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Navigating safely through a wealth of genome, protein and metabolite information, as well as a host of information processing tools, without getting lost is crucial for successful research in – and teaching of - molecular biology. This concise, easy-to-follow textbook/guide serves as a valuable introduction to contemporary cell biology for readers and offers insight into the key research directions in the field. It begins with an overview of existing tools for finding, designing and investigating metabolic, genetic, signalling and other network databases. This practical guide then introduces Cell Illustrator®, a software tool for biological pathway modelling and simulation, developed by the authors. In-depth discussion reveals how this tool can be used for creating, analyzing and simulating biological models, thereby explicating and testing current understanding of basic biological processes. Readers do not require prior knowledge of differential equations or programming. Features: • Provides many helpful learning aids, such as detailed examples throughout, and exercises and solutions • Designed and structured to be part of a semester-long course • Discusses the computational functionalities required for Systems Biology • Addresses practical issues surrounding software tools • Introduces the current big bio-databases such as TRANSPATH® by Biobase, and explains why and how they can be used to develop and support systems biology research • Explains important pathway databases and software tools, together with their related concepts • Guides the reader to model pathways in a step-by-step and clear manner • Contains a Foreword written by Professor Andreas Dress, Director CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences Written for undergraduates, this reader-friendly introduction to the field of Systems Biology offers insight and teaches sound expertise in the subject. It will also prove valuable to graduate students and professionals wishing to develop and support their systems-biology research.
Computational biology. --- Electronic books. -- local. --- Systems biology. --- Systems biology --- Biology - General --- Biology --- Health & Biological Sciences --- Life sciences. --- Computer simulation. --- Bioinformatics. --- Cell biology. --- Life Sciences. --- Life Sciences, general. --- Computational Biology/Bioinformatics. --- Simulation and Modeling. --- Cell Biology. --- Bioinformatics --- Computational biology --- Biological systems --- Molecular biology --- Cytology. --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Computer modeling --- Computer models --- Modeling, Computer --- Models, Computer --- Simulation, Computer --- Electromechanical analogies --- Mathematical models --- Simulation methods --- Model-integrated computing --- Bio-informatics --- Biological informatics --- Information science --- Biosciences --- Sciences, Life --- Science --- Data processing
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Complex analysis --- Biology --- Computer science --- Programming --- Computer architecture. Operating systems --- Information systems --- Artificial intelligence. Robotics. Simulation. Graphics --- Computer. Automation --- complexe analyse (wiskunde) --- biologie --- computers --- informatica --- programmeren (informatica) --- informatietechnologie --- algoritmen --- KI (kunstmatige intelligentie)
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High-throughput sequencing and functional genomics technologies have given us the human genome sequence as well as those of other experimentally, medically, and agriculturally important species, thus enabling large-scale genotyping and gene expression profiling of human populations. Databases containing large numbers of sequences, polymorphisms, structures, metabolic pathways, and gene expression profiles of normal and diseased tissues are rapidly being generated for human and model organisms. Bioinformatics is therefore gaining importance in the annotation of genomic sequences; the understan
Bioinformatics --- Biology --- Data processing
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Bioinformatics --- Computational biology --- Biology --- Publication Formats --- Biological Science Disciplines --- Publication Characteristics --- Natural Science Disciplines --- Disciplines and Occupations --- Congresses --- Computational Biology --- Mechanical Engineering --- Engineering & Applied Sciences --- Health & Biological Sciences --- Computer Science --- Mechanical Engineering - General --- Genetics --- Information Technology --- Artificial Intelligence --- Life sciences. --- Computer programming. --- Data structures (Computer science). --- Computers. --- Algorithms. --- Artificial intelligence. --- Life Sciences. --- Life Sciences, general. --- Programming Techniques. --- Data Structures, Cryptology and Information Theory. --- Artificial Intelligence (incl. Robotics). --- Computation by Abstract Devices. --- Algorithm Analysis and Problem Complexity. --- AI (Artificial intelligence) --- Artificial thinking --- Electronic brains --- Intellectronics --- Intelligence, Artificial --- Intelligent machines --- Machine intelligence --- Thinking, Artificial --- Bionics --- Cognitive science --- Digital computer simulation --- Electronic data processing --- Logic machines --- Machine theory --- Self-organizing systems --- Simulation methods --- Fifth generation computers --- Neural computers --- Algorism --- Algebra --- Arithmetic --- Automatic computers --- Automatic data processors --- Computer hardware --- Computing machines (Computers) --- Electronic calculating-machines --- Electronic computers --- Hardware, Computer --- Computer systems --- Cybernetics --- Calculators --- Cyberspace --- Information structures (Computer science) --- Structures, Data (Computer science) --- Structures, Information (Computer science) --- File organization (Computer science) --- Abstract data types (Computer science) --- Computers --- Electronic computer programming --- Electronic digital computers --- Programming (Electronic computers) --- Coding theory --- Biosciences --- Sciences, Life --- Science --- Foundations --- Programming --- Computer science. --- Data structures (Computer scienc. --- Computer software. --- Data Structures and Information Theory. --- Artificial Intelligence. --- Informatics --- Software, Computer --- Rio de Janeiro <2010>
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This volume contains the papers presented at the 9th Annual International Conference on Research in Computational Molecular Biology (RECOMB 2005), which was held in Cambridge, Massachusetts, on May 14-18, 2005. The RECOMB conference series was started in 1997 by Sorin Istrail, Pavel Pevzner and Michael Waterman. The list of previous meetings is shown below in the s- tion Previous RECOMB Meetings. RECOMB 2005 was hosted by the Broad Institute of MIT and Harvard, and Boston University's Center for Advanced - nomic Technology, and was excellently organized by the Organizing Committee Co-chairs Jill Mesirov and Simon Kasif. This year, 217 papers were submitted, of which the Program Committee - lected 39 for presentation at the meeting and inclusion in this proceedings. Each submission was refereed by at least three members of the Program Committee. After the completion of the referees' reports, an extensive Web-based discussion took place for making decisions. From RECOMB 2005, the Steering Committee decided to publish the proceedings as a volume of Lecture Notes in Bioinf- matics (LNBI) for which the founders of RECOMB are also the editors. The prominent volume number LNBI 3500 was assigned to this proceedings. The RECOMB conference series is closely associated with the Journal of Compu- tional Biology which traditionally publishes special issues devoted to presenting full versions of selected conference papers. The RECOMB Program Committee consistedof42members,aslistedonaseparatepage. Iwouldliketothank the RECOMB 2005 Program Committee members for their dedication and hard work.
Complex analysis --- Discrete mathematics --- Biomathematics. Biometry. Biostatistics --- Computer science --- Information systems --- Artificial intelligence. Robotics. Simulation. Graphics --- discrete wiskunde --- complexe analyse (wiskunde) --- bio-informatica --- informatica --- biometrie --- database management --- programmatielogica --- robots --- moleculaire biologie
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This volume contains the accepted full papers and extended abstracts of the 5th Brazilian Symposium on Bioinformatics held in Bu ´zios, Rio de Janeiro, Brazil from August 31 to September 3, 2010. The ?rstthree meetings ofthis series,which took place2002,2003,and 2004, were called WOB (Workshop on Bioinformatics). In 2005, the conference got its current name BSB and has since published its proceedings as a special issue of the series Lecture Notes in Bioinformatics (volumes 3594/2005, 4643/2007, 5167/2008, and 5676/2009). Its topics of interest vary in many areas of bioinformatics, including - quence analysis, motifs, and pattern matching; biomedical text mining; biolo- cal databases, data management, integration;biologicaldata mining; structural, comparative, and functional genomics; protein structure, modeling, and si- lation; gene identi?cation and regulation; gene expression analysis; gene and protein interaction and networks; molecular docking; molecular evolution and phylogenetics;computationalsystemsbiology;computationalproteomics;stat- tical analysis of molecular sequences; algorithms for problems in computational biology; as well as applications in molecular biology, biochemistry, genetics, and associated subjects. WewouldliketothankallrefereesandProgramCommitteemembersfortheir carefulworkinpreparingthis proceedingsvolume.Also,wewanttoacknowlegde the local organizers and their sta? for making this meeting possible. September 2010 Carlos E. Ferreira Satoru Miyano Peter F. Stadler Organization BSB 2010 was promoted by the Brazilian Computing Society (SBC) and was organizedbytheInformaticsDepartmentofthePontif´ ?ciaUniversidadeCat´ olica do Rio de Janeiro (PUC-Rio).
Complex analysis --- Biology --- Computer science --- Programming --- Computer architecture. Operating systems --- Information systems --- Artificial intelligence. Robotics. Simulation. Graphics --- Computer. Automation --- complexe analyse (wiskunde) --- biologie --- computers --- informatica --- programmeren (informatica) --- informatietechnologie --- algoritmen --- KI (kunstmatige intelligentie)
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Navigating safely through a wealth of genome, protein and metabolite information, as well as a host of information processing tools, without getting lost is crucial for successful research in - and teaching of - molecular biology. This concise, easy-to-follow textbook/guide serves as a valuable introduction to contemporary cell biology for readers and offers insight into the key research directions in the field. It begins with an overview of existing tools for finding, designing and investigating metabolic, genetic, signalling and other network databases. This practical guide then introduces Cell Illustrator®, a software tool for biological pathway modelling and simulation, developed by the authors. In-depth discussion reveals how this tool can be used for creating, analyzing and simulating biological models, thereby explicating and testing current understanding of basic biological processes. Readers do not require prior knowledge of differential equations or programming. Features: ¢ Provides many helpful learning aids, such as detailed examples throughout, and exercises and solutions ¢ Designed and structured to be part of a semester-long course ¢ Discusses the computational functionalities required for Systems Biology ¢ Addresses practical issues surrounding software tools ¢ Introduces the current big bio-databases such as TRANSPATH® by Biobase, and explains why and how they can be used to develop and support systems biology research ¢ Explains important pathway databases and software tools, together with their related concepts ¢ Guides the reader to model pathways in a step-by-step and clear manner ¢ Contains a Foreword written by Professor Andreas Dress, Director CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences Written for undergraduates, this reader-friendly introduction to the field of Systems Biology offers insight and teaches sound expertise in the subject. It will also prove valuable to graduate students and professionals wishing to develop and support their systems-biology research.
Histology. Cytology --- Molecular biology --- Programming --- Artificial intelligence. Robotics. Simulation. Graphics --- vormgeving --- cytologie --- simulaties --- histologie --- KI (kunstmatige intelligentie) --- moleculaire biologie
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Complex analysis --- Discrete mathematics --- Biomathematics. Biometry. Biostatistics --- Computer science --- Information systems --- Artificial intelligence. Robotics. Simulation. Graphics --- discrete wiskunde --- complexe analyse (wiskunde) --- bio-informatica --- informatica --- biometrie --- database management --- programmatielogica --- robots --- moleculaire biologie
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This book constitutes the refereed proceedings of the 7th International Symposium on Algorithms and Computation, ISAAC'96, held in Osaka, Japan, in December 1996. The 43 revised full papers were selected from a total of 119 submissions; also included are an abstract of one invited talk and a full version of a second. Among the topics covered are computational geometry, graph theory, graph algorithms, combinatorial optimization, searching and sorting, networking, scheduling, and coding and cryptology.
Computer algorithms --- Congresses --- Numerical calculations --- Data processing --- Information theory. --- Computer software. --- Computer science. --- Computer Communication Networks. --- Computer graphics. --- Computer science --- Theory of Computation. --- Algorithm Analysis and Problem Complexity. --- Computation by Abstract Devices. --- Computer Graphics. --- Computational Mathematics and Numerical Analysis. --- Mathematics. --- Computer mathematics --- Electronic data processing --- Mathematics --- Automatic drafting --- Graphic data processing --- Graphics, Computer --- Computer art --- Graphic arts --- Engineering graphics --- Image processing --- Informatics --- Science --- Software, Computer --- Computer systems --- Communication theory --- Communication --- Cybernetics --- Digital techniques
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