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Cancer Morbidity and mortality result from invasive and metastatic spread. Currently, no therapies are aimed at the underlying mechanisms that enable this progression due to only nascent recognition of the distinct biology which occurs only during tumor dissemination. Recent advances have highlighted the central role of cell motility during the dynamic and transient process of tumor invasion and metastasis. This book includes state-of-the-art updates by international leaders in these studies. Chapters first present the novel model systems that enable new investigations and insights. Chapters then describe in depth the key processes and molecules that may be therapeutically targeted. Finally, the role of cell motility and its signals is explored in a number of key tumor types. This compilation should be useful to researchers in basic and translational oncology as well as those developing novel agents to prevent tumor invasion and metastasis.

Metastasis. --- Cancer cells --- Motility. --- Cancer cell motility --- Motility of cancer cells --- Biomechanics --- Cancer --- Cancer metastasis --- Dissemination of cancer --- Metastases --- Metastatic cancer --- Neoplasm metastasis --- Spread of cancer --- Tumor dissemination --- Tumor metastasis --- Tumor spread --- Pathology --- Cancer invasiveness --- Cancer of unknown primary origin --- Dissemination --- Metastasis --- Oncology. --- Oncology  . --- Medicine. --- Life sciences. --- Cancer Research. --- Biomedicine general. --- Life Sciences, general. --- Biosciences --- Sciences, Life --- Science --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Physicians --- Tumors --- Health Workforce --- Cancer research. --- Biomedicine, general. --- Cancer research

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Mass communications --- Mass media --- Médias --- Social aspects --- Aspect social --- -Mass media --- -Mass communication --- Media, Mass --- Media, The --- Communication --- -Social aspects --- Médias --- -Mass communications

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Mass media --- -Mass communication --- Media, Mass --- Media, The --- Communication --- Mass media. --- -Mass media --- Mass communication

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