TY - BOOK ID - 7689376 TI - Organotrifluoroborate preparation, coupling and hydrolysis PY - 2013 SN - 3319011332 3319011340 PB - Cham [Switzerland] : Springer, DB - UniCat KW - Chemistry KW - Physical Sciences & Mathematics KW - Biochemistry KW - Salts. KW - Hydrolysis. KW - Chemistry. KW - Organic chemistry. KW - Chemical engineering. KW - Catalysis. KW - Organic Chemistry. KW - Industrial Chemistry/Chemical Engineering. KW - Solvolysis KW - Salt deposits KW - Salinity KW - Chemistry, Organic. KW - Chemistry, Industrial KW - Engineering, Chemical KW - Industrial chemistry KW - Engineering KW - Chemistry, Technical KW - Metallurgy KW - Activation (Chemistry) KW - Chemistry, Physical and theoretical KW - Surface chemistry KW - Organic chemistry KW - Physical organic chemistry. UR - https://www.unicat.be/uniCat?func=search&query=sysid:7689376 AB - Alistair Lennox's thesis reports on the reactivity of organotrifluoroborates, which are becoming increasingly important reagents in synthesis. The thesis is divided into three sections. The first section describes a method for preparing organotrifluoroborates. The second section reports on a mechanistic investigation into the main application of RBF3K reagents as coupling partners in Suzuki-Miyaura coupling, phenomena identified as arising from organotrifluoroborate hydrolysis and fluoride release. The final section reports on a detailed investigation into the hydrolysis mechanism, a prerequisite for their Suzuki-Miyaura coupling, and how it may be predicted and controlled. This research has uncovered many interesting and useful details and shows how problems associated with Suzuki-Miyaura coupling can best be addressed. There has already been wide industrial uptake of the new procedures and insights. The broad nature and clear and succinct style will make the thesis a valuable resource for anyone working in synthesis, organometallic chemistry, or in homogeneous catalysis. ER -