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Genetic regulation. --- Epigenetics. --- Genetics --- Gene expression --- Gene expression regulation --- Gene regulation --- Biosynthesis --- Cellular control mechanisms --- Molecular genetics --- Regulation --- Epigenesis, Genetic. --- Epigenetic Process --- Epigenetics Processes --- Epigenetic Processes --- Genetic Epigenesis --- Process, Epigenetic --- Processes, Epigenetic --- Processes, Epigenetics --- Epigenome --- DNA Methylation

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This volume explores the epigenetic alterations and their association with various human cancers. Considering one of human cancer as an example, individual chapters are focused on defining the role of epigenetic regulators and underlying mechanisms in cancer growth and progression.   Epigenetic alteration including DNA methylation, histone modification, nucleosome positioning and non-coding RNAs expression are involved in a complex network of regulating expression of oncogenes and tumor suppressor genes and constitute an important event of the multistep process of carcinogenesis. Recent advances in the understanding of the epigenetic regulation and detailed information of these epigenetic changes in various cancers provide new avenues of advancements in diagnostics, prognostics, and therapies of this highly fatal disease.

Gene expression. --- Cancer --- Epigenetics. --- Genetic aspects. --- Cancer genetics --- Genetics --- Cancer genes --- Oncology. --- Cancer Research. --- Gene Expression. --- Genes --- Genetic regulation --- Tumors --- Expression --- Neoplasms --- Epigenesis, Genetic. --- genetics. --- Epigenetic Process --- Epigenetics Processes --- Epigenetic Processes --- Genetic Epigenesis --- Process, Epigenetic --- Processes, Epigenetic --- Processes, Epigenetics --- Epigenome --- DNA Methylation --- Cancer research. --- Cancer research

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"Epigenetics, a new field in biology, has shown that in some instances organisms can inherit characteristics acquired by their ancestors during their lifetimes, a view that was discredited during most of the twentieth century. Trofim Lysenko, a Russian agronomist long considered a charlatan, was a strong advocate of the inheritance of acquired characteristics. In the last few years a number of Russian science writers and scientists have claimed that epigenetics proves that Lysenko was right after all. This book evaluates that claim."--Provided by publisher. Lysenko became one of the most notorious figures in twentieth-century science after his genetic theories were discredited decades ago. Yet some scientists now claim that discoveries in epigenetics prove that he was right after all. Loren Graham reopens the case, to determine whether new developments in molecular biology validate Lysenko’s claims.

Epigenetics --- Epigenomics --- Epigenesis, Genetic. --- Genetic Research --- History, 20th Century. --- History, 21st Century. --- Genetics --- 21st Cent. History (Medicine) --- 21st Cent. History of Medicine --- 21st Cent. Medicine --- Historical Events, 21st Century --- History of Medicine, 21st Cent. --- History, Twenty-first Century --- Medical History, 21st Cent. --- Medicine, 21st Cent. --- 21st Century History --- 21st Cent. Histories (Medicine) --- 21st Cent. Medicines --- 21st Century Histories --- Cent. Histories, 21st (Medicine) --- Cent. History, 21st (Medicine) --- Cent. Medicine, 21st --- Cent. Medicines, 21st --- Century Histories, 21st --- Century Histories, Twenty-first --- Century History, 21st --- Century History, Twenty-first --- Histories, 21st Cent. (Medicine) --- Histories, 21st Century --- Histories, Twenty-first Century --- History, 21st Cent. (Medicine) --- History, Twenty first Century --- Medicines, 21st Cent. --- Twenty-first Century Histories --- Twenty-first Century History --- 20th Cent. History (Medicine) --- 20th Cent. History of Medicine --- 20th Cent. Medicine --- Historical Events, 20th Century --- History of Medicine, 20th Cent. --- History, Twentieth Century --- Medical History, 20th Cent. --- Medicine, 20th Cent. --- 20th Century History --- 20th Cent. Histories (Medicine) --- 20th Century Histories --- Cent. Histories, 20th (Medicine) --- Cent. History, 20th (Medicine) --- Century Histories, 20th --- Century Histories, Twentieth --- Century History, 20th --- Century History, Twentieth --- Histories, 20th Cent. (Medicine) --- Histories, 20th Century --- Histories, Twentieth Century --- History, 20th Cent. (Medicine) --- Twentieth Century Histories --- Twentieth Century History --- Epigenetic Process --- Epigenetics Processes --- Epigenetic Processes --- Genetic Epigenesis --- Process, Epigenetic --- Processes, Epigenetic --- Processes, Epigenetics --- Epigenome --- DNA Methylation --- history. --- Lysenko, Trofim, --- Lysenko, Trofim Denisovich, --- Lisenko, T. D. --- Lysenko, Trokhym Denysovych, --- Lyssenko, Trofim Denissowitsch, --- Lyssenko, Trophim, --- Lysenko, T. D. --- Лысенко, Трофим, --- Лысенко, Трофим Денисович, --- ליסנקו, ט. ד., --- USSR. --- Russia. --- Russian Federation (Europe) --- Russian SFSR --- Russian S.F.S.R. --- Soviet Union --- Union of Soviet Socialist Republics