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Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry. This volume continues in the serial's tradition of providing an insight into the skills required of the modern medicinal chemist; in particular, the use of an appropriate selection of the wide range of tools now available to solve key scientific problems, including g-secretase modulators, P2X7 antagonists as therapeutic agents for CNS disorders, N-type calcium channel modulators for the treatment of pain, and more.Extended timely reviews of topics in me
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Originally published by Bentham and now distributed by Elsevier, Recent Advances in Medicinal Chemistry, Volume 1 covers leading-edge research and recent developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The fourteen updated reviews include unique experimental data and references, and each article highlights an important topic in current medicinal chemistry research. Topics covered include: aureolic acid group of anti-cancer
Pharmaceutical chemistry. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry
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Recent advances in Medicinal Chemistry is a book series focused on leading-edge research on developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The series presents highly cited contributions first published in the impact factor journal Mini-Reviews in Medicinal Chemistry. Contributors to this volume have updated their work with new experimental data and references following their initial research. Each volume highlights a numbe
Pharmaceutical chemistry. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry
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The physician and author John Ayrton Paris (1785-1856), several of whose other medical and popular works have been reissued in the Cambridge Library Collection, published the first edition of his Pharmacologia in 1812. It was immediately successful, and went into eight further editions until 1843. The third edition, of 1820, has been reissued in this series. This book, published in 1825, was intended as a companion volume, providing a 'grammar' of chemistry for the medical student. After an imaginary dialogue on the importance of chemistry, between a provincial physician and 'the author', to whom the former is entrusting his son for his medical education, the book moves systematically from the general application of chemistry to medicine, through topics such as gravity, crystallization and electricity, to the detail of the actions of specific elements, and tables of relevant weights and measures, providing fascinating insights into the history of medical education.
Pharmaceutical chemistry. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry
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This book is useful to readers who are just beginning in the field of drug design and development. It starts with an introduction and some basic information about drugs. Pharmacokinetic and pharmacodynamic aspects are covered in the initial chapters. Systemic descriptions of pharmacokinetic parameters such as absorption, distribution, metabolism, and excretion are explained in simple and easy language. This book demonstrates detailed concepts of lead molecules and their sources. In addition, drug target classification, identification and validation strategies, as well as the design and develop
Drugs --- Pharmaceutical chemistry. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry --- Pharmaceutical research --- Pharmacology --- Research. --- Research
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DNA-drug interactions --- Ligand binding (Biochemistry) --- Drugs --- Pharmaceutical chemistry. --- Interactions ADN-médicaments --- Ligands (Biochimie) --- Médicaments --- Chimie pharmaceutique --- Design. --- Fixation --- Conception
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Pharmacology. Therapy --- Chemie [Farmaceutische ] --- Chemistry [Medical and pharmaceutical ] --- Chemistry [Pharmaceutical ] --- Chimie pharmaceutique --- Drug chemistry --- Drugs--Chemistry --- Farmaceutische chemie --- Medical chemistry --- Medicinal chemistry --- Pharmaceutical chemistry --- Pharmacochemistry --- Drugs --- Standards --- Congresses --- Technology
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Pharmeceutical drug discovery has wide-reaching and obvious effects on the lives of people everywhere, and yet the general public knows very little about the way in which these important products are conceived. We rely on pharmaceuticals to keep us healthy in countless ways, with almost no understanding of the process behind the creation of the drugs we use. In this book, Eugene Cordes reveals just how some of the most important and influential drugs are made. He shares his firsthand knowledge of the drug-discovery world, having spent a long and distinguished career on both the academic and industrial side of pharmaceutical research.
Drug development --- Development of drugs --- Drugs --- New drug development --- Pharmacology --- Pharmacy --- History. --- Development --- Pharmaceutical chemistry. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry --- Pharmaceutical research --- Research. --- Research
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Pharmaceutical chemistry. --- Bioorganic chemistry. --- Molecular pharmacology. --- Drugs --- Chemistry, Pharmaceutical. --- Chemistry, Organic. --- Drug Design. --- Pharmacokinetics. --- Pharmaceutical chemistry --- Bioorganic chemistry --- Molecular pharmacology --- Drug Discovery --- Metabolic Phenomena --- Kinetics --- Pharmacology --- Chemistry --- Pharmacological Phenomena --- Investigative Techniques --- Phenomena and Processes --- Natural Science Disciplines --- Biochemical Phenomena --- Biological Science Disciplines --- Physiological Phenomena --- Disciplines and Occupations --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Chemical Phenomena --- Drug Design --- Pharmacokinetics --- Chemistry, Organic --- Chemistry, Pharmaceutical --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Design. --- Design --- Drug design --- Pharmaceutical design --- Drug development --- Molecular biology --- Bio-organic chemistry --- Biological organic chemistry --- Biochemistry --- Chemistry, Medical and pharmaceutical --- Drug chemistry --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Drugs - Design
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Attention has recently turned to using plants as hosts for the production of commercially important proteins. The twelve case studies in this volume present successful strategies for using plants to produce industrial and pharmaceutical proteins and vaccine antigens. They examine in detail projects that have commercial potential or products that have already been commercialized, illustrating the advantages that plants offer over bacterial, fungal or animal cell-culture hosts. There are many indications that plant protein production marks the beginning of a new paradigm for the commercial production of proteins that, over the next decade, will expand dramatically.
Recombinant proteins. --- Plant biotechnology. --- Genetically engineered proteins --- Proteins --- Recombinant molecules --- Crop biotechnology --- Crops --- Plants --- Agricultural biotechnology --- Genetic engineering --- Biotechnology --- Plant breeding. --- Biotechnology. --- Pharmaceutical technology. --- Plant Breeding/Biotechnology. --- Pharmaceutical Sciences/Technology. --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Technology --- Chemical engineering --- Agriculture --- Breeding --- Pharmaceutical chemistry. --- Plant Biotechnology. --- Pharmaceutics. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry
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