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This book discusses the main stem cell niches under distinct pathophysiological conditions. The role of tissue microenvironments in stem cell regulation, as well as modern methodologies and new techniques for the identification and characterization of stem cell niches, are discussed by leading experts in the field. Chapters describe the major components of various stem cell microenvironments, such as cellular components, soluble factors, cell-cell interactions, extra-cellular matrix proteins, and physical forces. Stem Cell Microenvironments and Beyond is part of the highly successful Advances in Experimental Medicine and Biology series. It is essential reading for graduate students and researchers in the field of stem cells or cell biology as well as clinicians.

Life sciences. --- Cancer research. --- Stem cells. --- Regenerative medicine. --- Tissue engineering. --- Life Sciences. --- Stem Cells. --- Regenerative Medicine/Tissue Engineering. --- Cancer Research. --- Biomedical engineering --- Regenerative medicine --- Tissue culture --- Medicine --- Regeneration (Biology) --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Cells --- Cancer research --- Biosciences --- Sciences, Life --- Science --- Stem cells --- Research. --- Oncology. --- Tumors

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The present book is an attempt to describe the most recent developments in the area of pericyte biology which is one of the emergent hot topics in the field of molecular and cellular biology today. Here, we present a selected collection of thirteen detailed chapters on what we know so far about pericytes in distinct organs in physiological and pathological conditions. Further, it provides an update on the most novel functions attributed to these cells and will introduce a newer generation of researchers and scientists to the importance of these cells, ranging from their discovery in different organs through current state-of-the-science. It will be invaluable for both advanced cell biology students as well as researchers in cell biology, stem cells and vascular research. This volume explores pericytes' physiologic roles in different tissues, ranging from the pancreas, lungs and liver through skeletal muscle, gut, retina and more. Together with its companion volumes Pericyte Biology in Disease and Pericyte Biology – Novel Concepts, Pericyte Biology in Different Organs presents a comprehensive update on the latest information and most novel functions attributed to pericytes. To those researchers newer to this area, it will be useful to have the background information on these cells' unique history. It will be invaluable for both advanced cell biology students as well as researchers in cell biology, stem cells and researchers or clinicians involved with specific organs. .

Epithelial cells. --- Cells --- Epithelium --- Exfoliative cytology --- Stem cells. --- Oncology. --- Stem Cells. --- Regenerative Medicine/Tissue Engineering. --- Cancer Research. --- Regenerative medicine. --- Tissue engineering. --- Cancer research. --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Cancer research --- Biomedical engineering --- Regenerative medicine --- Tissue culture --- Medicine --- Regeneration (Biology)

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This book presents a comprehensive discussion on the heterogeneity existing between different types of stem cells within the same tissue, for several types of cancers, e.g. glioblastoma stem cells. Recent developments have revealed completely different roles of distinct stem cells within the same organ. Thus, Stem Cells Heterogeneity in Cancer provides a timely update us on the current information on stem cells heterogeneity in various tissues. It also provides a solid foundation of the history of stem cells from specific tissues and the current applications of this knowledge in regenerative medicine. When taken as a whole, alongside its companion volumes Stem Cells Heterogeneity – Novel Concepts, and Stem Cells Heterogeneity in Different Organs, these three books present a comprehensive reference on stem cell heterogeneity in various tissues and current and future applications for regenerative medicine. It is essential reading for advanced cell biology students as well as researchers in stem cells and clinicians. .

Cancer cells. --- Stem cells. --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Cells --- Pathology, Cellular --- Oncology. --- Cell cycle. --- Stem Cells. --- Regenerative Medicine/Tissue Engineering. --- Cancer Research. --- Cell Cycle Analysis. --- Mitotic cycle --- Nuclear cycle (Cytology) --- Biological rhythms --- Tumors --- Regenerative medicine. --- Tissue engineering. --- Cancer research. --- Cancer research --- Biomedical engineering --- Regenerative medicine --- Tissue culture --- Medicine --- Regeneration (Biology)

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This book presents a comprehensive discussion on the heterogeneity existing between different types of stem cells within the same tissue. As the functions of these stem cells vary, this is very important for the application of stem cells in cell therapy. This book describes the many recent developments that have revealed completely different roles of distinct stem cells within the same organ. Stem Cells Heterogeneity in Different Organs provides a timely update on the current information on stem cells heterogeneity in various tissues. It also provides a solid foundation of the history of stem cells from specific tissues and the current applications of this knowledge in regenerative medicine. Taken with its companion volumes, Stem Cells Heterogeneity: Novel Concepts and Stem Cells Heterogeneity in Cancer, this book is essential reading for advanced cell biology students as well as researchers and clinicians working with stem cells.

Stem cells. --- Regenerative medicine. --- Tissue engineering. --- Cell cycle. --- Stem Cells. --- Regenerative Medicine/Tissue Engineering. --- Cell Cycle Analysis. --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Cells --- Mitotic cycle --- Nuclear cycle (Cytology) --- Biological rhythms --- Biomedical engineering --- Regenerative medicine --- Tissue culture --- Medicine --- Regeneration (Biology)

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This volume discusses recent research advances in cancer biology, focusing on the role of the tumor microenvironment. Taken alongside its companion volumes, Tumor Microenvironment: Recent Advances covers the latest research on various aspects of the tumor microenvironment, as well as future directions. Useful for introducing the newer generation of researchers to the history of how scientists studied the tumor microenvironment as well as how this knowledge is currently applied for cancer treatments, it will be essential reading for advanced cell biology and cancer biology students, as well as researchers seeking an update on research on the tumor microenvironment.

Cancer research. --- Stem cells. --- Regenerative medicine. --- Tissue engineering. --- Cancer Research. --- Stem Cells. --- Regenerative Medicine/Tissue Engineering. --- Cancer --- Research. --- Cancer research --- Biomedical engineering --- Regenerative medicine --- Tissue culture --- Medicine --- Regeneration (Biology) --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Cells