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2010 (4)

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Digital
Vitiligo
Authors: ---
ISBN: 9783540693611 9783540865391 9783540693604 9783642422744 Year: 2010 Publisher: Berlin, Heidelberg Springer

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Abstract

Vitiligo has been, until recently, a rather neglected area in dermatology and medicine. Patients complain about this situation, which has offered avenues to quacks, and has led to the near orphan status of the disease. The apparently, simple and poorly symptomatic presentation of the disease has been a strong disadvantage to its study, as compared to other common chronic skin disorders such as psoriasis and atopic dermatitis. Vitiligo is still considered by doctors as a non disease, a simple aesthetic problem. A good skin-based angle of attack is also lacking because generalized vi- ligo is clearly epitomizing the view of skin diseases as simple targets of a systemic unknown dysregulation (diathesis), re? ecting the Hippocratic doctrine. This view has mostly restricted vitiligo to the manifestation of an auto-immune diathesis in the past 30 years. Thus, skin events, which are easily detected using skin biospies in most other situations, have not been precisely recorded, with the argument that a clinical diagnosis was suf? cient for the management (or most commonly absence of mana- ment) of the patient. This book is an international effort to summarize the information gathered about this disorder at the clinical, pathophysiological and therapeutic levels. Its primary aim is to bridge current knowledge at the clinical and investigative level, to point to the many unsolved issues, and to delineate future priorities for research.


Digital
Aging Hair
Authors: ---
ISBN: 9783642026362 9783642026379 9783642026355 9783642422881 Year: 2010 Publisher: Berlin, Heidelberg Springer

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“Aged? But he does not appear aged, just look, his hair has remained young!” Marcel Proust, In Search of Lost Time (1913–27) The appearance of hair plays an important role in peoples’ overall physical appe- ance and self-perception. With today’s increasing life-expectation, the desire to look youthful plays a bigger role than ever. The hair care industry has become aware of this, and capable to deliver active products that are directed toward meeting this c- sumer demand. The discovery of pharmacological targets and the development of safe and effective drugs such as minoxidil and fnasteride also indicate strategies of the drug industry for maintenance of healthy and beautiful hair in the young and old. The study of hair aging focuses on two main streams of interest: On the one hand, the esthetic problem of aging hair and its management, in other words everything that happens outside the skin; on the other hand, the biological problem of aging hair, in terms of microscopic, biochemical, and molecular changes, in other words the “secret life” of the hair follicle in the depth of the skin. Hair aging comprises hair shaft aging, and aging of the hair follicle. The former involves weathering and photoaging of the hair shaft, while the latter manifests as decrease of melanocyte function (graying) and decrease in hair production (alopecia).


Book
The Jews of North Africa
Authors: ---
ISBN: 0761850449 1299636489 9781299636484 9780761850441 9780761850434 0761850430 Year: 2010 Publisher: Lanham, Md. University Press of America

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This book explores the history of North African Jews, detailing the Islamic conquest of 698 and life under French colonization from 1830 to 1962, and explaining the effects of these rules on the Jewish population.


Book
Beroepenwetgeving gezondheidszorg 2010/2011
Authors: --- --- --- --- --- et al.
ISBN: 9789031376438 9789031376445 Year: 2010 Publisher: Houten Bohn Stafleu van Loghum

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