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Animals --- Plants --- Oxidation-reduction reaction --- Energy metabolism
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Vascular injury is initiated by oxidant injury to the vessel wall. This volume is organized around the role of oxidant damage in this disease process and provides a collection of the most recent studies, representing various disciplines, that can serve as the basis for further improvements in our understanding and control of cardiovascular and cerebral vascular disease. Jordan L. Holtzman, M.D., Ph.D. is Professor, Departments of Pharmacology and Medicine and Division of Environmental Health Sciences, University of Minnesota, Minneapolis, Minnesota.
Medicine. --- Cardiology. --- Medicine & Public Health. --- Heart --- Internal medicine --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Diseases --- Atherosclerosis. --- Oxidative stress. --- Oxidation-reduction reaction --- Stress (Physiology) --- Arteriosclerosis
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Oxidative Stress in Aging: From Model Systems to Human Diseases discusses the role of free radicals in aging in different animal models, as well as the relevance of free radicals on age-related diseases and pathological conditions in humans (following an introduction section of the basics and theory of free radicals). Human aging is a complex phenomenon - not everyone gets the same diseases and dies from the same cause. Accumulating reports implicate the connection between free radicals and various diseases and age-related pathological conditions. Although the causal relationships have not been established, it is necessary to discuss how free radicals are involved in each situation. In addition, the major interventions trials of antioxidant supplements in age-related disease, cancer and so forth are reviewed and discussed.
Oxidative stress --- Aging --- Pathophysiology. --- Physiological aspects. --- Oxidation-reduction reaction --- Stress (Physiology) --- Geriatrics. --- Internal medicine. --- Cytology. --- Geriatrics/Gerontology. --- Internal Medicine. --- Cell Biology. --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Medicine --- Gerontology --- Older people --- Medicine, Internal --- Diseases --- Health and hygiene --- Cell biology.
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The Nobel Prize was awarded in Physiology or Medicine in 1998 to Louis J. Ignarro, Robert F. Furchgott and Ferid Murad for demonstrating the signaling properties of nitric oxide. Nitric oxide (NO) is one of the few gaseous signaling molecules and is a key biological messenger that plays a role in many biological processes. NO research has led to new treatments for treating heart as well as lung diseases, shock and impotence. (Sildenafil, popularly known by the trade name Viagra, enhances signaling through NO pathways.) Scientists are currently testing whether NO can be used to stop the growt
Nitric oxide -- Pathophysiology. --- Nitric oxide -- Physiological effect. --- Nitric oxide. --- Oxidative Stress --- Nitric Oxide --- Oxidation-Reduction --- Signal Transduction --- Nitrogen Oxides --- Energy Metabolism --- Physicochemical Processes --- Metabolism --- Stress, Physiological --- Reactive Nitrogen Species --- Free Radicals --- Biochemical Processes --- Cell Physiological Processes --- Nitrogen Compounds --- Chemical Processes --- Inorganic Chemicals --- Cell Physiological Phenomena --- Biochemical Phenomena --- Metabolic Phenomena --- Oxides --- Physicochemical Phenomena --- Physiological Processes --- Oxygen Compounds --- Phenomena and Processes --- Chemical Phenomena --- Physiological Phenomena --- Chemicals and Drugs --- Animal Biochemistry --- Human Anatomy & Physiology --- Health & Biological Sciences --- Oxidative stress. --- Physiology, Pathological. --- Nitric oxide --- Physiological effect. --- Endothelial relaxing factor --- Endothelium-derived relaxing factors --- Nitrogen oxide --- Clinical physiology --- Pathological physiology --- Pathophysiology --- Physiopathology --- Neurotransmitters --- Nitrogen compounds --- Pathology --- Physiology --- Oxidation-reduction reaction --- Stress (Physiology)
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Oxidative Stress --- Cell aging --- Oxidative stress --- Cells --- Stress oxydatif --- Cellules --- Periodicals --- Aging --- Périodiques --- Vieillissement --- Oxidative Stress. --- Cell Aging. --- Oxidative stress. --- Aging. --- Life Sciences --- Biology --- oxidative stress --- cell aging --- Cell Aging --- Oxidation-reduction reaction --- Stress (Physiology) --- Organisms --- Cytology --- Cell Ageing --- Cellular Ageing --- Cellular Aging --- Senescence-Associated Secretory Phenotype --- Aging, Cell --- Cell Senescence --- Replicative Senescence --- Senescence, Cellular --- Senescence, Replicative --- Ageing, Cell --- Ageing, Cellular --- Aging, Cellular --- Phenotype, Senescence-Associated Secretory --- Secretory Phenotype, Senescence-Associated --- Senescence Associated Secretory Phenotype --- Senescence, Cell --- Stress, Oxidative --- Oxidative Stresses --- Stresses, Oxidative --- Nitrosative Stress --- Antioxidants --- Reactive Oxygen Species --- Cellular Senescence --- Cellular Senescence. --- Periodicals. --- Anti-oxidative Stress --- Antioxidative Stress --- DNA Oxidative Damage --- Nitro-Oxidative Stress --- Oxidative Cleavage --- Oxidative DNA Damage --- Oxidative Damage --- Oxidative Injury --- Oxidative Nitrative Stress --- Oxidative Stress Injury --- Oxidative and Nitrosative Stress --- Anti oxidative Stress --- Anti-oxidative Stresses --- Antioxidative Stresses --- Cleavage, Oxidative --- DNA Damage, Oxidative --- DNA Oxidative Damages --- Damage, DNA Oxidative --- Damage, Oxidative --- Damage, Oxidative DNA --- Injury, Oxidative --- Injury, Oxidative Stress --- Nitrative Stress, Oxidative --- Nitro Oxidative Stress --- Nitro-Oxidative Stresses --- Oxidative Cleavages --- Oxidative DNA Damages --- Oxidative Damage, DNA --- Oxidative Damages --- Oxidative Injuries --- Oxidative Nitrative Stresses --- Oxidative Stress Injuries --- Stress Injury, Oxidative --- Stress, Anti-oxidative --- Stress, Antioxidative --- Stress, Nitro-Oxidative --- Stress, Oxidative Nitrative --- Stresses, Nitro-Oxidative --- Histology. Cytology
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