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Methodologies used to analyse the genomes of prokaryotes and eukaryotes are advancing very rapidly as it has been realized that there is a resolution gap between what can be viewed under the microscope and what molecular techniques can resolve. This book presents current, successful strategies for construction of physical maps to identify and analyse the arrangement and function of genes. These techniques, which are applicable to a range of organisms, are being used to move from linked markers to candidate genes in several human monogenic disorders. They are presented in a way that should enable any research or diagnostic laboratory to apply them to their particular systems. Also included are descriptions of new probes and approaches for the localization of human disorders whose analysis has so far eluded the molecular geneticist.

Chromosome mapping --- Chromosome Mapping --- Chromosomes --- Technique --- cartes --- Gene mapping --- -Chromosome mapping --- Genetic mapping --- Genome mapping --- Linkage mapping (Genetics) --- Mapping, Gene --- Genetics --- Chromosome Mapping. --- Basic Sciences. Bioinformatics --- Technique. --- Genome informatics --- -Technique --- Genome informatics.

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DNA --- Genetic Diseases, Inborn --- ds-DNA --- DNA, Double-Stranded --- Deoxyribonucleic Acid --- DNA, Double Stranded --- Double-Stranded DNA --- ds DNA --- Biopolymers --- diagnostic use. --- diagnosis. --- Genetic Technics --- Hereditary Diseases --- Génétique médicale --- diagnostic use --- Genetic Techniques. --- diagnosis --- Human genetics --- Medical genetics --- Génétique médicale

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West Indies --- History.

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