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Litt’s Drug Eruption & Reaction Manual is a succinct reference to give clinicians the essential information for an informed decision about patient management. The full database from which it is derived ― Litt’s Drug Eruption & Reaction database: www.drugeruptiondata.com ― currently holds over 1800 drug profiles with over 73,000 documented drug reactions, as evidenced by well over 156,000 references on PubMed, and is internationally relied upon by medical practitioners for its unparalleled focus on adverse effects and cutaneous reactions. This edition provides documentation of adverse reactions to the 1500 most consulted drug and herbal profiles Gives clinicians managing patients with many different medications a route to making an informed decision about problematic reactions, offers clinicians a one-stop reference for the essential information about a drug; Contents : A to Z listing of the 1500 most consulted drug and herbal profiles (including supplements, vaccines, and botanicals), including generic name and trade names; pharmaceutical company; indications; half-life; and pregnancy category descriptions of important reactions, list of drugs that cause important adverse reactions list of main classes of drugs, 28 tables showing reactions of members of a class of drugs (such as statins or monoclonal antibodies), enabling clinicians to see at a glance whether a reaction is common to all drugs included in that class, or to a majority of them, or is known in only a handful―information that is critical for an informed decision to change drugs within the same class, 2 tables showing reported genetic associations with cutaneous adverse drug reactions and recommendations regarding genetic screening to prevent cutaneous adverse drug reactions, a concordance of synonyms and trade names for ease of cross-reference.

Drug Eruptions. --- Drug Interactions. --- Skin Manifestations. --- Allergie aux médicaments. --- Interactions médicamenteuses. --- Dermatoses. --- Toxidermies.

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In this thesis, the author proposes "metal-responsive base pair switching" of ligand-modified nucleobases as a novel tool for stimuli-responsive control of DNA assemblies. It is written to demonstrate broad applicability of the base pair switching in dynamic DNA nanotechnology and inspire researchers to use this technique. Based on specific interactions between ligand-type nucleobases and target metal ions, in this volume, DNA hybridization was dynamically controlled through strand displacement reactions. The base pair switching was further applied to develop metal-dependent DNA molecular machines. This novel strategy for stimuli-responsive regulation of DNA assemblies will greatly expand the scope of dynamic DNA nanotechnology. This volume uniquely features importance of elaborate molecular design based on chemistry for imparting stimuli responsiveness to DNA assemblies.

Biomaterials. --- Nucleic acids. --- Coordination compounds. --- Nanotechnology. --- Self-assembly (Chemistry). --- Biocompatible Materials. --- Nucleic Acids. --- Layer-by-Layer Nanoparticles --- Nucleic Acid. --- Coordination Chemistry. --- Self-assembly. --- DNA-ligand interactions.