunologic diseases --- Immunoglobulin E --- Medicine --- Immunobiology --- Life sciences --- Serology --- Diseases

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The goal of the International Immune-Mediated Diseases: From Theory to Therapy (IMD) Congress is to bring the best world immunologists and clinicians to Moscow to participate in plenary sessions, symposia and educational workshops designed to expose basic and clinical immunologist as well as practicing clinicians to the newest developments in the field. First IMD Congress consisted of 8 Plenary Sessions, 40 Symposia and 25 Workshops. The meeting attracted almost 2000 participants and speakers from 15 countries. After this great success of the First IMD Congress, the Organizing Committee decided to convene the meeting every other year and the Second International IMD Congress was planned for September 2007. Special attention will be given to innovative therapeutic modalities, allergy and asthma, immunodeficiency, tumor and transplant immunology, immunotherapy and vaccines, HIV and infectious diseases, autoimmune diseases, inflammation, immunomonitoring and immunodiagnostics. This volume includes contributions from the speakers of the Second IMD Congress (September 10-15, 2007; Moscow, Russia) who are eager to share some of the academic and clinical enthusiasm that defines the IMD meetings.

Autoimmune diseases --- Immunologic diseases --- Medicine. --- Immunology. --- Virology. --- Microbiology. --- Biomedicine. --- Medicine/Public Health, general. --- Microbial biology --- Biology --- Microorganisms --- Microbiology --- Immunobiology --- Life sciences --- Serology --- Clinical sciences --- Medical profession --- Human biology --- Medical sciences --- Pathology --- Physicians --- Immune diseases --- Immune disorders --- Immune system --- Immunologic disorders --- Immunological diseases --- Diseases --- Medical virology. --- Medical microbiology --- Virology --- Virus diseases --- Health Workforce

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The idea for this book was born during the symposium on biologics organized by ZAFES (Center for Drug Research, Development and Safety at the University of Frankfurt am Main) in September 2005. Highly distinguished researchers special- ing in the field of biologics had gathered together to exchange information on this relatively new subject. Realizing that this symposium was one of the few sources of condensed information on biologics, it became obvious that we had to create a means of informing an interested wider circle of scientists and especially general c- nicians. Therefore, the editors of this book suggested to the researchers at the symposium andalsotoprominent scientists andcliniciansinvolvedinthe developmentand application of biologics as their major field of interest the idea of assembling this compendium. We received an overwhelmingly positive response – thankfully also from the publisher – most being more than willing to support this innovative project with highly relevant chapters on the latest state of the art. As we were eager to fill the information gap with up-to-date knowledge, the project had to be finished within the shortest time possible. To all experienced with editing this was obviously a ch- lengeand we areverythankfultoall thecontributorsthatour timeline hadtobe extended by only a few months. This book represents a collection of the most recent knowledge on biologics written by people who have been active in the field for many years. Wolf-Henning Boehncke Heinfried H. Radeke Contents 1 Introduction: Definition and Classification of Biologics W. -H. Boehncke, H. H. Radeke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Biological products. --- Pharmaceutical technology. --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Technology --- Bioproducts --- Products, Biological --- Natural products --- Metabolites --- Dermatology. --- Immunology. --- Allergy. --- Gastroenterology. --- Rheumatology. --- Allergology. --- Internal medicine --- Connective tissues --- Joints --- Digestive organs --- Allergic diseases --- Allergies --- Hypersensitivity --- Hypersensitivity, Immediate --- Immediate allergy --- Immediate hypersensitivity --- Immunologic diseases --- Immunoglobulin E --- Immunobiology --- Life sciences --- Serology --- Medicine --- Skin --- Diseases --- Gastroenterology .

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This comprehensive volume assembles the insights and experience of over twenty experts and thought leaders in the field of autoimmune disease and immunotherapy. These discussions represent some of the newest concepts in autoimmune mechanisms and an array of new treatments that would have been considered science fiction only two decades ago. This book provides a wide-ranging review of two main arenas of current research: that of autoimmune mechanisms of disease and that of the latest developments in immunotherapy, with an emphasis upon multiple sclerosis. The conclusions reached by these authors will influence our thinking about autoimmune disease mechanisms and our methods of patient treatment in one of the fastest developing areas of modern medicine. Immune Regulation and Immunotherapy in Autoimmune Disease is an ideal book for researchers, clinicians, physicians, and graduate students in the fields of immunology, microbiology, infectious disease, virology, pharmacology, and medicine.

Autoimmune diseases --- Immune response --- Immunotherapy. --- Regulation. --- Immune modulation --- Immunity --- Immunomodulation --- Immunoregulation --- Regulation of immunity --- Regulation of the immune response --- Idiotypic networks --- Biological response modifiers --- Ir genes --- Autoimmunologic diseases --- Autoimmunity --- Immunologic diseases --- Regulation --- Immunology. --- Microbiology. --- Emerging infectious diseases. --- Medical virology. --- Toxicology. --- Infectious Diseases. --- Virology. --- Pharmacology/Toxicology. --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Medical microbiology --- Virology --- Virus diseases --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Microbial biology --- Biology --- Microorganisms --- Immunobiology --- Life sciences --- Serology --- Toxicology --- Infectious diseases. --- Pharmacology. --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Drugs --- Pharmacy --- Microbiology --- Physiological effect