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Sociology --- Overweight --- Overnutrition --- Socioeconomic Factors --- Age Groups --- Body Weight --- Nutrition Disorders --- Social Sciences --- Persons --- Population Characteristics --- Body Size --- Signs and Symptoms --- Named Groups --- Health Care --- Anthropology, Education, Sociology and Social Phenomena --- Nutritional and Metabolic Diseases --- Diseases --- Body Weights and Measures --- Pathological Conditions, Signs and Symptoms --- Body Constitution --- Physiological Phenomena --- Physical Examination --- Phenomena and Processes --- Diagnostic Techniques and Procedures --- Diagnosis --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Obesity --- Adolescent --- Child --- Social Conditions
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Overnutrition --- History --- Overweight --- Body Weight --- Humanities --- Nutrition Disorders --- Body Size --- Nutritional and Metabolic Diseases --- Signs and Symptoms --- Body Weights and Measures --- Diseases --- Pathological Conditions, Signs and Symptoms --- Body Constitution --- Physical Examination --- Physiological Phenomena --- Phenomena and Processes --- Diagnostic Techniques and Procedures --- Diagnosis --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Obesity --- History, Medieval --- History, Early Modern 1451-1600 --- History, Modern 1601 --- -Medicine --- Health & Biological Sciences --- Metabolic & Nutritional Diseases
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The prevalence of obesity has dramatically increased in western and westernized societies, making the disease the second leading cause of unnecessary deaths in the US. Obesity results from imbalanced metabolic regulation leading to excessive lipid storage. As important novel entities in metabolic regulation, taste receptors and their cells are critical elements that adapt the gustatory system to metabolic signals and vice versa. The role of taste receptor genes in gastrointestinal tissues, as well as their dynamic regulation in gustatory and non-gustatory tissues in response to metabolic cues, has become the focus of an entirely new and rapidly developing research field with impacts on fuel sensing, metabolic control, and ingestive behavior. This book reflects the recent scientific progress in the field of fuel sensing in the mouth, GI tract, and brain and examines the olfactory bulb as a potential metabolic sensor and the brain-gut endocrine axis. It also touches on relevant novel molecular and cellular mechanisms regulating lipid storage and metabolism and covers the identification and functional characterization of obesity genes. Lastly, it illustrates the use of insect models to study relevant problems of energy homeostasis.
Bioenergetics. --- Chemoreceptors. --- Energy metabolism -- Regulation. --- Lipids -- Metabolism. --- Non-insulin-dependent diabetes -- Animal models. --- Obesity -- Animal models. --- Metabolism --- Chemoreceptors --- Bioenergetics --- Lipids --- Obesity --- Non-insulin-dependent diabetes --- Metabolic Phenomena --- Neurons, Afferent --- Peripheral Nervous System --- Overweight --- Overnutrition --- Nutrition Disorders --- Neurons --- Phenomena and Processes --- Body Weight --- Nervous System --- Energy Metabolism --- Sensory Receptor Cells --- Cells --- Body Size --- Signs and Symptoms --- Nutritional and Metabolic Diseases --- Anatomy --- Pathological Conditions, Signs and Symptoms --- Diseases --- Body Weights and Measures --- Body Constitution --- Physiological Phenomena --- Physical Examination --- Diagnostic Techniques and Procedures --- Diagnosis --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Human Anatomy & Physiology --- Biology --- Health & Biological Sciences --- Cytology --- Physiology --- Regulation --- Animal models --- Obesity. --- Research. --- Disorders. --- Adiposity --- Corpulence --- Fatness --- Disorders of metabolism --- Metabolic diseases --- Metabolic disorders --- Metabolism, Disorders of --- Anabolism --- Catabolism --- Metabolism, Primary --- Primary metabolism --- Life sciences. --- Cell biology. --- Life Sciences. --- Cell Biology. --- Body weight --- Nutrition disorders --- Biochemistry --- Disorders --- Cytology. --- Cell biology --- Cellular biology --- Cytologists
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Childhood obesity and its co-morbidities -- including type 2 diabetes, hypertension, dyslipidemia, sleep apnea, and fatty liver disease -- have seen striking increases in recent years. Despite a wealth of investigation, there is considerable controversy regarding the etiology of childhood obesity and the optimal approaches for prevention and treatment. Pediatric Obesity: Etiology, Pathogenesis, and Treatment addresses the controversy with a range of features that make it a unique resource for those who care for obese children and their families. Written from a perspective that is international in scope, the distinguished authors re-assess the roles of genetic and environmental factors in the pathogenesis of childhood obesity and critically review new studies of the effects of lifestyle, pharmacologic, and surgical interventions. The evidence-based approach of Pediatric Obesity: Etiology, Pathogenesis, and Treatment provides a comprehensive and invaluable guide for all healthcare providers concerned with the evaluation and care of children with nutritional and metabolic disease and with the societal implications of the obesity epidemic.
Obesity in adolescence. --- Obesity in children -- Prevention. --- Obesity in children -- Treatment. --- Obesity in children. --- Overweight children -- Nutrition. --- Obesity in children --- Overweight --- Overnutrition --- Age Groups --- Body Weight --- Persons --- Nutrition Disorders --- Obesity --- Adolescent --- Child --- Nutritional and Metabolic Diseases --- Signs and Symptoms --- Named Groups --- Body Size --- Diseases --- Body Weights and Measures --- Pathological Conditions, Signs and Symptoms --- Body Constitution --- Physical Examination --- Physiological Phenomena --- Diagnostic Techniques and Procedures --- Phenomena and Processes --- Diagnosis --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Medicine --- Health & Biological Sciences --- Pediatrics --- Clinical Endocrinology --- Genetic aspects --- Social aspects --- Treatment --- Genetic aspects. --- Social aspects. --- Treatment. --- Childhood obesity --- Corpulence in children --- Medicine. --- General practice (Medicine). --- Internal medicine. --- Pediatrics. --- Medicine & Public Health. --- General Practice / Family Medicine. --- Internal Medicine. --- Metabolic disorders in children --- Nutrition disorders in children --- Family medicine. --- Medicine, Internal --- Family practice (Medicine) --- General practice (Medicine) --- Physicians (General practice) --- Paediatrics --- Pediatric medicine --- Children --- Health and hygiene
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Obesity is considered as top at risk condition in the world and it is mandatory to identify the physiopathological causes involved in adipose tissue enlargement and related metabolic and cardiovascular health disorders. Environmental, behavioural, genetic, epigenetic and multiple biological factors interact to cause obesity. In this context adipose tissue depots have been under focus in the last decades and pivotal concepts have emerged from the studies of their complex biology. While the white adipose tissue (WAT) is the main energy repository in the body (mobilizing fatty acids according to body needs) thanks to white adipocyte properties, WAT is also a multicellular organ communicating with other body organs (brain, muscles, liver, pancreas, heart, vessels, etc…) via complex networks of endocrine signals. The discovery of leptin in 1994 led to recognize WAT as a master organ at the crossroad of a myriad of physiological interactions to control food intake, energy balance, glucose and lipid metabolism, immunity and reproduction. The phenotype, amount and biology of each WAT component are profoundly altered in human obesity. Adipose plasticity also accounts for the extraordinary capacity of adipose precursors to differentiate into functional cardiomyocytes, osteoblasts, haematopoietic and neural cells, a convenient property for regenerative medicine. Finally, while initially thought to exert a negligible role in humans, the discovery of brown adipose tissue in adults stimulates a novel interest for this tissue with high capacity to oxidize fatty acids.
Adipose tissues. --- Adipose tissues --- Connective Tissue --- Overweight --- Biological Science Disciplines --- Overnutrition --- Body Weight --- Tissues --- Natural Science Disciplines --- Nutrition Disorders --- Obesity --- Physiology --- Adipose Tissue --- Nutritional and Metabolic Diseases --- Body Size --- Signs and Symptoms --- Anatomy --- Disciplines and Occupations --- Body Weights and Measures --- Pathological Conditions, Signs and Symptoms --- Diseases --- Body Constitution --- Physical Examination --- Physiological Phenomena --- Diagnostic Techniques and Procedures --- Phenomena and Processes --- Diagnosis --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Human Anatomy & Physiology --- Health & Biological Sciences --- Connective tissues --- Areolar tissue --- Adipose tissue --- Body fat tissues --- Fat tissue --- Fatty tissue --- Medicine. --- Biomedicine. --- Biomedicine general. --- Collagen --- Elastic tissue --- Musculoskeletal system --- Fat --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Health Workforce --- Biomedicine, general. --- Paris <2009>
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Energy Balance and Cancer, Epidemiology and Overview is the first in a series of monographs to address the multiple facets of the world wide pandemic of overweight and obesity and its relation to cancer. This volume, authored by leading experts in their perspective fields, provides a broad and comprehensive overview of the problem from the epidemiologic viewpoint with focus on both general and special populations as well as a description of potential molecular mechanisms and reviews of the latest studies of factors impacting the association of energy balance and cancer including the effects of genetics, caloric restriction, exercise, behavior and the built environment. The collected chapters and the authors contributing to this initial volume represent a transdisciplinary approach to analyze and develop novel approaches to understand and solve what, up to now, is a globally refractory problem. The book is written to be understandable and informative to individuals from all concerned disciplines. It should serve to orient students, investigators, nutritionists, public health officials, community planners, clinicians and policy makers to the extent of the problem, its multiple dimensions and potential approaches for research and corrective interventions.
Cancer -- Epidemiology. --- Cancer -- Nutritional aspects.. --- Energy Metabolism -- United States. --- Neoplasms -- epidemiology -- United States. --- Neoplasms -- etiology -- United States. --- Nutritional Physiological Phenomena -- United States. --- Obesity -- complications -- United States. --- Cancer --- Overweight --- Diseases --- Metabolism --- Overnutrition --- Physiological Phenomena --- Obesity --- Nutritional Physiological Phenomena --- Energy Metabolism --- Neoplasms --- Nutrition Disorders --- Body Weight --- Metabolic Phenomena --- Phenomena and Processes --- Body Size --- Signs and Symptoms --- Nutritional and Metabolic Diseases --- Pathological Conditions, Signs and Symptoms --- Body Weights and Measures --- Body Constitution --- Physical Examination --- Diagnostic Techniques and Procedures --- Diagnosis --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Medicine --- Oncology --- Health & Biological Sciences --- Nutritional aspects --- Epidemiology --- Nutritional aspects. --- Epidemiology. --- Medicine. --- Cancer research. --- Pharmacology. --- Biomedicine. --- Cancer Research. --- Pharmacology/Toxicology. --- Oncology. --- Toxicology. --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Tumors --- Toxicology --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Drugs --- Pharmacy --- Cancer research --- Physiological effect
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Before 1980, rates were generally well below 10%. They have since doubled or tripled in many countries, and in almost half of the OECD, 50% or more of the population is overweight. A key risk factor for numerous chronic diseases, obesity is a major public health concern. This book contributes to evidence-based policy making by exploring multiple dimensions of the obesity problem. It examines the scale and characteristics of the epidemic, the respective roles and influence of market forces and governments, and the impact of interventions. It outlines an economic approach to the prevention of chronic diseases that provides novel insights relative to a more traditional public health approach. The analysis was undertaken by the OECD, partly in collaboration with the World Health Organization. The main chapters are complemented by special contributions from health and obesity experts, including Marc Suhrcke, Tim Lobstein, Donald Kenkel and Francesco Branca. “a valuable set of results and suggestions about the best preventive interventions to reduce the burden of obesity.” – Julio Frenk, Dean, Harvard School of Public Health “The positive message of this book is that the obesity epidemic can be successfully addressed.” – Ala Alwan, Assistant Director-General, World Health Organization “innovative and well-researched” – Martin McKee, Professor, London School of Hygiene & Tropical Medicine "A timely, valuable volume on a critical issue. Highly recommended."-Choice, July 2011
Obesity -- Economic aspects. --- Obesity -- Prevention. --- Obesity --- Overnutrition --- Overweight --- Body Weight --- Nutrition Disorders --- Body Size --- Nutritional and Metabolic Diseases --- Signs and Symptoms --- Pathological Conditions, Signs and Symptoms --- Body Weights and Measures --- Diseases --- Body Constitution --- Physical Examination --- Physiological Phenomena --- Diagnostic Techniques and Procedures --- Phenomena and Processes --- Diagnosis --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Diagnostic Technics and Procedures --- Technics and Procedures, Diagnostic --- Techniques and Procedures, Diagnostic --- Physiological Concepts --- Physiological Phenomenon --- Physiological Process --- Physiological Processes --- Concept, Physiological --- Concepts, Physiological --- Phenomena, Physiological --- Phenomenas, Physiological --- Phenomenon, Physiological --- Physiological Concept --- Process, Physiological --- Processes, Physiological --- Antemortem Diagnosis --- Diagnoses and Examinations --- Examinations and Diagnoses --- Postmortem Diagnosis --- Antemortem Diagnoses --- Diagnoses --- Diagnoses, Antemortem --- Diagnoses, Postmortem --- Diagnosis, Antemortem --- Diagnosis, Postmortem --- Postmortem Diagnoses --- Disease --- Examination, Physical --- Physical Examinations and Diagnoses --- Examinations, Physical --- Physical Examinations --- Body Constitutions --- Constitution, Body --- Constitutions, Body --- Body Measures --- Body Measure --- Measure, Body --- Measures, Body --- Symptoms and General Pathology --- Symptoms and Signs --- Body Sizes --- Size, Body --- Sizes, Body --- Nutritional Disorders --- Nutrition Disorder --- Nutritional Disorder --- Body Weights --- Weight, Body --- Weights, Body --- Hypernutrition --- methods --- diagnosis --- Sensitivity and Specificity --- Surgical Clearance --- Independent Medical Evaluation --- Anthropometry --- Nutritional Physiological Phenomena --- Hyperphagia --- Obesity Management --- Weight Gain --- Bariatrics --- Physical Exam --- Exam, Physical --- Exams, Physical --- Physical Exams --- Diagnostic Testing --- Testing, Diagnostic --- Diagnose
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