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This book reviews recent breakthroughs in anti-cancer drug discovery. Building on the previous volume in the series, it outlines some of the most significant developments that have occurred in the field in the subsequent period that have led to new drug approvals or promising clinical candidates. The volume is divided into chapters that each relate to a specific protein or protein class. Each chapter provides an overview of the underlying biology and then emphasises the medicinal chemistry strategies and tactics that led to the most significant drugs and drug candidates. A summary of clinical data and the future outlook for the field is also provided. Each chapter is authored by experts in the topic and who have themselves made significant contributions to their respective fields.

Cancer --- Chemotherapy. --- Biochemistry. --- Oncology. --- Medicinal Chemistry. --- Cancer Research. --- Medical Biochemistry. --- Tumors --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Composition --- Medicinal chemistry. --- Cancer research. --- Medical biochemistry. --- Medical biochemistry --- Pathobiochemistry --- Pathological biochemistry --- Biochemistry --- Pathology --- Cancer research --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry

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Antineoplastic agents --- DNA --- Molecular biology --- Pharmacology, Experimental --- Anticancéreux --- ADN --- Biologie moléculaire --- Pharmacologie expérimentale

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DNA-Binding Proteins --- DNA-drug interactions. --- Interactions ADN-médicaments --- physiology. --- Chemistry. --- Chemistry, Organic. --- Biochemistry. --- Organic Chemistry. --- Biochemistry, general. --- Medicinal Chemistry. --- Proteins --- Amino Acids, Peptides, and Proteins --- Chemicals and Drugs --- Biochemistry --- Chemistry - General --- Chemistry --- Physical Sciences & Mathematics --- Gene Products, Protein --- Gene Proteins --- Protein Gene Products --- Proteins, Gene --- DNA Binding Protein --- DNA Single-Stranded Binding Protein --- SS DNA BP --- Single-Stranded DNA-Binding Protein --- DNA Helix Destabilizing Proteins --- Single-Stranded DNA Binding Proteins --- Binding Protein, DNA --- DNA Binding Proteins --- DNA Single Stranded Binding Protein --- DNA-Binding Protein, Single-Stranded --- Single Stranded DNA Binding Protein --- Single Stranded DNA Binding Proteins --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Organic chemistry --- Composition --- Organic chemistry. --- Medicinal chemistry. --- Biology --- Medical sciences --- Physical sciences --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry

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Descriptive organic chemistry --- Aromatic compounds --- Composés aromatiques --- 547.52 --- 547.5 --- aromaten --- organische chemie --- True aromatic compounds in general. Benzene nucleus in general --- 547.52 True aromatic compounds in general. Benzene nucleus in general --- Composés aromatiques

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