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2013 (3)

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Book
Functional Connections of Cortical Areas : a New View from the Thalamus
Authors: ---
ISBN: 0262314991 0262019302 1299773273 0262315009 9781461937111 1461937116 9780262314992 9781299773271 9780262019309 Year: 2013 Publisher: Cambridge, Mass. : MIT Press,

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Abstract

This study shows new ways of thinking about how the brain relates to the world, to cognition, and to behaviour. Based on foundations previously established it considers the implications of these ground rules for thalamic inputs, thalamocortical connections, and cortical outputs. The book argues that functional and structural analyses of pathways connecting thalamus and cortex point beyond these to lower centres and through them to the body and the world.


Book
Microstructural Parcellation of the Human Cerebral Cortex : From Brodmann's Post-Mortem Map to in Vivo Mapping with High-Field Magnetic Resonance Imaging
Authors: ---
ISBN: 3642430767 3642378234 3642378242 Year: 2013 Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,

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Unraveling the functional properties of structural elements in the brain is one of the fundamental goals of neuroscientific research. In the cerebral cortex this is no mean feat, since cortical areas are defined microstructurally in post-mortem brains but functionally in living brains with electrophysiological or neuroimaging techniques – and cortical areas vary in their topographical properties across individual brains. Being able to map both microstructure and function in the same brains noninvasively in vivo would represent a huge leap forward. In recent years, high-field magnetic resonance imaging (MRI) technologies with spatial resolution below 0.5 mm have set the stage for this by detecting structural differences within the human cerebral cortex, beyond the Stria of Gennari. This provides the basis for an in vivo microanatomical brain map, with the enormous potential to make direct correlations between microstructure and function in living human brains. This book starts with Brodmann’s post-mortem map published in the early 20th century, moves on to the almost forgotten microstructural maps of von Economo and Koskinas and the Vogt-Vogt school, sheds some light on more recent approaches that aim at mapping cortical areas noninvasively in living human brains, and culminates with the concept of “in vivo Brodmann mapping” using high-field MRI, which was introduced in the early 21st century.


Book
Cortical Development : Neural Diversity and Neocortical Organization
Authors: ---
ISBN: 443154495X 4431544968 Year: 2013 Publisher: Tokyo : Springer Japan : Imprint: Springer,

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This book reviews recent progress in cortical development research, focusing on the mechanisms of neural stem cell regulation, neuronal diversity and connectivity formation, and neocortical organization. Development of the cerebral cortex, the center for higher brain functions such as cognition, memory, and decision making, is one of the major targets of current research. The cerebral cortex is divided into many areas, including motor, sensory, and visual cortices, each of which consists of six layers containing a variety of neurons with different activities and connections. As this book explains, such diversity in neuronal types and connections is generated at various levels. First, neural stem cells change their competency over time, giving sequential rise to distinct types of neurons and glial cells: initially deep layer neurons, then superficial layer neurons, and lastly astrocytes. The activities and connections of neurons are further modulated via interactions with other brain regions, such as the thalamocortical circuit, and via input from the environment. This book on cortical development is essential reading for students, postdocs, and neurobiologists.

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