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This book provides information on the incidence of fungi and mycotoxins in some African countries, the health implications and possible intervention control strategies for mycotoxins in developing countries and in Africa in particular. It will therefore be of interest to students, educators, researchers and policy makers in the fields of medicine, agriculture, food science and technology, trade and economics. Food regulatory officers also have quite a lot to learn from the book. Although a lot of the generated data in the area of mycotoxicology are available to the developed world, information on the subject area from Africa is scanty and not usually available in a comprehensive form. This book attempts to address the gap. Being an open access book, it will be of great benefit to scientists in developing countries who have limited access to information due to lack of funds to pay or subscribe for high quality journals and data from commercial publishing and database companies.
Mycotoxins. --- Food --- Safety measures. --- Fungal toxins --- Fungal metabolites --- Microbial toxins --- Mycotoxicoses --- Toxigenic fungi --- Medical toxicology
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Mycotoxins. --- Microbiology. --- Microbial biology --- Biology --- Microorganisms --- Fungal toxins --- Fungal metabolites --- Microbial toxins --- Mycotoxicoses --- Toxigenic fungi
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Mycotoxins. --- Microbiology. --- Microbial biology --- Biology --- Microorganisms --- Fungal toxins --- Fungal metabolites --- Microbial toxins --- Mycotoxicoses --- Toxigenic fungi
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Mycotoxins are secondary metabolites produced by molds. Although the primary role of these toxins is thought to be related to the colonisation of the environment by the fungi--mycotoxins are able to kill other micro-organisms (antimicrobial effect) and/or plant cells (mycotoxin-producing fungi being necrophagic)--the exposure of animals and humans to mycotoxins through the consumption of mycotoxin-contaminated food and feeds leads to diseases and death. Among the different mycotoxins described (more than 350 mycotoxins have been identified), deoxynivalenol (DON or vomitoxin) produced by Fusarium species has attracted the most attention due to its prevalence and toxicity. DON is part of a family of mycotoxins called trichothecenes that are small sesquiterpenoids with an epoxide group at positions 12-13 allowing their binding to ribosomes causing the so-called ribosome stress response, characterized by the activation of various protein kinases that lead to alterations in gene expression and cellular toxicity in animals, humans and plants. Here, we compiled very recent findings regarding DON and its derivatives: i. their prevalence in human food; ii. the estimation of the exposure of humans to them using biological markers; iii. their roles during plant-fungi interaction; iv. the alteration caused by them in animals and humans, particularly at low doses that are close to those observed in farm animals and human consumers; v. possible strategies to decrease their presence in food and feeds. Overall, this book will give the reader a clear and global view on this important mycotoxin produced by Fusarium species which is responsible for huge economic loss and health issues. Dr. Marc Maresca Guest Editor.
Mycotoxins --- Mycotoxins. --- Fungal toxins --- Fungal metabolites --- Microbial toxins --- Mycotoxicoses --- Toxigenic fungi
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Mycotoxins. --- Mycotoxins --- Fungal toxins --- Fungal metabolites --- Microbial toxins --- Mycotoxicoses --- Toxigenic fungi --- Fungal Toxins --- Toxins, Fungal --- Mushroom Poisoning --- Mycotoxin
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This Edited Volume Mycotoxins - Impact and Management Strategies is a collection of reviewed and relevant research chapters, offering a comprehensive overview of recent developments in the field of Mycotoxicology. The book comprises of single chapters authored by various researchers and edited by an expert active in this research area. This book is divided into three sections. Section 1 consists of one chapter that gives an overview of the socioeconomic impact of mycotoxins. Section 2 has five chapters that address the prevention and control of aflatoxins both at pre- and post-harvest stages. Section 3 has two chapters that deal with health impact and control in the poultry industry. This publication aims at providing a thorough overview of the latest research efforts in the field and opens new possible research paths for further novel developments in addressing the problem of mycotoxins.
Mycotoxins. --- Fungal toxins --- Fungal metabolites --- Microbial toxins --- Mycotoxicoses --- Toxigenic fungi --- Toxicology --- Toxicology and Pharmaceutical Science --- Mycotoxicology --- Pharmacology --- Health Sciences
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This book is one of three volumes expanding upon content found in Mycotoxins in Foodstuffs, Second Edition, and focuses on milk and milk products, and meat. Foodstuffs of plant origin that play only a minor role in mycotoxin contamination, such as asparagus, are also covered. Mycotoxins in Animal Products - Milk and Milk Products, and Meat comprises: More than 100 new publications and 300 publications in all Single chapter overview with all mycotoxins and each foodstuff that is contaminated Coverage of "co-contamination," showing the co-occurrence of mycotoxins in a foodstuff, where possible Coverage of "further contamination,“ describing further foodstuffs with their mycotoxins documented, where possible List of articles dealing with conventionally and organically produced foodstuffs and their mycotoxin contamination .
Mycotoxins. --- Food --- Microbiology. --- Sanitary microbiology --- Fungal toxins --- Fungal metabolites --- Microbial toxins --- Mycotoxicoses --- Toxigenic fungi --- Bacteriology --- Food—Biotechnology. --- Food Science.
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Biotechnology --- Fungal metabolites. --- Microbial biotechnology. --- Fungi --- Biotechnology. --- Fungal biotechnology --- Microorganisms --- Industrial microbiology --- Biotechnological microorganisms --- Microbial metabolites --- Plant metabolites --- Physiology
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Mycotoxins are secondary metabolites produced by several fungal species. They can contaminate human food and animal feed, and have been a threat for thousands of years. The gastrointestinal tract is the first target when ingesting mycotoxin-contaminated food or feed. As unlikely as it sounds, the investigations concerning the effects of mycotoxins on the intestine are still in their early stages. This book gathers the most recent advances related to the characterization of the intestinal toxicity of mycotoxins. Substantial data assembled on the damage caused to a number of histological structures and functions of the intestine remove any remaining doubt about this organ being a primary target for the toxicity of mycotoxins. An interesting overview of the detrimental effects of mycotoxins on the gut-hosted microbiota-now regarded as a fully-fledged organ associated with the gut-is also given. Finally, outstanding contributions in this book address questions relating to the suitability of current regulations to protect against alterations of the intestine, and to the efficacy assessment of new detoxification strategies using the intestinal toxicity of mycotoxins as a relevant endpoint.
Mycotoxins. --- Intestines --- Diseases. --- Bowel diseases --- Enteropathy --- Intestinal diseases --- Fungal toxins --- Fungal metabolites --- Microbial toxins --- Mycotoxicoses --- Toxigenic fungi
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Pathogenic fungi and mycotoxins threaten plant and animal health and cause economic losses. This book focuses on the recent research progress into pathogenic fungi and mycotoxins in China. The molecular mechanisms of mycotoxin biosynthesis and pathogenic fungi growth and development are reported from the perspectives of transcription regulation, histone modification and enzymes, providing a theoretical basis for discovering new control targets. This Special Issue not only includes a review about the microbial degradation of mycotoxins, but also discusses several new chemical and biological methods which inhibit the biosynthesis of mycotoxin. Special attention is also given to the effect of nutrition on the production of mycotoxins. Some papers have also been collected about detection assays and the risk assessments of mycotoxins. The fundamental and applied research into mycotoxins is not only of particular interest but is also important for reducing economic losses.
Pathogenic fungi. --- Mycotoxins. --- Fungal toxins --- Fungal metabolites --- Microbial toxins --- Mycotoxicoses --- Toxigenic fungi --- Fungi, Pathogenic --- Fungi --- Pathogenic microorganisms --- Medical mycology