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This book constitutes the refereed proceedings of the 13th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2009, held in Tucson, Arisona, USA in May 2009. The 37 revised full papers presented were carefully reviewed and selected from 166 submissions. As the top conference in computational molecular biology, RECOMB addresses all current issues in algorithmic, theoretical, and experimental bioinformatics such as molecular sequence analysis, recognition of genes and regulatory elements, molecular evolution, protein structure, structural genomics, gene expression, gene networks, drug design, combinatorial libraries, computational proteomics, as well as structural and functional genomics.

Computational Biology --- Genomics --- Sequence Analysis --- Gene Expression --- Genetics --- Biology --- Genetic Processes --- Genetic Techniques --- Genetic Phenomena --- Biological Science Disciplines --- Investigative Techniques --- Natural Science Disciplines --- Phenomena and Processes --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Disciplines and Occupations --- Biology - General --- Health & Biological Sciences --- Bioinformatics. --- Molecular biology --- Mathematical models. --- Molecular biochemistry --- Molecular biophysics --- Bio-informatics --- Biological informatics --- Life sciences. --- Computer programming. --- Algorithms. --- Database management. --- Artificial intelligence. --- Life Sciences. --- Life Sciences, general. --- Programming Techniques. --- Artificial Intelligence (incl. Robotics). --- Computational Biology/Bioinformatics. --- Algorithm Analysis and Problem Complexity. --- Database Management. --- Information science --- Computational biology --- Systems biology --- AI (Artificial intelligence) --- Artificial thinking --- Electronic brains --- Intellectronics --- Intelligence, Artificial --- Intelligent machines --- Machine intelligence --- Thinking, Artificial --- Bionics --- Cognitive science --- Digital computer simulation --- Electronic data processing --- Logic machines --- Machine theory --- Self-organizing systems --- Simulation methods --- Fifth generation computers --- Neural computers --- Data base management --- Data services (Database management) --- Database management services --- DBMS (Computer science) --- Generalized data management systems --- Services, Database management --- Systems, Database management --- Systems, Generalized database management --- Algorism --- Algebra --- Arithmetic --- Computers --- Electronic computer programming --- Electronic digital computers --- Programming (Electronic computers) --- Coding theory --- Biosciences --- Sciences, Life --- Science --- Data processing --- Foundations --- Programming --- Biochemistry --- Biophysics --- Biomolecules --- Computer science. --- Computer software. --- Artificial Intelligence. --- Software, Computer --- Computer systems --- Informatics