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This book explores how PPPM, clinical practice, and basic research could be best served by information technology (IT). A use-case was developed for hepatocellular carcinoma (HCC). The subject was approached with four interrelated tasks: (1) review of clinical practices relating to HCC; (2) propose an IT system relating to HCC, including clinical decision support and research needs; (3) determine how a clinical liver cancer center can contribute; and, (4) examine the enhancements and impact that the first three tasks will have on the management of HCC. An IT System for Personalized Medicine (ITS-PM) for HCC will provide the means to identify and determine the relative value of the wide number of variables, including clinical assessment of the patient -- functional status, liver function, degree of cirrhosis, and comorbidities; tumor biology, at a molecular, genetic and anatomic level; tumor burden and individual patient response; medical and operative treatments and their outcomes.

Medicine & Public Health. --- Health Informatics. --- Data Mining and Knowledge Discovery. --- Oncology. --- Hepatology. --- Simulation and Modeling. --- Medicine. --- Medical records --- Clinical medicine. --- Data mining. --- Computer simulation. --- Médecine --- Dossiers médicaux --- Médecine clinique --- Cancérologie --- Exploration de données (Informatique) --- Simulation par ordinateur --- Data processing. --- Informatique --- Liver -- Cancer -- Treatment. --- Liver -- Cancer. --- Medicine --- Health & Biological Sciences --- Medical & Biomedical Informatics --- Liver --- Medicine, Preventive. --- Personalized medicine. --- Cancer. --- Individualized medicine --- Disease prevention --- Diseases --- Prevention of disease --- Preventive medicine --- Hepatocellular carcinoma --- Prevention --- Health informatics. --- Medical care --- Pharmacogenetics --- Pathology --- Preventive health services --- Preventive medicine physicians --- Public health --- Oncology  . --- Medicine, Clinical --- Tumors --- Algorithmic knowledge discovery --- Factual data analysis --- KDD (Information retrieval) --- Knowledge discovery in data --- Knowledge discovery in databases --- Mining, Data --- Database searching --- EHR systems --- EHR technology --- EHRs (Electronic health records) --- Electronic health records --- Electronic medical records --- EMR systems --- EMRs (Electronic medical records) --- Information storage and retrieval systems --- Computer modeling --- Computer models --- Modeling, Computer --- Models, Computer --- Simulation, Computer --- Electromechanical analogies --- Mathematical models --- Simulation methods --- Model-integrated computing --- Gastroenterology --- Clinical informatics --- Health informatics --- Medical information science --- Information science --- Data processing

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Computer-assisted systems have long since penetrated the operating room. Their functions include pre and intraoperative imaging, image processing, modeling, simulation, navigation, and robotics. Computers help run the "surgical cockpit." They are critical in pre- and intraoperative process optimization, workflow management, and for information integration in the surgical suite. Computerassistierte Systeme haben längst Einzug in den Operationssaal gehalten, ohne solche Systeme sind bestimmte Interventionen in den großen chirurgischen Fächern mit dem heutigen Qualitätsanspruch nicht mehr denkbar. Trotzdem befinden wir uns erst am Anfang einer Entwicklung, die in der Zukunft weitere wichtige Neuerungen bereithält: Prä- und intraoperative Bildgebung, Bildverarbeitung, Modellierung, Simulation, Navigation, Robotik, Surgical Cockpit, prä- und intraoperative Prozessoptimierung, Workflow Management und Informationsintegration im OP werden in den nächsten Jahren an Bedeutung gewinnen. Was steckt hinter diesen Begriffen? Ändert sich durch diese Entwicklungen das Berufsbild des Chirurgen? Welche ökonomischen, rechtlichen und ethischen Aspekte sind zu beachten? Ausgewiesene Experten geben in diesem Buch Antworten auf diese Fragen.

Computer-assisted surgery. --- Surgery --- Surgery, Primitive --- Medicine --- Computer-aided surgery --- Image-guided surgery --- Data processing. --- . --- Computerassistierte Systeme. --- Digitaler OP. --- Modellierung. --- Operation. --- Robotik. --- Simulation.