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The atomic structures of macromolecules provide the key to understanding how life works. Aaron Klug led the way in the development of methods for solving such structures and is one of the pioneers of structural molecular biology. He was awarded a Nobel Prize in 1982 for his work. Illuminating both his personal life and scientific achievements, this unique biography begins with Klug's youth in Durban and his studies at Johannesburg, Cape Town and then Trinity College, Cambridge. Holmes proceeds to explore Klug's career from his work on the structure of viruses with Rosalind Franklin at Birkbeck College, London to his time as Director of the MRC Laboratory of Molecular Biology (LMB) in Cambridge and as President of the Royal Society. Drawing on their long-term collaboration, interviews and unique access to Klug's archives, Holmes provides a fascinating account of an innovative man and his place in the history of structural molecular biology.
Chemists --- Biophysicists --- Biological physicists --- Biologists --- Physicists --- Klug, A. --- Klug, Aaron,
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How does life work? How does nature produce the right numbers of zebras and lions on the African savanna, or fish in the ocean? How do our bodies produce the right numbers of cells in our organs and bloodstream? In The Serengeti Rules, award-winning biologist and author Sean Carroll tells the stories of the pioneering scientists who sought the answers to such simple yet profoundly important questions, and shows how their discoveries matter for our health and the health of the planet we depend upon.One of the most important revelations about the natural world is that everything is regulated-there are rules that regulate the amount of every molecule in our bodies and rules that govern the numbers of every animal and plant in the wild. And the most surprising revelation about the rules that regulate life at such different scales is that they are remarkably similar-there is a common underlying logic of life. Carroll recounts how our deep knowledge of the rules and logic of the human body has spurred the advent of revolutionary life-saving medicines, and makes the compelling case that it is now time to use the Serengeti Rules to heal our ailing planet.A bold and inspiring synthesis by one of our most accomplished biologists and gifted storytellers, The Serengeti Rules is the first book to illuminate how life works at vastly different scales. Read it and you will never look at the world the same way again.
Life (Biology) --- Biological control systems. --- Nature --- Ecology. --- Biology --- Biologists --- Effect of human beings on. --- Research
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Inspired by the Research Collaboration Workshop for Women in Mathematical Biology, this volume contains research and review articles that cover topics ranging from models of animal movement to the flow of blood cells in the embryonic heart. Hosted by the National Institute for Mathematics and Biological Synthesis (NIMBioS), the workshop brought together women working in biology and mathematics to form four research groups that encouraged multidisciplinary collaboration and lifetime connections in the STEM field. This volume introduces many of the topics from the workshop, including the aerodynamics of spider ballooning; sleep, circadian rhythms, and pain; blood flow regulation in the kidney; and the effects of antimicrobial therapy on gut microbiota and microbiota and Clostridium difficile. Perfect for students and researchers in mathematics and biology, the papers included in this volume offer an introductory glimpse at recent research in mathematical biology. .
Mathematics. --- Mathematical models. --- Biomathematics. --- Physiological, Cellular and Medical Topics. --- Mathematical Modeling and Industrial Mathematics. --- Biology --- Women biologists. --- Biologists --- Women life scientists --- Biological models --- Biomathematics --- Physiology --- Animal physiology --- Animals --- Anatomy --- Models, Mathematical --- Simulation methods --- Mathematics
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"Over the centuries, natural history museums have evolved from being little more than musty repositories of stuffed animals and pinned bugs, to being crucial generators of new scientific knowledge. They have also become vibrant educational centers, full of engaging exhibits that share those discoveries with students and an enthusiastic general public. At the heart of it all from the very start have been curators. Yet after three decades as a natural history curator, Lance Grande found that he still had to explain to people what he does. This book is the answer - and, oh, what an answer it is: lively, exciting, up-to-date, it offers a portrait of curators and their research like none we've seen, one that conveys the intellectual excitement and the educational and social value of curation. Grande uses the personal story of his own career - most of it spent at Chicago's storied Field Museum - to structure his account as he explores the value of research and collections, the importance of public engagement, changing ecological and ethical considerations, and the impact of rapidly improving technology. Throughout, we are guided by Grande's keen sense of mission, of a job where the why is always as important as the what. This beautifully written and richly illustrated book is a clear-eyed but loving account of natural history museums, their curators, and their ever-expanding roles in the twenty-first century"--Publisher. Natural history museums have evolved from being little more than musty repositories of stuffed animals and pinned bugs, to being crucial generators of new scientific knowledge. They have also become vibrant educational centers, full of engaging exhibits that share those discoveries with students and an enthusiastic general public. Grande offers a portrait of curators and their research, conveying the intellectual excitement and the educational and social value of curation. He uses the personal story of his own career-- most of it spent at Chicago's Field Museum-- to explore the value of research and collections, the importance of public engagement, changing ecological and ethical considerations, and the impact of rapidly improving technology.
Natural history museum curators --- Biologists --- Paleontologists --- Natural history museum curators --- Curatorship --- Natural history museums --- Grande, Lance. --- Field Museum of Natural History
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In this Brief, Joe Jeffers uncovers the life and works of two-time Nobel Laureate Frederick Sanger. Following Sanger’s early life to retirement, Jeffers describes how this celebrated British biochemist became the first person to determine the amino acid sequence of a protein for which he was awarded the Nobel Prize in 1958. Highlighting Sanger’s remarkable career, Jeffers describes Sanger’s later change in research direction to investigate deoxyribonucleic acids (DNA), work for which Sanger also received the Nobel Prize jointly with Paul Berg and Walter Gilbert in 1980. Joe Jeffers conducted twelve interviews with Sanger over the period of 1999-2009 and he has also spoken to more than 40 of Sanger’s colleagues and family members. This brief provides a rigorous yet concise view of Sanger on a personal and scientific level and is suitable for biochemists, historians or the interested layperson.
Biochemists --- Sanger, Frederick, --- Biological chemists --- Chemistry. --- History. --- Bioorganic chemistry. --- Proteins. --- Bioorganic Chemistry. --- History of Science. --- Protein Science. --- Biologists --- Chemists --- Biochemistry. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Annals --- Auxiliary sciences of history --- Bio-organic chemistry --- Biological organic chemistry --- Biochemistry --- Chemistry, Organic --- Composition --- Proteins . --- Proteids --- Biomolecules --- Polypeptides --- Proteomics
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Over the centuries, natural history museums have evolved from being little more than musty repositories of stuffed animals and pinned bugs, to being crucial generators of new scientific knowledge. They have also become vibrant educational centers, full of engaging exhibits that share those discoveries with students and an enthusiastic general public. At the heart of it all from the very start have been curators. Yet after three decades as a natural history curator, Lance Grande found that he still had to explain to people what he does. This book is the answer—and, oh, what an answer it is: lively, exciting, up-to-date, it offers a portrait of curators and their research like none we’ve seen, one that conveys the intellectual excitement and the educational and social value of curation. Grande uses the personal story of his own career—most of it spent at Chicago’s storied Field Museum—to structure his account as he explores the value of research and collections, the importance of public engagement, changing ecological and ethical considerations, and the impact of rapidly improving technology. Throughout, we are guided by Grande’s keen sense of mission, of a job where the why is always as important as the what. This beautifully written and richly illustrated book is a clear-eyed but loving account of natural history museums, their curators, and their ever-expanding roles in the twenty-first century.
Natural history museum curators --- Biologists --- Paleontologists --- Natural history museum curators. --- Curatorship. --- Natural history museums. --- Grande, Lance. --- Field Museum of Natural History --- administration and management. --- basic vs applied research. --- biodiversity. --- collection-based research. --- curators. --- education. --- evolution. --- exploration and fieldwork. --- natural history museums. --- science literacy.
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This book is an informal autobiography by John West MD PhD. He obtained his medical degree in Adelaide, Australia and then spent 15 years mainly at the Royal Postgraduate Medical School, Hammersmith Hospital in London where he, with others, used radioactive oxygen-15 to make the first description of the uneven regional distribution of blood flow in the lung. In 1960-1961, he was a member of the Himalayan Scientific and Mountaineering Expedition led by Sir Edmund Hillary who had made the first ascent of Mt Everest 7 years before. During the expedition about 6 scientists spent up to three months at an altitude of 5800 m studying the effects of this very high altitude on human physiology. Because of his interests in the effects of gravity on the lung, Dr. West spent a year at the NASA Ames Research Center in Mountain View, California in 1967-1968. While there he submitted a proposal to NASA to measure pulmonary function of astronauts in space, and this was funded. Later, in 1981 he organized the American Medical Research Expedition to Everest during which the first measurements of human physiology on the summit, altitude 8848 m, were obtained. In the 1990’s, Dr. West’s team made the first comprehensive measurements of pulmonary function of astronauts in space using SpaceLab which was taken up in the Shuttle.
Medicine. --- History. --- Human physiology. --- Respiratory organs --- Sports sciences. --- Biomedicine. --- Human Physiology. --- History of Science. --- Sport Science. --- Pneumology/Respiratory System. --- Space Sciences (including Extraterrestrial Physics, Space Exploration and Astronautics). --- Diseases. --- Pneumology. --- Astrophysics. --- Sport Science . --- Human biology --- Medical sciences --- Physiology --- Human body --- Annals --- Auxiliary sciences of history --- Astronomical physics --- Astronomy --- Cosmic physics --- Physics --- Physiologists --- Physiology. --- West, John B. --- Air passages (Anatomy) --- Respiratory system --- Cardiopulmonary system --- Biologists --- Medical scientists --- West, John Burnard --- West, J. B. --- Respiratory organs—Diseases. --- Space sciences. --- Sciences, Sports --- Sport sciences --- Physical education and training --- Science --- Science and space --- Space research --- Cosmology
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In this fascinating study, Samantha George explores the cultivation of the female mind and the feminised discourse of botanical literature in eighteenth-century Britain. In particular, she discusses British women's engagement with the Swedish botanist, Carl Linnaeus, and his unsettling discovery of plant sexuality. Previously ignored primary texts of an extraordinary nature are rescued from obscurity and assigned a proper place in the histories of science, eighteenth-century literature, and women's writing. The result is groundbreaking: the author explores nationality and sexuality debates in relation to botany and charts the appearance of a new literary stereotype, the sexually precocious female botanist. She uncovers an anonymous poem on Linnaean botany, handwritten in the eighteenth century, and subsequently traces the development of a new genre of women's writing - the botanical poem with scientific notes. The book is indispensable reading for all scholars of the eighteenth century, especially those interested in Romantic women's writing, or the relationship between literature and science.
Plants, Sex in --- Women botanists --- Botany in literature --- Botanical literature --- Biological literature --- Botany --- Botanists --- Women biologists --- Women in botany --- Sex in plants --- Plant physiology --- Sex (Biology) --- Plants --- History --- Women authors --- Reproduction --- Linne, Carl von, --- Influence. --- Linné, Carl von, --- Linnaeus, Carl, --- Linneĭ, Karl, --- Linnaeus, Carolus, --- Von Linné, Carl, --- Linnaeus, C., --- Linneus, --- Linné, Carolus a, --- Linné, Charles, --- Lineu, Carlos, --- Plants, Sex in. --- Literature --- Literary Theory --- LITERARY CRITICISM / European / English, Irish, Scottish, Welsh` --- Ireland --- Authorship --- History and criticism. --- British women's engagement. --- Carl Linnaeus. --- Collinsonia. --- Erasmus Darwin. --- Linnaean Sexual System. --- Linnaean classification. --- Mary Wollstonecraft. --- botanical classification. --- botanical literature. --- eighteenth-century Britain. --- female mind. --- female modesty. --- floristry. --- plant sexuality. --- sexual anxiety.
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