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2012 (162)

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Book
Microarrays in Diagnostics and Biomarker Development : Current and Future Applications
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ISBN: 9783642282034 Year: 2012 Publisher: Berlin Heidelberg Springer Berlin Heidelberg

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Abstract

Microarray technology has made strong progress over the past decade, and there have also been significant changes in application areas, from nucleic acids to proteomics and from research to clinical applications. This book provides a comprehensive overview of microarrays in diagnostics and biomarker development, covering DNA, peptide, protein and tissue arrays. The focus is on entities that are in actual clinical use, or quite close, and on recent developments, such as peptide and aptamer arrays. A further topic is the miniaturisation towards nanoarrays , which is expected to have great potential in clinical applications. Relevant issues of bioinformatics and statistical analysis of array data are discussed in detail, as well as the barriers to the commercialisation of array-based tests and the vexing IP issues involved. Thus, the book should be very useful tor active array users as well as to newcomers seeking to make the best choice between different technologies.


Digital
Microarrays in Diagnostics and Biomarker Development : Current and Future Applications
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ISBN: 9783642282034 Year: 2012 Publisher: Berlin, Heidelberg Springer Berlin Heidelberg

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Book
Human Cell Transformation : Role of Stem Cells and the Microenvironment
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ISBN: 9781461402541 Year: 2012 Publisher: New York NY Springer New York Imprint Springer

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Book
The Centrosome : Cell and Molecular Mechanisms of Functions and Dysfunctions in Disease
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ISBN: 9781627030359 Year: 2012 Publisher: Totowa NJ Humana Press Imprint Humana Press

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This book features a diversity of aspects on centrosome biology focused on the role of centrosomes in reproduction, cell and molecular biology of centrosomes, centrosome abnormalities in cancer, and centrosomes in various cell systems. Each section contains a variety of different subtopics written by experts in their respective fields who have contributed significant new knowledge to decipher structure and the multiple functions of this still intriguing central organelle. The chapters include comprehensive and concise reviews of key topics in the field as well as cell and molecular details that are important for the specific subtopics. Cutting edge new information is balanced with background information that is readily understandable for the newcomer and the experienced centrosome researcher alike. In addition, several articles will raise awareness of centrosomes in areas that have not yet considered centrosomes associated with disease including aspects of misguided signal transduction and several others that may find centrosomes as new targets for therapeutic intervention. The topics addressed are selected to be of interest to scientists, students, teachers, and to all who are interested in expanding their knowledge related to centrosomes. The book is intended for a large audience as a reference book on the subject.


Book
Notch Signaling in Embryology and Cancer
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ISBN: 9781461408994 Year: 2012 Publisher: New York, NY Springer US

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Digital
Human Cell Transformation : Role of Stem Cells and the Microenvironment
Authors: ---
ISBN: 9781461402541 Year: 2012 Publisher: New York, NY Springer New York

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Digital
Notch Signaling in Embryology and Cancer
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ISBN: 9781461408994 Year: 2012 Publisher: New York, NY Springer US

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Digital
The Centrosome : Cell and Molecular Mechanisms of Functions and Dysfunctions in Disease
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ISBN: 9781627030359 Year: 2012 Publisher: Totowa, NJ Imprint: Humana Press

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Book
Endocrine FGFs and Klothos
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ISBN: 9781461408871 Year: 2012 Publisher: New York, NY Springer US

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Book
Induced Pluripotent Stem Cells
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ISBN: 9781461422068 Year: 2012 Publisher: New York, NY Springer New York

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