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Microarray technology has made strong progress over the past decade, and there have also been significant changes in application areas, from nucleic acids to proteomics and from research to clinical applications. This book provides a comprehensive overview of microarrays in diagnostics and biomarker development, covering DNA, peptide, protein and tissue arrays. The focus is on entities that are in actual clinical use, or quite close, and on recent developments, such as peptide and aptamer arrays. A further topic is the miniaturisation towards nanoarrays , which is expected to have great potential in clinical applications. Relevant issues of bioinformatics and statistical analysis of array data are discussed in detail, as well as the barriers to the commercialisation of array-based tests and the vexing IP issues involved. Thus, the book should be very useful tor active array users as well as to newcomers seeking to make the best choice between different technologies.
Histology. Cytology --- microarrays --- cytologie --- histologie
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Histology. Cytology --- microarrays --- cytologie --- histologie
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Histology. Cytology --- stamcellen --- cytologie --- stamceltransplantatie --- histologie
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This book features a diversity of aspects on centrosome biology focused on the role of centrosomes in reproduction, cell and molecular biology of centrosomes, centrosome abnormalities in cancer, and centrosomes in various cell systems. Each section contains a variety of different subtopics written by experts in their respective fields who have contributed significant new knowledge to decipher structure and the multiple functions of this still intriguing central organelle. The chapters include comprehensive and concise reviews of key topics in the field as well as cell and molecular details that are important for the specific subtopics. Cutting edge new information is balanced with background information that is readily understandable for the newcomer and the experienced centrosome researcher alike. In addition, several articles will raise awareness of centrosomes in areas that have not yet considered centrosomes associated with disease including aspects of misguided signal transduction and several others that may find centrosomes as new targets for therapeutic intervention. The topics addressed are selected to be of interest to scientists, students, teachers, and to all who are interested in expanding their knowledge related to centrosomes. The book is intended for a large audience as a reference book on the subject.
Histology. Cytology --- cytologie --- histologie --- moleculaire biologie
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Histology. Cytology --- Oncology. Neoplasms --- oncologie --- cytologie --- histologie
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Histology. Cytology --- stamcellen --- cytologie --- stamceltransplantatie --- histologie
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Histology. Cytology --- Oncology. Neoplasms --- oncologie --- cytologie --- histologie
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Histology. Cytology --- cytologie --- histologie --- moleculaire biologie
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Genetics --- Histology. Cytology --- Molecular biology --- cytologie --- histologie --- moleculaire biologie --- genexpressie
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Histology. Cytology --- Biotechnology --- stamcellen --- biotechnologie --- cytologie --- stamceltransplantatie --- histologie
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