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This book, now published in its second edition, covers a wide range of topics relating to the use of radiopharmaceuticals. The basics of nuclear chemistry, radiochemistry, and radiopharmacology are considered in detail, regulatory issues are reviewed, and potential applications in drug development, translational medicine, clinical diagnostics, and targeted therapy are discussed. Compared with the first edition, the chapters on targeted therapy with alpha- and beta-emitting radiopharmaceuticals and theranostics are completely new. Other chapters have been updated and revised as necessary. Radioisotope-based molecular imaging probes (radiopharmaceuticals) provide unprecedented insights into biochemistry and function in both normal and diseased states of living systems, with unbiased in vivo measurements of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology, including functional magnetic resonance imaging, can provide such high sensitivity and specificity at a tracer level. This book, written by an experienced radiochemist and scientist, offers valuable insights into the full range of applications of this technology.

Nuclear medicine. --- Oncology. --- Neurology. --- Nuclear Medicine. --- Medicine --- Nervous system --- Neuropsychiatry --- Tumors --- Atomic medicine --- Radioisotopes in medicine --- Medical radiology --- Radioactive tracers --- Radioactivity --- Diseases --- Physiological effect --- Diagnostic imaging. --- Molecular diagnosis. --- Radiopharmaceuticals. --- Tomography, Emission. --- Computerized emission tomography --- Emission tomography --- PET (Tomography) --- PET-CT (Tomography) --- Positron emission tomography --- Positron emission transaxial tomography --- Radionuclide tomography --- Scintigraphy, Tomographic --- Tomography, Radionuclide --- Diagnosis --- Diagnostic imaging --- Positrons --- Radioisotope scanning --- Radiopharmaceutical agents --- Pharmacology --- Molecular diagnostics --- Molecular biology --- Clinical imaging --- Imaging, Diagnostic --- Medical diagnostic imaging --- Medical imaging --- Noninvasive medical imaging --- Diagnosis, Noninvasive --- Imaging systems in medicine --- Data processing --- Emission --- Molecular aspects --- Molecular Imaging. --- Radiotherapy. --- Radionuclide Imaging. --- Positron-Emission Tomography. --- PET Imaging --- PET Scan --- Positron-Emission Tomography Imaging --- Tomography, Positron-Emission --- Imaging, PET --- Imaging, Positron-Emission Tomography --- PET Imagings --- PET Scans --- Positron Emission Tomography --- Positron Emission Tomography Imaging --- Positron-Emission Tomography Imagings --- Scan, PET --- Tomography Imaging, Positron-Emission --- Tomography, Positron Emission --- Gamma Camera Imaging --- Radioisotope Scanning --- Scanning, Radioisotope --- Scintigraphy --- Scintiphotography --- Imaging, Gamma Camera --- Imaging, Radionuclide --- Radiation Therapy --- Radiation Therapy, Targeted --- Radiation Treatment --- Targeted Radiation Therapy --- Radiotherapy, Targeted --- Targeted Radiotherapy --- Radiation Therapies --- Radiation Therapies, Targeted --- Radiation Treatments --- Radiotherapies --- Radiotherapies, Targeted --- Targeted Radiation Therapies --- Targeted Radiotherapies --- Therapies, Radiation --- Therapies, Targeted Radiation --- Therapy, Radiation --- Therapy, Targeted Radiation --- Treatment, Radiation --- Disease --- Radiation --- Imaging, Molecular --- Radiopharmaceutical --- radiotherapy --- therapeutic use

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This is the third, completely updated edition of a comprehensive book in which many of the world’s leading lung cancer specialists discuss the recent advances in the radiation oncology of lung cancer and reflect on the latest research findings in lung cancer and other intrathoracic malignancies. Lung cancer remains the major cancer killer in both sexes worldwide. It is so despite significant progress in recent decades in both diagnostic and treatment approaches. New biological and technological advances in this field are now faster incorporated in the overall decision-making process and are bringing fast and substantial improvements in both survivals and quality of life of lung cancer patients. Optimized patient-oriented approaches are reality of the third decade of this millennium and thoracic oncologists strive towards nothing but seamlessly delivering it in a continuous battle with lung cancer. The first three sections of the work cover the basic science of lung cancer, clinical investigations, including histology and staging, and a wide range of fundamental treatment considerations. Current treatment strategies for small cell and non-small cell lung cancer as well as other intrathoracic malignancies are then explained and evaluated in detail, with due attention to novel approaches that promise further improvements in outcome. The various types of treatment-related toxicity are discussed, and quality of life studies and prognostic factors are also considered. After evaluating the latest technological and biological advances, including stereotactic radiotherapy, and particle therapy, the book concludes by thorough consideration of specific aspects of clinical research in lung cancer. This concise yet comprehensive book is an invaluable resource for radiation oncologists.

Lung Neoplasms. --- Radiation Oncology. --- Radiotherapy. --- Diagnostic Imaging. --- Proton Therapy. --- Positron Emission Tomography Computed Tomography. --- CT PET --- CT PET Scan --- PET CT Scan --- PET-CT --- PET-CT Scan --- Positron Emission Tomography-Computed Tomography --- CT PET Scans --- CT Scan, PET --- CT Scans, PET --- PET CT Scans --- PET Scan, CT --- PET Scans, CT --- PET-CT Scans --- Scan, CT PET --- Scan, PET CT --- Scan, PET-CT --- Scans, CT PET --- Scans, PET CT --- Scans, PET-CT --- Proton Beam Radiation Therapy --- Proton Beam Therapy --- Proton Beam Therapies --- Proton Therapies --- Therapies, Proton --- Therapies, Proton Beam --- Therapy, Proton --- Therapy, Proton Beam --- Protons --- Imaging, Diagnostic --- Imaging, Medical --- Medical Imaging --- Radiologic and Imaging Nursing --- Image Processing, Computer-Assisted --- Radiation Therapy --- Radiation Therapy, Targeted --- Radiation Treatment --- Targeted Radiation Therapy --- Radiotherapy, Targeted --- Targeted Radiotherapy --- Radiation Therapies --- Radiation Therapies, Targeted --- Radiation Treatments --- Radiotherapies --- Radiotherapies, Targeted --- Targeted Radiation Therapies --- Targeted Radiotherapies --- Therapies, Radiation --- Therapies, Targeted Radiation --- Therapy, Radiation --- Therapy, Targeted Radiation --- Treatment, Radiation --- Disease --- Radiation --- Oncology, Radiation --- Radiology, Therapeutic --- Therapeutic Radiology --- Cancer of the Lung --- Neoplasms, Lung --- Neoplasms, Pulmonary --- Cancer of Lung --- Lung Cancer --- Pulmonary Cancer --- Pulmonary Neoplasms --- Cancer, Lung --- Cancer, Pulmonary --- Cancers, Lung --- Cancers, Pulmonary --- Lung Cancers --- Lung Neoplasm --- Neoplasm, Lung --- Neoplasm, Pulmonary --- Pulmonary Cancers --- Pulmonary Neoplasm --- therapeutic use --- radiotherapy --- Lungs --- Cancer --- Medical radiology. --- Oncology. --- Radiology. --- Respiratory organs --- Pneumology. --- Diseases. --- Respiratory diseases --- Radiological physics --- Physics --- Tumors --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics