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This book on current approaches to the use of drugs in dentistry, now in an extensively revised second edition, aims to equip practitioners with a sound understanding of both the scientific evidence for various interventions and the comparative efficacy of those interventions. The focus is on the drugs most commonly used in conjunction with dental treatment, including local anesthetics, analgesics, antibiotics, sedatives, and drugs for the management of medical emergencies. Summaries of the scientific evidence from the available published literature are provided, with assessment of the level and quality of the evidence base. A unique aspect of the book is its focus on current, evidence-based recommendations from professional organizations with regard to special topics, such as antibiotic prophylaxis, pediatric considerations, and management of medically compromised patients. Emphasis is placed on evidence from randomized controlled trials, systematic reviews and meta-analyses, and in order to further enhance the up-to-date nature of the book, each chapter includes guidance on online resources, such as useful non-commercial websites.
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"Continually revised and updated for 50 years, Applied Therapeutics: The Clinical Use of Drugs is the gold standard for patient centered drug therapeutics. With its acclaimed case-based approach, it promotes mastery and application of the fundamentals of drug therapeutics. Featuring contributions from more than 200 experienced clinicians, every chapter reflects our ever-changing knowledge of drugs and the application of this knowledge to the individualized therapy of patients. As students progress from the General Principles section to chapters on specific diseases, they will benefit from practical problem-solving techniques that help devise effective evidence-based drug treatment plans"--
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This book aims to compile the latest scientific information on hand, foot, and mouth disease (HFMD), including its epidemiology, etiology, pathology, immune response and vaccine development. Interestingly, the authors shared their own research experience and offered distinctive insights into the pathogenesis of HFMD and vaccine development. The intended audience, including university researchers, graduate students, and vaccine engineers, is well defined. The book is positioned as a resource that not only presents current knowledge but also has the potential to inspire further research in understanding immune pathogenesis and advancing vaccine development for HFMD.
Virology. --- Immunology. --- Pharmacology. --- Epidemiology.
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This book is built around ion channel research and, more specifically, ion channels as important therapeutic drug targets. Under the editorial leadership of Gary Stephens in academic research and Edward Stevens from industry, the aim is to bring these strands together to provide a cutting-edge translational reference on ion channel drug discovery. Exploiting our knowledge of ion channel structure and function has clear current and future potential to intervene and correct the pathophysiology associated with debilitating conditions, including cardiovascular disease, diabetes, cystic fibrosis, pain, epilepsy, and neurodegenerative disorders. Individual chapters have a disease focus, also providing a “case study story” that will also appeal to a clinical audience, while background information on a given ion channel is presented to provide a solid reference for undergraduate and postgraduate teaching.
Neurosciences. --- Neurochemistry. --- Pharmacology. --- Neuroscience.
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