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This complete, yet concise, guide introduces you to the rapidly developing field of high throughput screening of biomaterials: materiomics. Bringing together the key concepts and methodologies used to determine biomaterial properties, you will understand the adaptation and application of materomics in areas such as rapid prototyping, lithography and combinatorial chemistry. Each chapter is written by internationally renowned experts, and includes tutorial paragraphs on topics such as biomaterial-banking, imaging, assay development, translational aspects, and informatics. Case studies of state-of-the-art experiments provide illustrative examples, whilst lists of key publications allow you to easily read up on the most relevant background material. Whether you are a professional scientist in industry, a student or a researcher, this book is not to be missed if you are interested in the latest developments in biomaterials research.
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Drug development. --- Development of drugs --- Drugs --- New drug development --- Pharmacology --- Pharmacy --- Development
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A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide that outlines day-to-day activities and experiences in preclinical toxicology. This multi-contributed reference provides a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules
Ethics and addiction --- Drug development. --- Development of drugs --- Drugs --- New drug development --- Pharmacology --- Pharmacy --- Development
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The purpose of Ligand Efficiency Indices for Drug Discovery: Towards an Atlas-Guided Paradigm is to introduce in a concise and self-contained form the concepts, ideas, applications and examples of efficiency-driven drug discovery to the biomedical community at large. The book emphasizes the use of 'new variables' and more objective numerical methods to drive drug discovery in an encompassing way. These 'new variables' are based on Ligand Efficiency Indices (LEIs) formulated in a way that permits mapping Chemico-Biological Space (CBS) in an Atlas-like representation. It provide
Ethics and addiction --- Drug development. --- Development of drugs --- Drugs --- New drug development --- Pharmacology --- Pharmacy --- Development
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Pharmaceutical Preparations --- Drug Design. --- Models, Molecular. --- Drug development. --- Drug development. --- Médicaments --- chemical synthesis. --- Développement
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The breadth of the pharmaceutical medicine can be daunting, but this book is designed to navigate a path through the speciality. Providing a broad overview of all topics relevant to the discipline of pharmaceutical medicine, it gives you the facts fast, in a user-friendly format, without having to dive through page upon page of dense text. With 136 chapters spread across 8 sections, the text offers a thorough grounding in issues ranging from medicines regulation to clinical trial design and data management. This makes it a useful revision aid for exams as well as giving you a taster of areas o
Clinical pharmacology. --- Drug development. --- Drugs --- Pharmaceutical research --- Pharmacology --- Development of drugs --- New drug development --- Pharmacy --- Clinical medicine --- Research. --- Research --- Development
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Lead Compounds from Medicinal Plants for the Treatment of Cancer is the first volume in the series, Pharmaceutical Leads from Medicinal Plants. The plant species described in this reference have been carefully selected based on pharmacological evidence and represent today's most promising sources of natural products for the discovery of anti-cancer drugs. Containing references to primary source material, over a hundred botanical illustrations, a table of chemical structures and much more, this book is an essential starting point for cancer researchers and those involved in anti-cancer drug
Drugs --- Drug development. --- Pharmaceutical chemistry. --- Chemotherapy. --- Design. --- Drug therapy --- Pharmacotherapy --- Therapeutics --- Pharmacology --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry --- Development of drugs --- New drug development --- Pharmacy --- Drug design --- Pharmaceutical design --- Drug development --- Development
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Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment combines the experience of academic, clinical and industrial neuroimagers in a unique collaborative approach to provide an integrated perspective of the use of small animal and human brain imaging in developing and validating translational models and biomarkers for the study and treatment of neuropsychiatric disorders. Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment examines the translational role of neuroimaging in model development from preclinical animal m
Central nervous system --- Neuropsychopharmacology. --- Drug development. --- Imaging. --- Diseases --- Diagnosis. --- Development of drugs --- Drugs --- New drug development --- Pharmacology --- Pharmacy --- Neuro-psychopharmacology --- Neuropharmacology --- Psychopharmacology --- Nervous system, Central --- Nervous system --- Development
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The Path from Biomarker Discovery to Regulatory Qualification is a unique guide that focuses on biomarker qualification, its history and current regulatory settings in both the US and abroad. This multi-contributed book provides a detailed look at the next step to developing biomarkers for clinical use and covers overall concepts, challenges, strategies and solutions based on the experiences of regulatory authorities and scientists. Members of the regulatory, pharmaceutical and biomarker development communities will benefit the most from using this book-it is a complete and pr
Biomarker. --- Medicine. --- Pharmaceutical industry. --- Biochemical markers --- Drug Discovery --- Biological Markers --- Chemistry, Pharmaceutical --- Investigative Techniques --- Biological Factors --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Chemistry --- Pharmacology --- Chemicals and Drugs --- Natural Science Disciplines --- Biological Science Disciplines --- Disciplines and Occupations --- Biomarkers, Pharmacological --- Drug Design --- Biology --- Medicine --- Health & Biological Sciences --- Medical Research --- Genetics --- Biochemical markers. --- Drug development. --- Drugs --- Design. --- Drug design --- Pharmaceutical design --- Drug development --- Development of drugs --- New drug development --- Pharmacy --- Biologic markers --- Biological markers --- Biomarkers --- Markers, Biochemical --- Biochemistry --- Indicators (Biology) --- Development
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Introduction to Biological and Small Molecule Drug Research and Development provides, for the first time, an introduction to the science behind successful pharmaceutical research and development programs. The book explains basic principles, then compares and contrasts approaches to both biopharmaceuticals (proteins) and small molecule drugs, presenting an overview of the business and management issues of these approaches. The latter part of the book provides carefully selected real-life case studies illustrating how the theory presented in the first part of the book is actually put i
Drugs -- Research. --- Medicine -- Research. --- Pharmacology. --- Pharmacy. --- Drug development --- Biopharmaceutics --- Investigative Techniques --- Pharmacology --- Chemistry, Pharmaceutical --- Laboratory Chemicals --- Chemistry --- Specialty Uses of Chemicals --- Health Occupations --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Biological Science Disciplines --- Natural Science Disciplines --- Disciplines and Occupations --- Chemical Actions and Uses --- Chemicals and Drugs --- Methods --- Drug Discovery --- Small Molecule Libraries --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Drug development. --- Development of drugs --- Drugs --- New drug development --- Development --- Pharmacy --- Biopharmaceutics.
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