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"Forensic Genetic Approaches for Identification of Human Skeletal Remains: Challenges, Best Practices, and Emerging Technologies provides best practices on processing bone samples for DNA testing. The book outlines forensic genetics tools that are available for the identification of skeletal remains in contemporary casework and historical/archaeological investigations. Although the book focuses primarily on the use of DNA for direct identification or kinship analyses, it also highlights complementary disciplines often used in concert with genetic data to make positive identifications, such as forensic anthropology, forensic odontology, and forensic art/sculpting. Unidentified human remains are often associated with tragic events, such as fires, terrorist attacks, natural disasters, war conflicts, genocide, airline crashes, homicide, and human rights violations under oppressive totalitarian regimes. In these situations, extensive damage to soft tissues often precludes the use of such biological samples in the identification process. In contrast, bone material is the most resilient, viable sample type for DNA testing. DNA recovered from bone often is degraded and in low quantities due to the effects of human decomposition, environmental exposure, and the passage of time. The complexities of bone microstructure and its rigid nature make skeletal remains one of the most challenging sample types for DNA testing."--Provided by publisher.

Forensic genetics --- Forensic biology --- Genetics --- Medical jurisprudence --- Forensic genetics. --- Forensic osteology. --- Medicolegal osteology --- Osteology, Forensic --- Forensic anthropology --- Bone and Bones --- Forensic Genetics --- Forensic Anthropology --- Technique.

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Orthopedics --- Orthopedics. --- Orthopedics. --- Orthopedic Procedures --- Osteology --- Orthopaedics --- Orthopedia --- Surgery

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Orthopedics --- Orthopedics. --- Orthopedic Procedures --- Osteology --- Orthopaedics --- Orthopedia --- Surgery

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Bones --- Joints --- Osteology --- Musculoskeletal system --- Bone --- Skeleton --- Infections.

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This book identifies and analyzes the genetic basis of bone disorders in humans and demonstrates the utility of mouse models in furthering the knowledge of mechanisms and evaluations of treatments. The book is aimed at all students of bone biology and genetics, and with this in mind, it includes general introductory chapters on genetics and bone biology and more specific disease-orientated chapters, which comprehensively summarize the clinical, genetic, molecular genetic, animal model, functional and molecular pathology, diagnostic, counselling and treatment aspects of each disorder.