ID - 131906539 TI - Neuroimmune Interactions in Pain AU - Ji, Ru-Rong AU - Cheng, Jianguo AU - Ji, Jasmine AU - SpringerLink (Online service) PY - 2023 SN - 9783031292316 9783031292309 9783031292323 9783031292330 PB - Cham Springer International Publishing :Imprint: Springer DB - UniCat KW - Anesthesiology KW - Pharmacology. Therapy KW - Neuropathology KW - neurologie KW - hersenen KW - anesthesie KW - analgesie KW - pijn KW - Chronic pain KW - Neuroimmunology. KW - Immunological aspects. KW - Treatment. UR - https://www.unicat.be/uniCat?func=search&query=sysid:131906539 AB - As lifespans increase, more people around the world find themselves victims of chronic pain. In spite of this, treatment options continue to be severely limited. Anti-inflammatory drugs can only do so much, while painkillers like opioids have led to crippling addictions and fatal overdoses. The subject of the book is the role of immune cells, including glial cells, and neuroimmune interactions in chronic pain. The book begins by examining the preclinical and clinical evidence supporting the involvement of non-neuronal cells in chronic pain. It discusses the interactions between non-neuronal cells and neurons in the regulation of chronic pain. It then presents the implications of these findings, including promising and emerging treatments such as specialized pro-resolving mediators (SPMs, such as resolvins and protectins), immune cell therapy, and complementary and alternative medicine, as well as neuromodulation and regenerative medicine, which may prove to be the turning point for hundreds of millions of patients world-wide who struggle to escape from the shadow of chronic pain. The book presents ground-breaking research that will alter current perspectives on chronic pain. ER -