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Practical Preimplantation Genetic Diagnosis
Authors: ---
ISBN: 1280427590 9786610427598 1846281393 1852339209 Year: 2005 Publisher: London : Springer London : Imprint: Springer,

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Abstract

Although treatment is the major goal in the control of genetic disease, this is not yet a reality for most of inherited conditions. Even with the dramatic advancement in field of gene therapy, there are unfortunately not enough success stories to allow us to predict its impact in the near future. Preimplantation genetic diagnosis (PGD) offers the answer to the control of these inherited conditions by predicting reproductive outcome. It is no longer an experimental procedure, having become an integral part of genetic practices and assisted reproduction technology. This practical book is a vital new addition to the literature for fertility clinicians providing a comprehensive description of available experience, indications, methods and clinical outcomes. The authors of this book, from the Reproductive Genetics Institute in Chicago, USA, are among the leaders in this break-through field. Within this book, they instruct readers of the core features of the practice of PGD, while also providing incredibly detailed instructions of the genetics of a wide variety of common and not so common disorders that can be identified with the technique. This thorough and illuminating coverage ensures that this is the definitive reference book for those fertility specialists wishing to set up or already run a PGD clinic.

Maternal-fetal medicine
Authors: ---
ISBN: 0721676057 9780721676050 Year: 1999 Publisher: Philadelphia (Pa.): Saunders

Genetics in human reproduction
Authors: ---
ISBN: 184014825X 9781840148251 Year: 1999 Publisher: Aldershot: Brookfield, Vt.: Ashgate,

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Addresses ethical issues such as: the effects of the technicalization of reproduction; the moral status of the embryo; the validity of protecting the human genome; the concept of disease in genetic diagnosis and therapy and aspects of distributive justice. (Ashgate) This is the second edited volume from the European Network for Biomedical Ethics. It deals with interdisciplinary approaches to pre-implantation diagnosis (PID) and germline gene therapy across the fields of medicine, human genetics, philosophy, theology and social science. It addresses ethical issues such as: the effects of the technicalisation of reproduction; the moral status of the embryo; the validity of protecting the human genome; the concept of dissease in genetic diagnosis and therapy; and aspects of distributive justice.


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Practical Preimplantation Genetic Diagnosis
Authors: ---
ISBN: 1447140893 9786613934383 1447140907 1283621932 Year: 2013 Publisher: London : Springer London : Imprint: Springer,

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Abstract

Although treatment remains the major goal in the control of genetic disease, this is not yet a reality for most inherited conditions. In the absence of radical treatment, preimplantation genetic diagnosis (PGD) offers the answer to the control of these inherited conditions by predicting reproductive outcome. PGD is now entering its third decade as an established procedure for genetic and assisted reproduction practices, with new and exciting developments changing the whole concept of prevention of congenital disorders. The availability of practical experience from tens of thousands of PGD cases makes it necessary to update the current information on its accuracy, reliability and safety.  The Second Edition of this successful book updates the progress in prevention of genetic disorders to demonstrate the important place of PGD in primary preventive measures and its increasing role in providing the whole range of reproduction options to couples at risk. In addition, it provides an extensive review of the most recent developments within the field of PGD including, PGD for expanding indications, such as de novo mutations, cancers, inherited cardiac diseases and combined PGD for single gene disorders, HLA typing and 24 chromosome testing in patients of advance reproductive age. This practical book is vital for all practitioners within the field of fertility, reproductive medicine and medical genetics. It will also be useful for those responsible for planning and organizing PGD services and provides a working manual for the establishment and performance of PGD in the framework of IVF and genetic practices.  .


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L'eugénisme, la science et le droit
Author:
ISBN: 2130638503 Year: 2001 Publisher: Paris (6, avenue Reille 75685) : P.U.F.,

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Depuis quelques années, un débat virulent se développe autour de questions relevant de la bioéthique, des techniques de procréation et du diagnostic des maladies génétiques. L'eugénisme constitue l'un des éléments récurrents, et fondamentaux, de ce dialogue complexe entre les sciences exactes, la médecine, le droit et l'éthique. Néanmoins, si l'on entend prononcer nombre de mots savants, mais également une profusion de jugements moraux et de discours catastrophistes, il est difficile pour le grand public de savoir de quoi on parle&nbsp;: qu'est-ce précisément que l'eugénisme&nbsp;? Comment définir d'une manière claire et univoque cette démarche qui désigne étymologiquement «&nbsp;l'amélioration de l'humanité dans ses caractères transmissibles aux générations suivantes&nbsp;»&nbsp;? C'est à ce sujet peu connu, qui évoque pour nos contemporains les méthodes de la barbarie nazie mais concerne en fait toute la société, que cet ouvrage consacre une étude extrêmement complète, riche d'arguments historiques, juridiques, philosophiques et scientifiques.


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Signs and symptoms of genetic conditions : a handbook
Authors: ---
ISBN: 0199353077 0199388695 9780199388691 9781306731331 130673133X 019993097X 9780199930975 Year: 2014 Publisher: New York, New York : Oxford University Press,

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Connecting an abnormal physical exam to a possible genetic condition is a daunting and inexact task for any physician, be they a primary care provider, non-geneticist specialist, or fellowship-trained geneticist. Comprising 31 clinical protocols from the world's foremost clinical geneticists, Signs and Symptoms of Genetic Conditions provides a practical manual for the diagnosis and management of common human genetic conditions based on their presenting signs and/or symptoms. Each chapter examines a specific clinical finding and leads the user through a step-by-step approach to a differential d


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Creasy and Resnik's maternal-fetal medicine : principles and practice
Authors: --- --- --- --- --- et al.
ISBN: 0323479103 9780323479103 Year: 2019 Publisher: Philadephia Elsevier

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"Long recognized as the authoritative leader in the field, Creasy and Resnik's Maternal-Fetal Medicine, 8th Edition, continues to provide the latest evidence-based guidelines for obstetric and neonatal management, helping you minimize complications and offer patients the best possible care. Written by renowned experts in obstetrics, gynecology, and perinatology, this comprehensive resource has been thoroughly updated and reflects new information in every area, including recent tremendous advances in genetics, imaging, and more"--Publisher's description.

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