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What genes can't do
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ISBN: 0262280272 0585441618 9780262280273 9780585441610 026213411X 9780262134118 0262632977 9780262632973 Year: 2003 Publisher: Cambridge, Mass. MIT Press

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Abstract

"The idea of the gene has been a central organizing theme in contemporary biology; and the Human Genome Project and biotechnological advances have put the gene in the media spotlight. In this book Lenny Moss reconstructs the history of the gene concept, placing it in the context of the perennial interplay between theories of preformationism and theories of epigenesis. He finds that there are not one, but two, fundamental - and fundamentally different - senses of "the gene" in scientific use: one the heir to preformationism and the other the heir to epigenesis. "Gene-P," the preformationist gene concept, serves as an instrumental predictor of phenotypic outcomes, whereas "Gene-D," the gene of epigenesis, is a developmental resource that specifies possible amino acid sequences for proteins. Moss argues that the popular idea that genes constitute blueprints for organisms is the result of an unwarranted conflation of these independently valid senses of the gene, and he analyzes the rhetorical basis of this conflation." "In the heart of the book, Moss uses the Gene-D/Gene-P distinction to examine the real basis of biological order and of the pathological loss of order in cancer. He provides a detailed analysis of the "order-from-order" role of cell membranes and compartmentalization and considers dynamic approaches to biological order such as that of Stuart Kauffman. He reviews the history of cancer research with an emphasis on the oncogene and tumor suppressor gene models and shows how these gene-centered strategies point back to the significance of higher level, multicellular organization fields in the onset and progression of cancer. Finally, Moss draws on the findings of the Human Genome Project, biological modularity, and the growing interest in resynthesizing theories of evolution and development to look beyond the "century of the gene" toward a rebirth of biological understanding."--Jacket.


Periodical
Natural sciences.
ISSN: 26986248 Year: 2021 Publisher: Weinheim, Germany : Wiley-VCH GmbH,


Book
A dictionary of genetics
Authors: --- ---
ISBN: 1429440252 9781429440257 9780199891429 0199891427 9780195307610 Year: 2006 Publisher: Oxford New York Oxford University Press


Book
Introduction to nanoscience
Author:
ISBN: 1282383825 9786612383823 0191562556 9780191562556 6612383828 9780199544202 0199544204 9780199544219 0199544212 1383045097 Year: 2023 Publisher: Oxford : Oxford University Press,

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Abstract

This introductory nanoscience text integrates the physics, chemistry and biology of this new discipline. Each topic is treated assuming no background, but a conceptual emphasis and numerous examples and problems lead the reader to make contact with current research literature.

Joseph Leidy : the last man who knew everything
Author:
ISBN: 0585359733 9780585359731 0300073593 Year: 1998 Publisher: New Haven, CT : Yale University Press,


Book
Oxford dictionary of biochemistry and molecular biology
Author:
ISBN: 1280375833 9786610375837 0191545066 0585484058 9780191545061 9780585484051 Year: 2003 Publisher: [Place of publication not identified] Oxford University Press

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Abstract

This revised edition provides a survey of current biochemistry and molecular biology in the form of a dictionary. It contains short but informative entries arranged under more than 17,000 headwords. It is intended as a handy reference of first resource for those seeking information outside their immediate knowledge area or for those who need to refresh their memory of fundamental knowledge. This revised edition has been fully up-dated in order to include the new information that has been discovered since the original edition was published in 1997.

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