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2011 (27)

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Book
Biosemiotics : Nature, Culture, Science, Semiosis
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ISBN: 1607852578 Year: 2011 Publisher: [Place of publication not identified] : Open Humanities Press,

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Models and analysis of vocal emissions for biomedical applications : 7th International Workshop - August 25-27, 2011 Firenze, Italy
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Year: 2011 Publisher: Firenze : Firenze University Press,

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The MAVEBA Workshop proceedings, held on a biannual basis, collect the scientific papers presented both as oral and poster contributions, during the conference. The main subjects are: development of theoretical and mechanical models as an aid to the study of main phonatory dysfunctions, as well as the biomedical engineering methods for the analysis of voice signals and images, as a support to clinical diagnosis and classification of vocal pathologies.


Book
Models and analysis of vocal emissions for biomedical applications : 7th International Workshop - August 25-27, 2011 Firenze, Italy
Author:
Year: 2011 Publisher: Firenze : Firenze University Press,

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Abstract

The MAVEBA Workshop proceedings, held on a biannual basis, collect the scientific papers presented both as oral and poster contributions, during the conference. The main subjects are: development of theoretical and mechanical models as an aid to the study of main phonatory dysfunctions, as well as the biomedical engineering methods for the analysis of voice signals and images, as a support to clinical diagnosis and classification of vocal pathologies.


Book
Models and analysis of vocal emissions for biomedical applications : 7th International Workshop - August 25-27, 2011 Firenze, Italy
Author:
Year: 2011 Publisher: Firenze : Firenze University Press,

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Abstract

The MAVEBA Workshop proceedings, held on a biannual basis, collect the scientific papers presented both as oral and poster contributions, during the conference. The main subjects are: development of theoretical and mechanical models as an aid to the study of main phonatory dysfunctions, as well as the biomedical engineering methods for the analysis of voice signals and images, as a support to clinical diagnosis and classification of vocal pathologies.


Book
Dynamic Models in Biology
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ISBN: 1400840961 Year: 2011 Publisher: Princeton, NJ : Princeton University Press,

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From controlling disease outbreaks to predicting heart attacks, dynamic models are increasingly crucial for understanding biological processes. Many universities are starting undergraduate programs in computational biology to introduce students to this rapidly growing field. In Dynamic Models in Biology, the first text on dynamic models specifically written for undergraduate students in the biological sciences, ecologist Stephen Ellner and mathematician John Guckenheimer teach students how to understand, build, and use dynamic models in biology. Developed from a course taught by Ellner and Guckenheimer at Cornell University, the book is organized around biological applications, with mathematics and computing developed through case studies at the molecular, cellular, and population levels. The authors cover both simple analytic models--the sort usually found in mathematical biology texts--and the complex computational models now used by both biologists and mathematicians. Linked to a Web site with computer-lab materials and exercises, Dynamic Models in Biology is a major new introduction to dynamic models for students in the biological sciences, mathematics, and engineering.


Book
Chimpanzees in biomedical and behavioral research : assessing the necessity
Authors: ---
ISBN: 0309220394 9786613527189 0309220408 128012332X 9780309220408 9780309220392 0309220424 Year: 2011 Publisher: Washington, D.C. : National Academies Press,

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"For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future"--Publisher description.


Book
Network Biology : Methods and Applications
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ISBN: 1617792764 1617792756 Year: 2011 Publisher: Totowa, NJ : Humana Press : Imprint: Humana,

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While extremely large datasets describing gene sequences, mRNA transcripts, protein abundance, and metabolite concentrations are increasingly commonplace, these represent only starting ‘parts lists’ that are usually insufficient to unlock mechanistic insights on their own right.  Fortunately, as Network Biology: Methods and Applications examines, concepts emerging from the study of biological entities such as networks (e.g. functional interactions linking genes, proteins, metabolites, etc.) suggest that order rather than chaos prevails, with such principles as modular and hierarchical organization, reactive information-driven causal-response behaviours, systems robustness, co-evolution, and self-organization guiding the way.  This volume presents detailed, practical descriptions of the experimental and computational approaches currently prevalent in network biology as written by practiced experts in the field.  Written in the highly successful Methods in Molecular Biology™ series format, relevant chapters contain introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls.   Comprehensive and accessible, Network Biology: Methods and Applications provides an ensemble of procedures that will be of great value to a broad assortment of readers, ranging from graduate students to seasoned professionals looking to polish their skill sets.


Book
Weighted Network Analysis : Applications in Genomics and Systems Biology
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ISBN: 1493900226 1441988181 144198819X Year: 2011 Publisher: New York, NY : Springer New York : Imprint: Springer,

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This book presents state-of-the-art methods, software and applications surrounding weighted networks. Most methods and results also apply to unweighted networks. Although aspects of weighted network analysis relate to standard data mining methods, the intuitive network language and analysis framework transcend any particular analysis method. Weighted networks give rise to data reduction methods, clustering procedures, visualization methods, data exploratory methods, and intuitive approaches for integrating disparate data sets. Weighted networks have been used to analyze a variety of high dimensional genomic data sets including gene expression-, epigenetic-, methylation-, proteomics-, and fMRI- data. Chapters explore the fascinating topological structure of weighted networks and provide geometric interpretations of network methods. Powerful systems-level analysis methods result from combining network- with data mining methods. The book not only describes the WGCNA R package but also other software packages. Weighted gene co-expression network applications, real data sets, and exercises guide the reader on how to use these methods in practice, e.g. in systems-biologic or systems-genetic applications. The material is self-contained and only requires a minimum knowledge of statistics. The book is intended for students, faculty, and data analysts in many fields including bioinformatics, computational biology, statistics, computer science, biology, genetics, applied mathematics, physics, and social science. .


Book
Modeling in Systems Biology : The Petri Net Approach
Authors: --- ---
ISBN: 1849964734 9786612973222 1282973223 1849964742 Year: 2011 Publisher: London : Springer London : Imprint: Springer,

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The emerging, multi-disciplinary field of systems biology is devoted to the study of the relationships between various parts of a biological system, and computer modeling plays a vital role in the drive to understand the processes of life from an holistic viewpoint. Advancements in experimental technologies in biology and medicine have generated an enormous amount of biological data on the dependencies and interactions of many different molecular cell processes, fueling the development of numerous computational methods for exploring this data. The mathematical formalism of Petri net theory is able to encompass many of these techniques. This essential text/reference presents a comprehensive overview of cutting-edge research in applications of Petri nets in systems biology, with contributions from an international selection of experts. Those unfamiliar with the field are also provided with a general introduction to systems biology, the foundations of biochemistry, and the basics of Petri net theory. Further chapters address Petri net modeling techniques for building and analyzing biological models, as well as network prediction approaches, before reviewing the applications to networks of different biological classification. Topics and features: Investigates the modular, qualitative modeling of regulatory networks using Petri nets, and examines an Hybrid Functional Petri net simulation case study Contains a glossary of the concepts and notation used in the book, in addition to exercises at the end of each chapter Covers the topological analysis of metabolic and regulatory networks, the analysis of models of signaling networks, and the prediction of network structure Provides a biological case study on the conversion of logical networks into Petri nets Discusses discrete modeling, stochastic modeling, fuzzy modeling, dynamic pathway modeling, genetic regulatory network modeling, and quantitative analysis techniques Includes a Foreword by Professor Jens Reich, Professor of Bioinformatics at Humboldt University and Max Delbrück Center for Molecular Medicine in Berlin This unique guide to the modeling of biochemical systems using Petri net concepts will be of real utility to researchers and students of computational biology, systems biology, bioinformatics, computer science, and biochemistry. Dr. Ina Koch is a Professor and holds the Chair of Bioinformatics at the Johann Wolfgang Goethe-University Frankfurt am Main, Germany. Dr. Wolfgang Reisig is a Professor and holds the Chair in the Theory of Programming at the Humboldt University of Berlin, Germany. Dr. Falk Schreiber is a Professor and holds the Chair of Bioinformatics at the Martin Luther University Halle-Wittenberg, Germany, and the Coordinator of Bioinformatics at the Leibniz Institute of Plant Genetics and Crop Plant Research Gatersleben, Germany.


Book
Advanced methods of biomedical signal processing
Authors: ---
ISBN: 9780470422144 0470422149 9781118007747 1118007743 1118007735 1283273675 9786613273673 1118007727 Year: 2011 Publisher: Piscataway, New Jersey : [Piscataqay, New Jersey] : IEEE Press, IEEE Xplore,

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A complete introduction to the application of advanced signal processing methods to biomedical engineering problemsThis edited volume, which grew out of the GNB (Gruppo Nazionale di Bioingegneria, Italy) Summer School on Biomedical Signal Processing, explains some of the most advanced methodological signal processing techniques and applies them to biomedical engineering problems. Prominent experts in the areas of biomedical signal processing, biomedical data treatment, medicine, signal processing, system biology, and applied physiology introduce novel techniques and algorithms as well as their clinical or physiological applications.Divided into seven sections, Advanced Methods of Biomedical Signal Processing covers:. The peculiarities of biomedical signal processing with respect to more traditional applications of digital signal processing and their classification. An experimental physiologist's and cardiologist's view of the cardiovascular, central and autonomic nervous systems. An important link between biomedical signal processing and physiological modeling. Time-frequency, time-scale, and wavelet analysis. Advanced methods employed in complexity measurements. Computational genomics and proteomics. Key methods for signal classification, such as neural networks, neuro-fuzzy and genetic algorithmsThe book provides a compelling overview of techniques, such as multisource and multi-scale integration of information for physiology and clinical decision; the integration of signal processing methods with a modeling approach; complexity measurement from biomedical signals; higher order analysis in biomedical signals; and classification and parameter enhancement. Various contributions reveal that biomedical signal processing must be viewed in a wider context, with key links to the modeling phase of the signal-generating mechanisms, in order to better comprehend the behavior of the biological system under investigation.Graduate and PhD students in engineering/biomedical engineering courses, physics and applied mathematics, as well as research professionals in medical and biological sciences will highly benefit from this authoritative resource.

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