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Computational Biology --- Genomics --- Databases, Genetic. --- Software. --- Genetics --- Bioinformatics --- Génétique --- Bio-informatique --- methods. --- Data processing --- Informatique --- 57.087 --- Methods and techniques for parameter estimation. Recording of biological data --- Bioinformatics. --- Data processing. --- 57.087 Methods and techniques for parameter estimation. Recording of biological data --- Génétique --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Bio-informatics --- Biological informatics --- Information science --- Computational biology --- Systems biology
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With the continuing advances in sequencing technologies and the availability of thousands of distinct human genomes, we are fast approaching the day when "personal genomes" become a standard study measure and a routine component of personal health records. In Genetic Variation: Methods and Protocols, expert researchers address the rising importance of genome variation, both at the level of the individual and in population-based studies of disease, with a collection of detailed protocols reflecting the nature and impact of genetic variation on human phenotypes. The contributions cover a majority of the most important forms of genetic variation studied today, including single nucleotide polymorphisms (SNPs), insertions/deletion (indels), copy number variation (CNVs), variable number tandem repeats (VNTRs), mitochondrial variation, mobile elements, and epigenetic variation. As a volume in the highly successful Methods in Molecular Biology™ series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Convenient and cutting-edge, Genetic Variation: Methods and Protocols aims to bring bench scientists, clinicians, and bioinformaticians together in order to aid progress toward a greater understanding of the full impact of variation on human health and disease.
Biochemistry. --- Human genetics. --- Gene expression. --- Biochemistry, general. --- Human Genetics. --- Gene Expression. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Genes --- Genetic regulation --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Composition --- Expression
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Bioinformatics for Geneticists describes a step by step approach to key bioinformatics and genetic analysis procedures, based upon practical experience gained after many years of direct bioinformatics support for laboratory geneticists. It features detailed case studies of problems and analytical approaches that are specific to the needs of the genetics researcher. The book contains reviews of bioinformatics tools and genetic databases. Each chapter is written to capture the principles of analysis regardless of the tool used, thereby ensuring that the book stays relevant as new data and tools become available. As the first book specifically addressing the informatics requirements of geneticists, Bioinformatics for Geneticists is essential reading for all those engaged in genetic research and should prove indispensable for both the planning and analysis of such studies. The book provides in-depth coverage of the underlying principles of both genetic and bioinformatic analysis which should make this book suitable for all students of genetics or bioinformatics. The book takes a web-based approach to bioinformatics, suitable for bot h internet novices and more experienced web users. The focus is on public software tools and databases freely available to all. The editors and authors bring a broad range of experience from academic and industrial genetics research environments. The book is accessible to individuals outside the immediate field of molecular genetics, e.g. statisticians, epidemiologists and physicians who wish to improve their knowledge of bioinformatics and genetics. This is currently the only book specifically aimed at the bioinformatics needs and priorities of genetics researchers.
575.113 <035> --- 57.087 --- 577.212.3 --- 577.212.3 Nucleic acid base and sequence compositon. Experimental deciphering of genetic code. --- Nucleic acid base and sequence compositon. Experimental deciphering of genetic code. --- 575.113 <035> Gene. Genetic apparatus. Genome--Grote handboeken. Compendia --- Gene. Genetic apparatus. Genome--Grote handboeken. Compendia --- Methods and techniques for parameter estimation. Recording of biological data. Bioinformatics --- Bioinformatics --- Genetics --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Bio-informatics --- Biological informatics --- Information science --- Computational biology --- Systems biology --- Data processing --- Nucleic acid base and sequence compositon. Experimental deciphering of genetic code --- genetica --- moleculaire biologie --- Molecular biology --- Bioinformatics. --- Data processing. --- bio-informatica
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