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Lung Cancer remains a major cause of death in of both women and men in our society. Lung cancer treatment paradigms have changed enormously as we’ve started to understand the genetic complexity and the multiple driver mutations influencing the disease. Therapeutics directed towards, or to inhibit signaling pathways has resulted in increased life spans for our patients. Over the last two decades, we have gone from simple chemotherapy used to treat all, to a personalized medicine approach for the majority. For non-small cell lung cancer patients without driver mutations, the world of immune oncology has arrived. These improved long-term outcomes mean that now our lung cancer patients can live with their cancers, but without progression. The aim of this book is to catalogue the current state of knowledge for the many facets of advanced lung cancer. It describes current treatment approaches for driver mutations, rare mutations, and rare thoracic malignancies such as neuroendocrine tumors. Most importantly, this book addresses the topics of palliative treatment and care which allow our patients to enjoy longer survival with the highest quality of life. We hope you enjoy this e-book. The future is brighter for lung cancer patients and as lung cancer specialists; we finally feel sense optimism about treatment options for our patients.

Updates on Diagnoses and Treatments --- Metastatic NSCLC

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"In inter-war Sweden, the psychiatric diagnosis of psychopathy served as a controversial but powerful tool for the management of people who failed to live up to contemporary civic ideals. The diagnosis was based on theories of a broad spectrum of biologically-based disorders in the borderland between normality and actual mental illness. The disturbances were assumed to manifest themselves as, for example, homosexuality, hysterical attacks, emotional coldness, mythomania, or restlessness.Another controversial diagnosis was paranoia querulans or querulous paranoia, a disease that was linked to the emergence of the modern state and its rule of law, and thought to manifest itself mainly in hyperbolic complaints against supposed wrongdoings. Thus, the disorder implicated an excessive use of one's civil rights. A particular dilemma related to this disease was that the kind of behaviour that had usually led to the diagnosis and subsequent psychiatric confinement, namely a ardent manner of writing letters to public authorities, was precisely what was required for discharge.In De samhällsbesvärliga (The Social Troublemakers), historian of science and ideas Annika Berg examines how patients described as psychopaths or querulants could negotiate for discharge with doctors and authorities in 1930s and 40s Sweden. This was a period in time when the system of psychiatric care in Sweden was greatly expanded in answer to a perceived shortage, but was also transformed into a somewhat more open apparatus with possibilities to apply for preliminary discharge and other forms of outpatient solutions. It was also a time when psychiatry was under attack from different quarters, and psychiatrists were accused of using flexible diagnoses such as psychopathy to confine people wrongly. Against this backdrop, how did the management of psychopaths and querulants fit with contemporary ideals of citizenship and democracy? How did the patients view themselves? And how were negotiations in individual cases affected by notions of, for example, class, gender and sexuality?"

Psychiatry --- Psychopathy --- Paranoia querulans --- Diagnoses --- confinement --- intersectionality

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Diagnosis, Differential. --- Internal Medicine. --- Medicine, Internal --- Diagnoses, Differential --- Differential Diagnoses --- Differential Diagnosis --- Diagnosis, Differential --- Internal Medicine

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Diagnosis, Differential. --- Skin Diseases --- Diagnoses, Differential --- Differential Diagnoses --- Differential Diagnosis --- diagnosis. --- pathology. --- Diagnosis, Differential --- diagnosis --- pathology

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Uveitis --- Diagnosis, Differential. --- diagnosis. --- therapy. --- Diagnoses, Differential --- Differential Diagnoses --- Differential Diagnosis --- Uvea --- Eye --- Inflammation --- Diseases