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Although the efficiency of chemical pesticides is no longer to be proven, evidence has underlined their non-sustainability. Biocontrol agents (BCAs), including plant growth-promoting rhizobacteria (PGPRs) and their bioactive secondary metabolites (BSMs), are among the most promising alternatives to chemicals for sustainable agriculture. Bacillus velezensis has appeared as a model PGPR for plant protection due to its competence in synthesizing a large spectrum of BSMs. Besides non-ribosomal BSMs (NR-BSMs), ribosomally synthesized and post-translationally modified peptides (RiPPs) are essential for the biocontrol potential of model species such as B. velezensis. However, in contrast to the well-characterized NR-BSMs, efforts are still required to increase our knowledge on RiPPs in terms of diversity, regulation of expression and activity.

Bacillus velezensis --- GA1 --- Lanthipeptide --- Lantibiotic --- Hadrilysin --- Bacteriocin --- RiPP --- Biocontrol --- PGPR --- BSM --- Gene regulation --- Global regulator --- amylolysin --- Sciences du vivant > Agriculture & agronomie --- Sciences du vivant > Microbiologie --- Sciences du vivant > Biochimie, biophysique & biologie moléculaire --- Sciences du vivant > Génétique & processus génétiques