Choose an application
Choose an application
Choose an application
Choose an application
Choose an application
Choose an application
Choose an application
Life is all around us, abundant and diverse, it is extraordinary. But what does it actually mean to be alive? Nobel prize-winner Paul Nurse has spent his career revealing how living cells work. In this book, he takes up the challenge of defining life in a way that every reader can understand. It is a shared journey of discovery; step by step he illuminates five great ideas that underpin biology. He traces the roots of his own curiosity and knowledge to reveal how science works, both now and in the past. Using his personal experiences, in and out of the lab, he shares with us the challenges, the lucky breaks, and the thrilling eureka moments of discovery. To survive the challenges that face the human race today - from climate change, to pandemics, loss of biodiversity and food security - it is vital that we all understand what life is.
Choose an application
Choose an application
Cystic Fibrosis is an inherited disease that starts in utero. It is caused by a defective protein called the CF transmembrane conductance regulator (CFTR) and while the effects are seen throughout the body, changes in the lungs, gastrointestinal tract, pancreas and liver primarily impact nutritional status. Survival and pulmonary function have been linked to nutritional status. Malnutrition and growth failure were historically the hallmark of disease. Patients with pancreatic insufficiency require pancreatic enzyme replacement therapy and fat-soluble vitamin supplements. With improvements in many areas including newborn screening, nutrition supplements, pancreatic enzymes, CFTR modulator drugs, inhaled antibiotics and mucolytics, life expectancy has increased. In this issue, we will review the latest information in children and adults regarding important factors that play a role in optimizing nutrition status, including body composition, the gut microbiome, food security, pancreatic enzyme replacement therapy, growth and bone health, and micronutrient abnormalities. Pediatric and adult providers both need to be aware of the nuances of care as more patients with CF become adults. Optimizing nutritional status, anticipating and preventing the complications of CF will result in best management practice.
Choose an application
Comment concevoir la vie dans sa double dimension du vivant et du vécu, de la matière et de l'expérience ? À cette question, la philosophie et, plus récemment, les sciences sociales, ont apporté toutes sortes de réponses, privilégiant souvent l'une ou l'autre de ces dimensions - le biologique ou le biographique. Est-il toutefois possible de les penser ensemble et de réconcilier ainsi les approches naturaliste et humaniste ? S'appuyant sur une série de recherches conduites sur trois continents, Didier Fassin s'y emploie en mobilisant trois concepts : les formes de vie, les éthiques de la vie et les politiques de la vie. Dans la condition des réfugiés et des demandeurs d'asile, à travers le geste humanitaire et le sacrifice pour une cause, à la lumière des statistiques de mortalité et des modalités de calcul des indemnités de décès, à l'épreuve, enfin, d'une enquête généalogique et ethnographique, l'économie morale de la vie révèle de troublantes tensions dans la manière dont les sociétés contemporaines traitent les êtres humains. Une fois assemblées, comme dans un puzzle, les pièces de cette composition anthropologique, une image apparaît : celle, troublante, des vies inégales.