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A growing majority of women in the western hemisphere have been delaying initiation of childbearing to later in life. Consequently, more women in their late 30s to early 40s are attempting to get pregnant for the first time than ever before. Since the incidence of most cancers increases with age, delayed childbearing results in more female cancer survivors interested in fertility preservation. In this book, the editors provide strategies for fertility preservation in women and men who require gonadotoxic treatment. In addition, epidemiologic, ethical, medico-legal, psychologic, and social aspects of fertility preservation are discussed. Using a format that combines concise scientific background with practical methodological information and easy-to-grasp algorithms, the chapters all conform to a uniform structure, including a brief abstract, keyword glossary, step by step protocol of laboratory procedures, key issues in commentary and a list of references. The result is a unique, practical reference guide for reproductive endocrinologists, urologists, embryologists, reproductive scientists, and oncologists.

Infertility -- Diagnosis. --- Infertility -- Hormone therapy. --- Reproductive Techniques, Assisted. --- Infertility --- Reproductive health --- Human reproduction --- Persons --- Named Groups --- Men --- Women --- Medicine --- Health & Biological Sciences --- Urology & Nephrology --- Clinical Endocrinology --- Gynecology & Obstetrics --- Prevention --- Fertility, Human. --- Cancer --- Endocrine aspects. --- Cancer endocrinology --- Hormonal aspects of cancer --- Human fertility --- Natality --- Hormonal aspects --- Medicine. --- Obstetrics. --- Endocrinology. --- Urology. --- Cell biology. --- Developmental biology. --- Medicine & Public Health. --- Developmental Biology. --- Cell Biology. --- Obstetrics/Perinatology. --- Demography --- Cytology. --- Obstetrics/Perinatology/Midwifery. --- Maternal-fetal medicine --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Development (Biology) --- Growth --- Ontogeny --- Genitourinary organs --- Internal medicine --- Hormones --- Diseases --- Endocrinology .

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Gynaecologie --- Management

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Human genetics. --- Genetics, Medical --- Medical Genetics --- Anthropology, Physical --- Chromosome Disorders --- Sex Chromosome Disorders --- Genetic Diseases, Inborn --- Molecular Medicine --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology

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In recent years, the advancing science and increasing availability of assisted reproduction have given new hope to infertile couples. However, the use of IVF and ART has also led to marked increases in the number of multiple-infant live births. This poses a public health concern, as these neonates have a higher rate of pre-term delivery, compromising their survival chances and increasing their risk of lifelong disability. By optimizing the selection of gametes and embryos with high probabilities of implantation, it is possible to reduce the number of embryos transferred and, by extension, the number of high-risk multiple gestations, while maintaining or increasing pregnancy rates. Human Gametes and Preimplantation Embryos: Assessment and Diagnosis provides a broad yet concise overview of established and developing methodologies for assessment of gamete and embryo viability in assisted reproduction. This book elucidates the best practices for precisely selecting viable specimens based on morphology and cleavage rate and covers the spectrum of emerging adjunctive technologies for predicting reproductive potential. The authors present their extensive knowledge of “omics” approaches (genomics, transcriptomics, proteomics, and metabolomics), with unbiased delineation of the associated advantages and potential pitfalls. This valuable clinical resource is well suited to infertility specialists, Ob/Gyn physicians, IVF laboratory technicians, and researchers in the fields of embryology and reproductive medicine.

Gynecology. --- Human embryo -- Transplantation. --- Human reproductive technology. --- Medicine. --- Obstetrics. --- Reproductive Medicine. --- Human reproductive technology --- Infertility --- Genitalia --- Cell Physiological Processes --- Physiological Processes --- Embryo, Mammalian --- Reproductive Techniques --- Embryonic Structures --- Cell Physiological Phenomena --- Therapeutics --- Physiological Phenomena --- Urogenital System --- Anatomy --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Phenomena and Processes --- Germ Cells --- Cell Survival --- Fertilization in Vitro --- Growth and Development --- Blastocyst --- Embryo Transfer --- Reproductive Techniques, Assisted --- Medicine --- Health & Biological Sciences --- Gynecology & Obstetrics --- Treatment --- Human embryo --- Human reproduction technology. --- Transplatation. --- Embryo, Human --- Reproductive medicine. --- Medicine & Public Health. --- Obstetrics/Perinatology. --- Embryology, Human --- Obstetrics/Perinatology/Midwifery. --- Maternal-fetal medicine --- Gynaecology --- Generative organs, Female --- Human reproduction --- Human reproductive health --- Human reproductive medicine --- Reproductive medicine --- Health --- Diseases --- Health aspects --- Gynecology .

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In recent years, the advancing science and increasing availability of assisted reproduction have given new hope to infertile couples. However, the use of IVF and ART has also led to marked increases in the number of multiple-infant live births. This poses a public health concern, as these neonates have a higher rate of pre-term delivery, compromising their survival chances and increasing their risk of lifelong disability. By optimizing the selection of gametes and embryos with high probabilities of implantation, it is possible to reduce the number of embryos transferred and, by extension, the number of high-risk multiple gestations, while maintaining or increasing pregnancy rates. Human Gametes and Preimplantation Embryos: Assessment and Diagnosis provides a broad yet concise overview of established and developing methodologies for assessment of gamete and embryo viability in assisted reproduction. This book elucidates the best practices for precisely selecting viable specimens based on morphology and cleavage rate and covers the spectrum of emerging adjunctive technologies for predicting reproductive potential. The authors present their extensive knowledge of “omics” approaches (genomics, transcriptomics, proteomics, and metabolomics), with unbiased delineation of the associated advantages and potential pitfalls. This valuable clinical resource is well suited to infertility specialists, Ob/Gyn physicians, IVF laboratory technicians, and researchers in the fields of embryology and reproductive medicine.

Gynaecology. Obstetrics --- proteomics --- genomics --- zwangerschap --- obstetrie --- perinatale sterfte --- gynaecologie --- vroedkunde