TY - BOOK ID - 139047152 TI - Male Germline Chromatin AU - Griffin, Darren AU - Ellis, Peter PY - 2020 PB - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute DB - UniCat KW - mouse sperm chromatin KW - chromosome organization KW - nuclear-3D-parameters KW - spermiogenesis KW - chromatin remodeling KW - DNA double-strand breaks KW - genetic instability KW - mutations KW - sperm DNA damage KW - DNA fragmentation KW - infertility KW - assisted reproduction KW - miscarriage KW - implantation KW - nuclear organization KW - sperm KW - morphometrics KW - chromosome painting KW - nucleoli KW - NOR KW - chromosome associations KW - meiotic prophase KW - spermatocytes KW - Mus m. domesticus KW - Robertsonian chromosomes KW - chromosome translocation KW - Y chromosome KW - testis KW - spermatogenesis KW - SLY KW - mouse KW - oxidative stress KW - reactive oxygen species KW - chromatin KW - DNA oxidation KW - male infertility KW - spermatozoa KW - chromosomes KW - chromosome territories KW - centromeres KW - male germ cells KW - telomeres KW - reproductive aging KW - nuclear organisation KW - epigenetic inheritance KW - histone retention KW - in vitro fertilisation UR - https://www.unicat.be/uniCat?func=search&query=sysid:139047152 AB - Spermatogenesis requires radical restructuring of germline chromatin at multiple stages, involving coordinated waves of DNA methylation/demethylation, histone modification, and the replacement and removal that occurs before, during, and after meiosis. This Special Issue will draw together papers that address all aspects of chromatin organization and dynamics in the male germ line, in humans, and in model organisms. In particular, we will invite authors to discuss novel methods for studying germline chromatin structure, the interplay between chromatin structure and susceptibility to DNA damage and mutation, chromatin modifications associated with epigenetic inheritance in the early embryo, and the impact this work has for understanding natural fertility and improving assisted reproduction techniques. ER -