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The papers reported here will contribute to proposing new insights into the mechanisms of several conditions, as well as suggesting new diagnostic alternatives and therapeutic targets in widespread pathologies such inflammation and inflammatory-based diseases. The discovery of the new is, as always, anchored in recourse to the old.

toxicity --- long-lasting effect --- iso-?-acids --- ammonium glycyrrhizinate --- metabolomics --- cytokines --- Alnus sibirica --- energy metabolism --- curcumin --- antineuroinflammation --- nitric oxide --- antioxidant --- nutraceutical food --- liver --- nardochinoid B --- endometriosis --- adipose tissue --- Nardostachys chinensis --- tau --- macrophage --- nociception --- heme oxygenase-1 --- enzymatic hydrolysis --- IL-6 --- nuciferine --- docking --- chronic nonbacterial prostatitis --- black tea polyphenol --- network pharmacology --- Tagetes patula L. --- SEM --- lipopolysaccharide --- solid lipid nanoparticle --- tauopathy --- memory --- lupane-type triterpene --- acute lung injury --- inducible nitric oxide synthase --- inflammation --- anti-inflammatory --- microglia --- resveratrol --- theaflavins --- hirsutanonol --- short-term high-fat diet --- inflammatory disease --- juçara --- oregonin --- PPARs --- NF-?B --- neuroprotection --- Portulaca oleracea --- TNF-? --- depression