Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The complexity of problem understanding biochemical and molecular basis of healthy life, and eagerness to find simple solution necessitate evolution of technology like mutagenesis. The chapters of this book contain experiences of scientists working in the area of mutagenesis. It describes suitable experimental models (microorganism, plants or animals) for testing spontaneous and induced mutations which are useful for basic and translational research. It includes methods towards gene targeting, developing disease and pest resistant plants, creating temperature sensitive molecular machines, understanding mitochondrial mutagenesis, detecting anti-mutagens, improving genetic insight into impaired immunity and disease. It also describes mutagenesis induced by DNA damage. It has also provided advantage of in vitro transcription and translation to yield proteins with point mutations, deletions or insertions for studying stability, DNA-protein or protein-protein interaction. Trust, it will serve readers as valuable integrated resources emphasizing methods of mutagenesis, and understanding mechanism of variable penetrance or expressivity of mutations.

Mutagenesis --- Methodology. --- Mutation (Biology) --- Radiogenetics --- Teratogenesis --- Genetic engineering

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Analysis of Genetic Variation in Animals includes chapters revealing the magnitude of genetic variation existing in animal populations. The genetic diversity between and within populations displayed by molecular markers receive extensive interest due to the usefulness of this information in breeding and conservation programs. In this concept molecular markers give valuable information. The increasing availability of PCR-based molecular markers allows the detailed analyses and evaluation of genetic diversity in animals and also, the detection of genes influencing economically important traits. The purpose of the book is to provide a glimpse into the dynamic process of genetic variation in animals by presenting the thoughts of scientists who are engaged in the generation of new idea and techniques employed for the assessment of genetic diversity, often from very different perspectives. The book should prove useful to students, researchers, and experts in the area of conservation biology, genetic diversity, and molecular biology.

Variation (Biology) --- Biological variation --- Biology --- Heredity --- Genetics --- Mutation (Biology) --- Medical genetics

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

refers to the way in which the environment in the wide sense participates in the regulation of gene expression. This volume is a simplified source of information for both undergraduate and working professionals interested in lifestyle medicine and life sciences in general.

Epigenetics. --- Genetics. --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Genetics

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Since the early eighties, Ali Süleyman Üstünel has been one of the main contributors to the field of Malliavin calculus. In a workshop held in Paris, June 2010 several prominent researchers gave exciting talks in honor of his 60th birthday. The present volume includes scientific contributions from this workshop. Probability theory is first and foremost aimed at solving real-life problems containing randomness. Markov processes are one of the key tools for modeling that plays a vital part concerning such problems. Contributions on inventory control, mutation-selection in genetics and public-private partnerships illustrate several applications in this volume. Stochastic differential equations, be they partial or ordinary, also play a key role in stochastic modeling. Two of the contributions analyze examples that share a focus on probabilistic tools, namely stochastic analysis and stochastic calculus. Three other papers are devoted more to the theoretical development of these aspects. The volume addresses graduate students and researchers interested in stochastic analysis and its applications.

Filters (Mathematics). --- Mathematics. --- Stochastic analysis. --- Stochastic processes. --- Stochastic analysis --- Mathematics --- Physical Sciences & Mathematics --- Mathematical Statistics --- Probabilities --- Differential equations. --- Partial differential equations. --- Probabilities. --- Biomathematics. --- Probability Theory and Stochastic Processes. --- Genetics and Population Dynamics. --- Partial Differential Equations. --- Ordinary Differential Equations. --- Distribution (Probability theory. --- Genetics --- Differential equations, partial. --- Differential Equations. --- 517.91 Differential equations --- Differential equations --- Partial differential equations --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Distribution functions --- Frequency distribution --- Characteristic functions --- Probability --- Statistical inference --- Combinations --- Chance --- Least squares --- Mathematical statistics --- Risk

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book addresses the role of tandem repeat polymorphisms (TRPs) in genetic plasticity, evolution, development, biological processes, neural diversity, brain function, dysfunction and disease. There are hundreds of thousands of unique tandem repeats in the human genome and their polymorphic distributions have the potential to greatly influence functional diversity and disease susceptibility. Recent discoveries in this expanding field are critically reviewed and discussed in a range of subsequent chapters, with a focus on the role of TRPs and their various gene products in evolution, development, diverse molecular and cellular processes, brain function and disease.

Biology. --- Medicine. --- Mutation (Biology). --- Repetitive Sequences, Nucleic Acid --- Genetic Variation --- Genetic Diseases, Inborn --- Neurodegenerative Diseases --- Genome Components --- Biology --- Biological Science Disciplines --- Nervous System Diseases --- Congenital, Hereditary, and Neonatal Diseases and Abnormalities --- Base Sequence --- Genetic Phenomena --- Genome --- Molecular Structure --- Genetic Structures --- Phenomena and Processes --- Diseases --- Natural Science Disciplines --- Disciplines and Occupations --- Biochemical Phenomena --- Chemical Phenomena --- Tandem Repeat Sequences --- Heredodegenerative Disorders, Nervous System --- Polymorphism, Genetic --- Genetics --- Mutation --- Health & Biological Sciences --- Genetic polymorphisms. --- Mutation (Biology) --- Polymorphisms, Genetic --- Medical genetics. --- Neurosciences. --- Biomedicine. --- Biomedicine general. --- Gene Function. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Clinical genetics --- Heredity of disease --- Human genetics --- Pathology --- Genetic disorders --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Physicians --- Genetic aspects --- Variation (Biology) --- Population genetics --- Health Workforce --- Biomedicine, general. --- genetics --- Mutations --- DNA Damage --- Polymorphism, Restriction Fragment Length --- Direct Tandem Repeats --- Tandem Repeat --- Tandem Repeats --- Direct Tandem Repeat --- Repeat Sequence, Tandem --- Repeat Sequences, Tandem --- Repeat, Direct Tandem --- Repeat, Tandem --- Repeats, Direct Tandem --- Repeats, Tandem --- Sequence, Tandem Repeat --- Sequences, Tandem Repeat --- Tandem Repeat Sequence --- Tandem Repeat, Direct --- Tandem Repeats, Direct --- DNA, Concatenated --- Genetic Polymorphisms --- Gene Polymorphism --- Genetic Polymorphism --- Polymorphism (Genetics) --- Gene Polymorphisms --- Polymorphism, Gene --- Polymorphisms (Genetics) --- Polymorphisms, Gene