Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book provides a unified account of behavior change theories and broad coverage of application domains and best practices. From a psychological and human-computer interaction perspective, the book puts a strong emphasis on the psychological foundations of behavior change, and explores the relationship between technology and behavior change.

Health behavior --- Behavior modification. --- Research.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book offers a broad overview of the concepts and research findings in immunometabolism. The immune system is made up of numerous different cell types, pathways, and components that must be able to respond rapidly to a pathogen or cancer, but must also remain quiescent in the absence of challenges. Immune cells rely on metabolic pathways to adapt to changing environments and stimuli. Additionally, these cells can be modified in function or fate by fluctuations in available nutrients. The chapters in this book describe ways in which immune cells utilize and are regulated by metabolic pathways. Topics include how immune-cell metabolism shapes immune homeostasis, and how dysregulation of these pathways can lead to immune disorders. In different contexts, such as a tumor microenvironment, immune-cell function and identity may be modified not only by cytokines and checkpoint molecules, but also by nutrient availability and other metabolic stimuli. Transcriptional reprogramming confers many of the changes in immune cell metabolism that are seen when a T-cell, for example, undergoes activation or functional adaptation to different environments. Lastly, immune cells can destructively or protectively participate in human metabolic homeostasis or disorders. This book summarizes immune-metabolism from a variety of different perspectives, including the ways in which metabolic cues, pathways, and requirements of immune cells change in conditions of homeostasis and activation. The exploration of the significance of metabolic checkpoints and other cues, particularly in the context of cancer and immune disorders, may form the foundation for the development of therapeutics.

Immune system. --- Cancer. --- Medicine. --- Cancer research. --- Immunology. --- Medical microbiology. --- Posttranslational modification. --- Biomedicine. --- Posttranslational Modification. --- Medical Microbiology. --- Cancer Research. --- Co-translational modification --- Cotranslational modification --- Modification, Post-translational --- Post-translation protein modification --- Post-translational protein modification --- Posttranslation protein modification --- Posttranslational modification --- Posttranslational protein modification --- Genetic translation --- Proteins --- Immunobiology --- Life sciences --- Serology --- Cancer research --- Clinical sciences --- Medical profession --- Human biology --- Medical sciences --- Pathology --- Physicians --- Synthesis --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Tumors --- Immunological system --- Anatomy --- Immunology --- Post-translational modification . --- Microbiology. --- Oncology. --- Microbial biology --- Biology --- Microorganisms

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Weather control. Juxtaposing those two words is enough to raise eyebrows in a world where even the best weather models still fail to nail every forecast, and when the effects of climate change on sea level height, seasonal averages of weather phenomena, and biological behavior are being watched with interest by all, regardless of political or scientific persuasion. But between the late nineteenth century-when the United States first funded an attempt to "shock" rain out of clouds-and the late 1940s, rainmaking (as it had been known) became weather control. And then things got out of control. In Make It Rain, Kristine C. Harper tells the long and somewhat ludicrous history of state-funded attempts to manage, manipulate, and deploy the weather in America. Harper shows that governments from the federal to the local became helplessly captivated by the idea that weather control could promote agriculture, health, industrial output, and economic growth at home, or even be used as a military weapon and diplomatic tool abroad. Clear fog for landing aircraft? There's a project for that. Gentle rain for strawberries? Let's do it! Enhanced snowpacks for hydroelectric utilities? Check. The heyday of these weather control programs came during the Cold War, as the atmosphere came to be seen as something to be defended, weaponized, and manipulated. Yet Harper demonstrates that today there are clear implications for our attempts to solve the problems of climate change.

Weather control --- Science and state --- History. --- Cold War. --- control of nature. --- state funding. --- the state. --- water. --- weather control. --- Artificial weather control --- Cloud modification --- Weather modification --- Meteorology --- Hurricane modification

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Maximizing student capacity and restoring motivation-the key to school success Brain research has the power to revolutionize education, but it can be difficult for educators to implement innovative strategies without the proper knowledge or resources. The Education Revolution bridges the gap between neuroscience, psychology, and educational practice. It delivers what educators need: concrete applications of the most current and relevant research that they can use in their classrooms and schools. Readers will find • Teaching strategies based on the latest brain research, designed to advance academic performance • Scientifically sound, solution-focused practices to address the root of negative behaviors • Approaches to counteract the negative impact of technology on the brain • Concrete methods to improve school climate • Model lessons for teachers that demonstrate how to implement the given strategies Written by Horacio Sanchez, a leading authority on child and adolescent behavior and resiliency, this book shows educators how they can use our growing understanding of brain science to restore students' desire to learn; improve achievement, behavior and school climate; and revolutionize education. "Sanchez combines expertise in education, psychology, and neuroscience with extensive teaching experience and extraordinary insight into what makes us all behave the way we do." Dr. David L. Katz, President, American College of Lifestyle Medicine Director, Yale University Prevention Research Center "The Education Revolution focuses on the whole child through both academic and social aspects of learning. I feel confident that I can trust this research and use these ideas in my teaching." Kendra Hanzlik, Instructional Coach Prairie Hill Elementary School, College Community School District.

Cognitive learning. --- Cognitive neuroscience. --- Behavior modification. --- School environment.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This is the second edition of a very well received book that details how the sumoylation system functions and how it modulates numerous cellular activities. SUMO is a post-translational modifier in the ubiquitin super-family that has gained recognition over the last twenty years as an essential and prevalent regulatory molecule. Individual chapters explore the biochemistry, molecular biology, and cell biology of the sumoylation system and its substrate proteins. The book is divided into three themed parts: Molecular Functions (I), Cell Growth Regulation (II), and Diseases (III). Parts I and II focus on the contribution of sumoylation to cellular activities in both the nuclear and cytoplasmic compartments. The nuclear activities covered include nucleic acid metabolism (both RNA and DNA), chromosome structure and replication, and nucleocytoplasmic transport. Cytoplasmic processes presented include regulation of membrane ion channels, general metabolism, and apoptotic signalling. Topics in Part III include the role of sumoylation in developmental abnormalities (craniofacial and cardiovascular), diabetes, neurodegenerative diseases, cancer, and infections with viruses and bacteria. Each of the corresponding chapter authors is an active researcher who has made significant contributions to understanding sumoylation. This second edition provides updates and revisions to most of the original chapters plus adds six new chapters to address important developing areas of sumoylation research. This volume is intended for a scientific audience from undergraduates to independent researchers. The content will serve as both a solid introduction for the novice reader and an in depth treatment for the advanced scholar.

Posttranslational modification. --- Cell biology. --- Posttranslational Modification. --- Protein biosynthesis --- Protein synthesis --- Medicine. --- Proteins. --- Biomedicine. --- Biomedicine general. --- Protein Science. --- Cell Biology. --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Co-translational modification --- Cotranslational modification --- Modification, Post-translational --- Post-translation protein modification --- Post-translational protein modification --- Posttranslation protein modification --- Posttranslational modification --- Posttranslational protein modification --- Genetic translation --- Proteins --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Synthesis --- Synthesis. --- Metabolism --- Biochemistry. --- Cytology. --- Post-translational modification . --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Composition --- Health Workforce --- Proteins . --- Biomedicine, general.