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Anionic annulations in organic synthesis : a versatile and prolific class of ring-forming reactions
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ISBN: 9780128138014 0128138017 9780128138007 0128138009 9780128138007 Year: 2019 Publisher: Amsterdam, The Netherlands : Elsevier,

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Anionic annulations in organic synthesis : a versatile and prolific class of ring-forming reactions
Author:
ISBN: 9780128138014 0128138017 Year: 2019 Publisher: Amsterdam Elsevier

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Anionic Annulations in Organic Synthesis: A Versatile and Prolific Class of Ring-Forming Reactions is a comprehensive review of the best annulations for the construction of cyclic structures and their applications in the total synthesis of functional molecules. The reactions described in the work are particularly useful for the synthesis of polyoxygenated polycyclic compounds, including tetracyclines, angucyclines, uncialamycins, and lignans, among other compounds. Included in detail are the Hauser, Robinson, Sammes and Meyers annulations, all of which can be effectively used to construct substrates with complex molecular structures. This work provides the tools to master anionic organic chemistry, ortho-lithiation, lateral lithaition/metalation and organic selectivity issues, like chemoselectivity, regioselectivity and stereoselectivity. This book is a valuable resource for organic chemists, researchers and students seeking a complete and detailed understanding of anionic annulations.

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