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Book
MicroRNA cancer regulation : advanced concepts, bioinformatics and systems biology tools
Authors: --- ---
ISBN: 9400755899 9400755902 129940765X Year: 2013 Publisher: Dordrecht ; London : Springer,

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Abstract

This book reflects the current state of knowledge about the role of microRNAs in the formation and progression of solid tumours. The main focus lies on computational methods and their applications in combination with cutting edge experimental techniques that are used to approach all aspects of microRNA regulation in cancer. The use of high-throughput quantitative techniques makes an integrative experimental and computational approach necessary. This book will be a resource for researchers starting out with microRNA research, but is also intended for the experienced researcher who wants to incorporate concepts and tools from systems biology and bioinformatics into his work. Bioinformaticians and modellers are provided with a general perspective on microRNA biology, and the state-of-the-art in computational microRNA biology.

Keywords

Cancer -- Genetic aspects. --- Cancer. --- MicroRNA. --- Small interfering RNA --- Cancer --- Genomics --- Bioinformatics --- Biology --- Diseases --- Biochemical Processes --- RNA, Antisense --- Genetic Techniques --- Gene Expression Regulation --- Investigative Techniques --- Biological Science Disciplines --- Genetic Processes --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Biochemical Phenomena --- Antisense Elements (Genetics) --- Natural Science Disciplines --- Chemical Phenomena --- Nucleic Acids, Nucleotides, and Nucleosides --- Genetic Phenomena --- Phenomena and Processes --- Disciplines and Occupations --- Chemicals and Drugs --- Signal Transduction --- MicroRNAs --- Neoplasms --- Methods --- Gene Expression Profiling --- Computational Biology --- Gene Expression Regulation, Neoplastic --- Genetics --- Medicine --- Health & Biological Sciences --- Oncology --- Research --- Genetic aspects --- Data processing --- Bioinformatics. --- Research. --- Data processing. --- Bio-informatics --- Biological informatics --- Genome research --- Genomes --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- piRNA (Piwi-interacting RNA) --- Piwi-interacting RNA --- Piwi protein-interacting RNA --- rasiRNA (Repeat-associated small interfering RNA) --- Repeat-associated siRNA --- Repeat-associated small interfering RNA --- Scan RNA --- scnRNA (Small scan RNA) --- Short hairpin RNA --- Short interfering RNA --- shRNA (Short hairpin RNA) --- siRNA (Small interfering RNA) --- Small hairpin RNA --- Small scan RNA --- tasiRNA (Trans-acting small interfering RNA) --- Trans-acting siRNA --- Trans-acting small interfering RNA --- Medicine. --- Cancer research. --- Gene expression. --- Molecular biology. --- Systems biology. --- Biomedicine. --- Cancer Research. --- Computational Biology/Bioinformatics. --- Systems Biology. --- Molecular Medicine. --- Gene Expression. --- Information science --- Computational biology --- Systems biology --- Biological systems --- Molecular biology --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Genes --- Genetic regulation --- Cancer research --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Expression --- Molecular genetics --- Tumors --- Antisense RNA --- Oncology. --- Biological models. --- Models, Biological

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