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"Praise for the First Edition " . . . the book is a valuable addition to the literature in the field, serving as a much-needed guide for both clinicians and advanced students."--Zentralblatt MATH A new edition of the cutting-edge guide to diagnostic tests in medical research In recent years, a considerable amount of research has focused on evolving methods for designing and analyzing diagnostic accuracy studies. Statistical Methods in Diagnostic Medicine, Second Edition continues to provide a comprehensive approach to the topic, guiding readers through the necessary practices for understanding these studies and generalizing the results to patient populations. Following a basic introduction to measuring test accuracy and study design, the authors successfully define various measures of diagnostic accuracy, describe strategies for designing diagnostic accuracy studies, and present key statistical methods for estimating and comparing test accuracy. Topics new to the Second Edition include: Methods for tests designed to detect and locate lesions Recommendations for covariate-adjustment Methods for estimating and comparing predictive values and sample sSample size calculation for multiple reader studies when pilot data are available Updated meta-analysis methods, now incorporating random effectsThree case studies thoroughly showcase some of the questions and statistical issues that arise in diagnostic medicine, with all associated data provided in detailed appendices. A related web site features Fortran, SAS(r), and R software packages so that readers can conduct their own analyses. Statistical Methods in Diagnostic Medicine, Second Edition is an excellent supplement for biostatistics courses at the graduate level. It also serves as a valuable reference for clinicians and researchers working in the fields of medicine, epidemiology, and biostatistics"--Provided by publisher.

Mathematical statistics --- Diagnostic Techniques and Procedures --- Data Interpretation, Statistical. --- Diagnostic Techniques and Procedures. --- Data Interpretation, Statistical

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Diagnostic Techniques and Procedures. --- Diagnostic immunohistochemistry. --- Immunohistochemistry --- Neoplasms --- methods. --- diagnosis.

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Statistique médicale --- Analyse statistique --- Diagnostic techniques and procedures

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L'ECN est un concours difficile, éprouvant, exigeant un maximum d'efforts pendant l'épreuve, et surtout nécessitant de ne pas perdre de temps. Ces dernières années, chaque concours a vu son lot de dossiers déstabilisants, en particulier par les pathologies qui ont été traités : dossier de canal artériel persistant en 2010, de fièvre typhoïde en 2011, de neuroblastome en 2012, de Von-Hippel- Lindau et Amylose en 2013, etc. Ces dossiers étaient d'une part difficiles de par les pathologies complexes qu'ils abordaient, mais surtout pouvaient faire perdre du temps ou leurs moyens aux candidats, avec un possible retentissement sur la rédaction des autres dossiers. L'objectif de cet ouvrage est d'apporter un certain nombre de notions clés sur un ensemble de pathologies rares, sous formes de fiches de synthèse, afin d'y voir plus clair et de pouvoir les identifier plus rapidement.

Rare diseases - Handbooks --- Diagnostic Techniques and Procedures --- Syndrome

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Diagnosis, Laboratory --- Diagnostic Techniques and Procedures --- Clinical Laboratory Techniques