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Biochemical markers. --- Immunochemistry. --- Immunoassay. --- Antigens --- Immunoglobulins --- Immunology --- Immunodiagnosis --- Biochemistry --- Immunity --- Biologic markers --- Biological markers --- Biomarkers --- Markers, Biochemical --- Indicators (Biology)

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This book describes the newest developments in antibody drug conjugates and immunotoxins, paving their way to clinical application. Lessons learned from the current state of the art are used to further improve our understanding of their mechanisms of action and off target activities. The book introduces scientists to all of the prerequisites that must be properly addressed, including identification of the right target, specific traits of target binding antibodies, proper selection of the toxic payload, internalization induced by binding, and next generation conjugation and linker technologies. These knowledge-based, revolutionary new drug principles will form the cornerstone of the future standard of care and will lead to major advances in application, as well as improved quality of life and patient survival rates. This book will be of interest to biotech companies and researchers working in the fields of immunology, pharmacology, and oncology.

Medicine. --- Cancer research. --- Antibodies. --- Pharmacology. --- Oncology. --- Pharmacotherapy. --- Biomedicine. --- Pharmacology/Toxicology. --- Cancer Research. --- Antibody-toxin conjugates. --- Conjugates, Antibody-toxin --- Immunoconjugates --- Immunoglobulin-toxin conjugates --- Immunotoxins --- Toxin-antibody conjugates --- Toxin-immunoglobulin conjugates --- Bioconjugates --- Immunopharmacology --- Immunotoxicology --- Toxins --- Toxicology. --- Monoclonal antibodies. --- Oncology  . --- Tumors --- Antibodies, Monoclonal --- Monoclonal immunoglobulins --- Immunoglobulins --- Molecular cloning --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Toxicology --- Cancer research --- Drug therapy --- Pharmacotherapy --- Therapeutics --- Drugs --- Antibodies --- Immune globulins --- Immune serum globulin --- Blood proteins --- Globulins --- Plasma cells --- Antibody diversity --- Antigens --- Bacterial immunoglobulin-binding proteins --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Pharmacy --- Physiological effect

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Janeway's Immunobiology is a textbook for students studying immunology at the undergraduate, graduate, and medical school levels. As an introductory text, students will appreciate the book's clear writing and informative illustrations, while advanced students and working immunologists will value its comprehensive scope and depth. Janeway's Immunobiology presents immunology from a consistent point of view throughout-that of the host's interaction with an environment full of microbes and pathogens. The Ninth Edition has been thoroughly revised bringing the content up-to-date with significant developments in the field, especially on the topic of innate immunity, and improving the presentation of topics across chapters for better continuity.

Immune System --- Immunity. --- Immunotherapy. --- Immunology. --- Immunologie --- physiology. --- physiopathology. --- Immunology --- Immunity --- Allergy and Immunology --- Immune System Diseases --- 577.27 --- Immunotherapies --- Immunity, Active --- Immunologic Techniques --- Disease --- Immunoglobulins --- Molecular bases of immunity. Molecular immunology --- immunology --- 577.27 Molecular bases of immunity. Molecular immunology --- Immunotherapy --- Immunobiology --- Life sciences --- Serology --- physiology --- physiopathology --- Immune Process --- Immune Response --- Immune Processes --- Immune Responses --- Process, Immune --- Response, Immune --- Molecular immunology --- Combined Antibody Therapeutics

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This volume focuses on IgG4-related disease (IgG4-RD), a novel clinical entity involving multiple organs and of unknown origin, associated with the abundant infiltration of IgG4-positive cells. It consists of nine chapters written by prominent experts in the field and discusses the disease concept, diagnosis and treatment, as well as recent findings on its pathogenesis and pathophysiology. As such, it offers an invaluable source of information for researchers and clinicians alike.

Immunoglobulin G. --- IgG --- Autoimmunologic diseases --- Medicine. --- Immunology. --- Rheumatology. --- Biomedicine. --- Internal medicine --- Connective tissues --- Joints --- Immunobiology --- Life sciences --- Serology --- Clinical sciences --- Medical profession --- Human biology --- Medical sciences --- Pathology --- Physicians --- Diseases --- Autoimmune diseases. --- Kidneys --- Diseases. --- Immunoglobulins --- Autoimmunity --- Immunologic diseases --- Kidney diseases --- Nephritis --- Nephropathy --- Renal diseases --- Immunoglobulin G --- Autoimmune Diseases. --- Pancreatitis. --- immunology. --- Pancreatitides --- Autoimmune Disease --- Disease, Autoimmune --- Diseases, Autoimmune --- Autoantibodies --- Self Tolerance

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Allergy and Immunology --- Hypersensitivity --- Immunity --- Disease --- Allergic Reaction --- Allergy --- Allergic Reactions --- Allergies --- Hypersensitivities --- Reaction, Allergic --- Reactions, Allergic --- Allergy Specialty --- Allergy, Immunology --- Immunology and Allergy --- Immunology, Allergy --- Immunology --- Specialty, Allergy --- immunology --- allergic diseases --- clinical immunology --- immunology diseases --- Immunoglobulins --- Allergy and Immunology. --- Hypersensitivity. --- Immunity. --- Immunology. --- Allergy. --- Allergic diseases --- Hypersensitivity, Immediate --- Immediate allergy --- Immediate hypersensitivity --- Immunologic diseases --- Immunoglobulin E --- Immunobiology --- Life sciences --- Serology --- Clinical Immunology --- Immune Process --- Immune Response --- Immune Processes --- Immune Responses --- Process, Immune --- Response, Immune