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Membrane proteins are essential for the diverse biological functions of the cells and intercellular communication in living organisms. With the recent developments in the methodologies, the research on membrane proteins has been undergoing a major transformation. In this informative book, the biological and dynamic behaviour of membrane proteins are introduced, discussed, and reviewed by some of the leading researchers in the field. The main objective of this compendium is to present the recent research in the fundamental and advanced concepts and methodologies used for studying membrane proteins. Membrane protein purification and reconstitution, protein-lipid interaction, ion/substrate transport, conformational and functional dynamics, the interaction of infectious agents, cell death, and organelle morphology are among the topics that are covered. This reprint is intended for a broad range of novice and experienced scientists with different levels of experience, from biophysicists and biochemists to microbiologists, cell biologists, and physiologists.

Membrane proteins. --- Membranes (Biology) --- Proteins

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This book covers the molecular structures and the cellular and in vivo function of endosomes and lysosomes, i.e. intracellular vesicles which are involved in many cellular processes such as endocytosis, intracellular trafficking, degradation of material from inside (e.g. autophagy) and outside the cell as well as exocytosis. Membranes of endolysosomal organelles contain an amazing number and diversity of ion channels. These ion channels are the topic of the present book that focusses on describing the structure, the biophysical properties, physiological functions of endolysosomal ion channels at the molecular, cellular and in vivo level. .

Pharmacology. --- Physiology. --- Cytology. --- Life sciences. --- Cell Biology. --- Life Sciences. --- Biosciences --- Sciences, Life --- Science --- Cell biology --- Cellular biology --- Biology --- Cells --- Animal physiology --- Animals --- Anatomy --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Physiology --- Physiological effect --- Endosomes. --- Ion channels. --- Lysosomes. --- Cell organelles --- Channels, Ion --- Biological transport, Active --- Ion-permeable membranes --- Membrane proteins --- Receptosomes

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Ions, their transport across membranes, and their flow through specialized ion channels are central to the understanding of brain function - normal and pathological. This text explores them fully for medical practitioners in the neurosciences.

Brain --- Epilepsy --- Cerebrovascular disease --- Ion channels. --- Neurochemistry. --- Neural transmission. --- Nerve transmission --- Nervous transmission --- Neurotransmission --- Synaptic transmission --- Transmission of nerve impulses --- Neural circuitry --- Neurophysiology --- Neurotransmitters --- Biochemistry --- Neurosciences --- Channels, Ion --- Biological transport, Active --- Ion-permeable membranes --- Membrane proteins --- Apoplexy --- Cerebral circulation disorders --- Cerebral vascular accident --- Cerebrovascular accident --- Cerebrovascular disorders --- Cerebrovascular syndrome --- CVA (Disease) --- Stroke --- Neglect (Neurology) --- Developmental disabilities --- Convulsions --- Spasms --- Cerebrum --- Mind --- Central nervous system --- Head --- Pathophysiology. --- Blood-vessels --- Diseases --- Brain Diseases --- Ions --- Neurotransmission. --- physiopathology. --- metabolism.