TY - BOOK ID - 135558018 TI - New Perspective in Atrial Fibrillation PY - 2021 PB - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute DB - UniCat KW - postoperative atrial fibrillation KW - biomarkers KW - coronary artery bypass grafting KW - miRNA KW - circRNA KW - mtDNA KW - SNPs KW - atrial fibrillation KW - acute myocardial infarction KW - heart rate variability KW - autonomic nervous system KW - bleeding risk KW - age KW - left atrial appendage closure KW - coronary artery disease KW - prognosis KW - anticoagulation KW - antiplatelet therapy KW - hypertension KW - elderly KW - prevention KW - ganglionated plexi KW - ablation KW - dementia KW - early-onset KW - n/a KW - ischemic stroke KW - risk factor KW - new oral anticoagulants KW - mitochondria KW - cardiac remodeling KW - pharmacotherapy KW - electroporation KW - pulsed field ablation KW - cardiac KW - heart KW - arrhythmia KW - NOAC KW - VKA KW - statin KW - outcome KW - mortality KW - paroxysmal atrial fibrillation KW - catheter ablation KW - epicardial adipose tissue KW - persistent atrial fibrillation KW - posterior wall KW - hybrid ablation KW - convergent ablation KW - atrial tachycardia KW - mechanism KW - spatiotemporal dispersion KW - left atrial appendage occlusion KW - BNP KW - atrial remodeling KW - atrial cardiopathy KW - cardiac ablation KW - irreversible electroporation UR - https://www.unicat.be/uniCat?func=search&query=sysid:135558018 AB - In spite of the large volume of associated research, the pathophysiological mechanisms involved in atrial fibrillation (AF) onset and recurrence remain uncertain. This may explain why the performances of thromboembolic and bleeding prediction scores in AF patients are limited. In the past few years, the concept of atrial cardiopathy has emerged as a promising lead to connect AF to stroke, heart failure, and inflammatory processes: indeed, all of the mechanisms associated with atrial remodeling and the development of atrial cardiopathy are also likely to promote the development of AF. This recent concept of atrial cardiopathy suggests that the real trigger of stroke may be an abnormal atrial substrate rather than atrial rhythm itself. In this setting, AF could be seen as a symptom of atrial cardiopathy rather than a risk factor of stroke. In the absence of validated clinical markers of atrial cardiopathy, the search for the mechanism of AF remains the cornerstone of cardioembolic stroke prevention for now.The aim of this Special Issue is to gather basic research as well as pathophysiological and epidemiological papers focused on the relationship between atrial substrates and atrial fibrillation onset, recurrence, and outcomes. ER -