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The book addresses new achievements in AFM instruments – e.g. higher speed and higher resolution – and how AFM is being combined with other new methods like NSOM, STED, STORM, PALM, and Raman. This book explores the latest advances in atomic force microscopy and related techniques in molecular and cell biology. Atomic force microscopy (AFM) can be used to detect the superstructures of the cell membrane, cell morphology, cell skeletons and their mechanical properties. Opening up new fields of in-situ dynamic study for living cells, enzymatic reactions, fibril growth and biomedical research, these combined techniques will yield valuable new insights into molecule and cell biology. This book offers a valuable resource for students and researchers in the fields of biochemistry, cell research and chemistry etc.
Atomic force microscopy. --- AFM (Microscopy) --- Scanning probe microscopy --- Biochemistry. --- Biomedical engineering. --- Biochemistry, general. --- Biomedical Engineering/Biotechnology. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Medicine --- Composition
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This book presents methodological and application research in detecting cellular and molecular biophysical properties based on atomic force microscopy (AFM) nanorobotics. Series methods for in situ label-free visualizing and quantifying the multiple physical properties of single cells and single molecules were developed, including immobilization strategies for observing fine structures of living cells, measurements of single-cell mechanics, force recognition of molecular interactions, and mapping protein organizations on cell surface. The biomedical applications of these methods in clinical lymphoma treatments were explored in detail, including primary sample preparation, cancer cell recognition, AFM detection and data analysis. Future directions about the biomedical applications of AFM are also given.
Physics. --- Immunology. --- Microscopy. --- Nanoscale science. --- Nanoscience. --- Nanostructures. --- Spectroscopy. --- Robotics. --- Automation. --- Nanoscale Science and Technology. --- Robotics and Automation. --- Biological and Medical Physics, Biophysics. --- Biological Microscopy. --- Spectroscopy and Microscopy. --- Atomic force microscopy. --- Robotics in medicine. --- Medicine --- AFM (Microscopy) --- Scanning probe microscopy --- Immunobiology --- Life sciences --- Serology --- Analysis, Microscopic --- Light microscopy --- Micrographic analysis --- Microscope and microscopy --- Microscopic analysis --- Optical microscopy --- Optics --- Biophysics. --- Biological physics. --- Analysis, Spectrum --- Spectra --- Spectrochemical analysis --- Spectrochemistry --- Spectrometry --- Spectroscopy --- Chemistry, Analytic --- Interferometry --- Radiation --- Wave-motion, Theory of --- Absorption spectra --- Light --- Spectroscope --- Biological physics --- Biology --- Medical sciences --- Physics --- Automatic factories --- Automatic production --- Computer control --- Engineering cybernetics --- Factories --- Industrial engineering --- Mechanization --- Assembly-line methods --- Automatic control --- Automatic machinery --- CAD/CAM systems --- Robotics --- Automation --- Machine theory --- Nanoscience --- Nano science --- Nanoscale science --- Nanosciences --- Science --- Qualitative --- Analytical chemistry
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