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Indwelling neural implants : strategies for contending with the in vivo environment
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ISBN: 0849393620 1322617813 1420009303 042912354X Year: 2007 Publisher: Boca Raton : Taylor & Francis,

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Abstract

Despite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwelling Neural Implants: Strategies for Contending with the In Vivo Environment examines many of these challenges, paying particular attention to how the healing of tissues surrounding an implant can impact the intended use of a device. The contributions are

Handbook of Neurochemistry and Molecular Neurobiology : Amino Acids and Peptides in the Nervous System
Authors: --- ---
ISBN: 0387303731 0387303421 Year: 2007 Publisher: New York, NY : Springer US : Imprint: Springer,

Handbook of Neurochemistry and Molecular Neurobiology : Neural Protein Metabolism and Function
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ISBN: 0387303790 0387303464 Year: 2007 Publisher: New York, NY : Springer US : Imprint: Springer,


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Neuroendocrine Cells and Peptidergic Innervation in Human and Rat Prostate
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ISBN: 1280863625 9786610863624 3540698167 3540698159 Year: 2007 Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,

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Abstract

1 Introduction The prostate causes a significant number of medical problems in the adult male, and the lower urinary tract symptoms are accepted as an unavoidable consequence of male aging. Most of these symptoms are mainly due to clinical benign prostatic hyperplasia (BPH), which is the most frequent benign tumor in the male, independent of race or culture. On the other hand, cancer of the prostate shows an increasing incidence, being the second leading cause of death in men, after lung cancer. It has an etiology related to multiple factors: age, race, androgen dependence, chemical agents, diet, etc. Both pathologies are very costly in terms of medical resources, and they significantly diminish quality of life. More than 400,000 prostate resections per year are done in the US, and these result in an approximate cost of 5 billion dollars per year. Because of all these circumstances, a better knowledge of the mechanisms regulating normal, hyperplastic, and neoplastic prostate growth is important for treatment and prevention of BPH and prostate cancer. Since the last review about prostate neuroendocrine cells published in 1998 there have been new and exciting developments relating to these cells in both normal and pathologic prostate. The cross talk of signals between epithelial and neuroendocrine cells seems relevant to the development and physiopathology of the prostate; thus the relationship between these cell populations should be more deeply studied.

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