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Plants produce a vast number of bioactive compounds with different chemical scaffolds, which modulate a diverse range of molecular targets and are used as drugs for treating numerous diseases. Most present-day medicines are derived either from plant compounds or their derivatives, and plant compounds continue to offer limitless reserves for the discovery of new medicines. While different classes of plant compounds, like phenolics, flavonoids, saponins and alkaloids, and their potential pharmacological applications are currently being explored, their curative mechanisms are yet to be understood in detail. This book is divided into 2 volumes and offers detailed information on plant-derived bioactive compounds, including recent research findings. Volume 1, Plant-derived Bioactives: Chemistry and Mode of Action, discusses the chemistry of highly valued plant bioactive compounds and their mode of actions at the molecular level. Volume 2, Plant-derived Bioactives: Production, Properties and Therapeutic Applications, explores the sources, biosynthesis, production, biological properties and therapeutic applications of plant bioactives. Given their scope, these books are valuable resources for members of the scientific community wishing to further explore various medicinal plants and the therapeutic applications of their bioactive compounds. They appeal to scholars, teachers and scientists involved in plant product research, and facilitate the development of innovative new drugs. .

Plant biochemistry. --- Plant physiology. --- Plant anatomy. --- Plant development. --- Plant breeding. --- Plant Biochemistry. --- Plant Physiology. --- Plant Anatomy/Development. --- Plant Breeding/Biotechnology. --- Crops --- Agriculture --- Breeding --- Development of plants --- Plant development --- Developmental biology --- Growth (Plants) --- Plants --- Botany --- Plant structure --- Structural botany --- Vegetable anatomy --- Anatomy --- Physiology --- Phytochemistry --- Plant biochemistry --- Plant chemistry --- Biochemistry --- Phytochemicals --- Plant biochemical genetics --- Ontogeny --- Structure --- Plant bioactive compounds. --- Bioactive compounds --- Plant products --- Fitoquímica --- Fisiologia vegetal --- Botànica --- Absorció de l'aigua en les plantes --- Assimilació de les plantes --- Creixement (Plantes) --- Ecofisiologia vegetal --- Fecundació de les plantes --- Fisiologia postcollita --- Ritmes biològics en les plantes --- Floració --- Germinació --- Metabolisme de les plantes --- Moviments de les plantes --- Nutrició vegetal --- Reproducció de les plantes --- Respiració de les plantes --- Saprofitisme --- Tropisme --- Biologia molecular vegetal --- Bioquímica de les plantes --- Bioquímica vegetal --- Botànica química --- Química botànica --- Química de les plantes --- Química vegetal --- Bioquímica --- Hormones vegetals --- Pigments vegetals --- Proteïnes vegetals

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This book provides a comprehensive reference for various plant bioactive compounds for research and pharmacological significance across the entire spectrum of phytochemical genomics. The book opens with general information on diversity, analysis and genomic basis of phytochemicals, computational approaches, databases for responsible genes, and biosynthetic pathways, and it delves very much into the details behind phytochemical diversity and diverse roles of plant metabolites. The later parts of the book also explore the direct drug discovery and omics approaches including metabolomics, transcriptomics, as well as gene editing technology experiments to further inspire readers into its unlimited potentials. Each chapter includes detailed analysis and relevant experiments for better and deeper understanding of the concepts. The book will be an invaluable aid for medicinal plant researchers and a rich source of information and advice for advanced undergraduates and graduates in the fields of medicine, nutraceuticals, cosmetics, flavor, and fragrance studies.

Botany. --- Genetics. --- Biology—Technique. --- Biology. --- Molecular biology. --- Biochemistry. --- Phytochemicals --- Genome, Plant. --- Plants, Medicinal --- Plant Science. --- Genetics and Genomics. --- Biological Techniques. --- Biological Sciences. --- Molecular Biology. --- Chemical Biology. --- genetics. --- Plant Genome --- Genomes, Plant --- Plant Genomes --- Genes, Plant --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Botanical science --- Floristic botany --- Phytobiology --- Phytography --- Phytology --- Plant biology --- Plant science --- Natural history --- Plants --- Life sciences --- Life (Biology) --- Composition --- Fitoquímica --- Genètica molecular vegetal

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Cancer is one of the leading death cause of human population increasingly seen in recent times. Plants have been used for medicinal purposes since immemorial times. Though, several synthetic medicines are useful in treating cancer, they are inefficient and unsafe. However, plants have proved to be useful in cancer cure. Moreover, natural compounds from plants and their derivatives are safe and effective in treatment and management of several cancer types. The anticancer plants such as Catharanthus roseus, Podophyllum peltatum, Taxus brevifolia, Camptotheca acuminate, Andrographis paniculata, Crateva nurvala, Croton tonkinensis, Oplopanax horridus etc., are important source of chemotherapeutic compounds. These plants have proven their significance in the treatment of cancer and various other infectious diseases. Nowadays, several well-known anticancer compounds such as taxol, podophyllotoxins, camptothecin, vinblastine, vincristine, homoharringtonine etc. have been isolated and purified from these medicinal plants. Many of them are used effectively to combat cancer and other related diseases. The herbal medicine and their products are the most suitable and safe to be used as an alternative medicine. Based on their traditional uses and experimental evidences, the anticancer products or compounds are isolated or extracted from the medicinally important plants. Many of these anticancer plants have become endangered due to ruthless harvesting in nature. Hence, there is a need to conserve these species and to propagate them in large scale using plant tissue culture. Alternatively, plant cell tissue and organ culture biotechnology can be adopted to produce these anticancer compounds without cultivation. The proper knowledge and exploration of these isolated molecules or products could provide an alternative source to reduce cancer risk, anti-tumorigenic properties, and suppression of carcinogen activities. Anticancer plants: Volume 1, Properties and Application is a very timely effort in this direction. Discussing the various types of anticancer plants as a source of curative agent, their pharmacological and neutraceutical properties, cryo-preservations and recent trends to understand the basic cause and consequences involved in the diseases diagnosis. We acknowledge the publisher, Springer for their continuous inspiration and valuable suggestions to improvise the content of this book. We further extend our heartfelt gratitude to all our book contributors for their support, and assistance to complete this assignment. I am sure that these books will benefit the scientific communities including academics, pharmaceuticals, nutraceuticals and medical practitioners. .

Medicinal plants. --- Life sciences. --- Cancer research. --- Agriculture. --- Proteomics. --- Plant physiology. --- Life Sciences. --- Plant Physiology. --- Plant Genetics and Genomics. --- Cancer Research. --- Botany --- Plants --- Physiology --- Molecular biology --- Proteins --- Farming --- Husbandry --- Industrial arts --- Life sciences --- Food supply --- Land use, Rural --- Cancer research --- Biosciences --- Sciences, Life --- Science --- Drug plants --- Plants, Useful --- Botanical drug industry --- Botany, Medical --- Materia medica, Vegetable --- Psychotropic plants --- Plant genetics. --- Oncology. --- Tumors --- Genetics

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This book summarizes the application of plant derived anticancer compounds as chemopreventives to treat several cancer types, focusing on the molecular mechanisms of action of phytocompounds and providing an overview of the basic processes at the cellular and molecular level that are involved in the progression of the cancer and can be employed in targeted preventive therapies. In addition, it highlights the development of novel anticancer drugs from plant sources using bioinformatics approaches. The compiled chapter data aids readers understanding of issues related to bioavailability, toxic effects and mechanisms of action of phytocompounds, and helps them identify the leads and utilize them against various cancer types effectively. Furthermore, it promotes the use of bioinformatics tools in medicinal plants to expedite their use in plant breeding programs to develop molecular markers to distinguish disease subtypes and predicting mutation, which in turn improves cancer diagnosis and prognosis, and to develop new lead compounds computationally. Thebook provides scientific verifications of plant compounds mechanisms of action against various cancers and offers useful information for students, teachers, and healthcare professionals involved in drug discovery, and clinical and therapeutic research. .

Medicinal plants. --- Antineoplastic agents. --- Plant physiology. --- Proteomics. --- Agriculture. --- Plant genetics. --- Plant Physiology. --- Plant Genetics and Genomics. --- Plants --- Genetics --- Farming --- Husbandry --- Industrial arts --- Life sciences --- Food supply --- Land use, Rural --- Molecular biology --- Proteins --- Botany --- Physiology

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Nature has consistently provided human beings with bioactive compounds that can be used directly as drugs or indirectly as drug leads. Some of the major classes of natural bioactive compounds include phenolics, alkaloids, tannins, saponins, lignin, glycosides, terpenoids, and many more. They possess a broad range of biological activities and are primarily useful in the treatment of various health issues. At the same time, the search for new and novel drugs is never-ending and, despite major advances in synthetic chemistry, nature remains an essential resource for drug discovery. Therefore, more and more researchers are interested in understanding the chemistry, clinical pharmacology, and beneficial effects of bioactive compounds in connection with solving human health problems. This book presents a wealth of information on natural metabolites that have been or are currently being used as drugs or leads for the discovery of new drugs. In addition, it highlights the importance of natural products against various human diseases, and their applications in the drug, nutraceuticals, cosmetics and herbal industries. Accordingly, the book offers a valuable resource for all students, educators, and healthcare experts involved in natural product research, phytochemistry, and pharmacological research. .

Bioactive compounds. --- Biologically active compounds --- Compounds, Bioactive --- Compounds, Biologically active --- Compounds, Physiologically active --- Physiologically active compounds --- Chemicals --- Plant anatomy. --- Plant development. --- Plant physiology. --- Plant biochemistry. --- Plant genetics. --- Plant Anatomy/Development. --- Plant Physiology. --- Plant Biochemistry. --- Plant Genetics and Genomics. --- Plants --- Genetics --- Phytochemistry --- Plant biochemistry --- Plant chemistry --- Biochemistry --- Botany --- Phytochemicals --- Plant biochemical genetics --- Physiology --- Development of plants --- Plant development --- Developmental biology --- Growth (Plants) --- Plant structure --- Structural botany --- Vegetable anatomy --- Anatomy --- Ontogeny --- Structure