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Prothrombin --- Factor II --- Plasmozyme --- Prothrombase --- Thrombogen --- Thrombogenin --- Blood proteins --- Glycoproteins --- Research.

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This book describes the newest developments in antibody drug conjugates and immunotoxins, paving their way to clinical application. Lessons learned from the current state of the art are used to further improve our understanding of their mechanisms of action and off target activities. The book introduces scientists to all of the prerequisites that must be properly addressed, including identification of the right target, specific traits of target binding antibodies, proper selection of the toxic payload, internalization induced by binding, and next generation conjugation and linker technologies. These knowledge-based, revolutionary new drug principles will form the cornerstone of the future standard of care and will lead to major advances in application, as well as improved quality of life and patient survival rates. This book will be of interest to biotech companies and researchers working in the fields of immunology, pharmacology, and oncology.

Medicine. --- Cancer research. --- Antibodies. --- Pharmacology. --- Oncology. --- Pharmacotherapy. --- Biomedicine. --- Pharmacology/Toxicology. --- Cancer Research. --- Antibody-toxin conjugates. --- Conjugates, Antibody-toxin --- Immunoconjugates --- Immunoglobulin-toxin conjugates --- Immunotoxins --- Toxin-antibody conjugates --- Toxin-immunoglobulin conjugates --- Bioconjugates --- Immunopharmacology --- Immunotoxicology --- Toxins --- Toxicology. --- Monoclonal antibodies. --- Oncology  . --- Tumors --- Antibodies, Monoclonal --- Monoclonal immunoglobulins --- Immunoglobulins --- Molecular cloning --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Toxicology --- Cancer research --- Drug therapy --- Pharmacotherapy --- Therapeutics --- Drugs --- Antibodies --- Immune globulins --- Immune serum globulin --- Blood proteins --- Globulins --- Plasma cells --- Antibody diversity --- Antigens --- Bacterial immunoglobulin-binding proteins --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Pharmacy --- Physiological effect

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There are many principles and applications of recombinant antibodies for infectious diseases. The preferred technology associated to recombinant antibody generation is mainly phage display. The adaptation of antibodies for infectious diseases is an area lacking information as most literature is focused on oncology or autoimmunity. This project highlights the power and potential of antibody phage display for infectious diseases. In addition to that, supplementary information regarding technologies associated to antibody generation and engineering in the context of infectious disease will also help to provide greater insight to the potential of recombinant antibodies for infectious diseases.

Recombinant antibodies. --- Communicable diseases. --- Medicine. --- Antibodies. --- Infectious diseases. --- Biomedicine. --- Infectious Diseases. --- Antibodies --- Immune globulins --- Immune serum globulin --- Blood proteins --- Globulins --- Plasma cells --- Antibody diversity --- Antigens --- Bacterial immunoglobulin-binding proteins --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Contagion and contagious diseases --- Contagious diseases --- Infectious diseases --- Microbial diseases in human beings --- Zymotic diseases --- Diseases --- Infection --- Epidemics --- Genetically engineered antibodies --- Recombinant immunoglobulins --- Immunoglobulins --- Recombinant proteins --- Monoclonal antibodies. --- Emerging infectious diseases. --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Antibodies, Monoclonal --- Monoclonal immunoglobulins --- Molecular cloning