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This Special Issue is a collection of selected papers from the 3rd European Congress on Imaging Infection and Inflammation (www.nuclearmedicinediscovery.org/events.asp) and results of consensus sessions by major experts in the field including Nuclear Medicine physicians, Radiologists, Clinicians and microbiologists. The Journal of Clinical Medicine (JCM) provides an opportunity to publish data that were presented and discussed at the meeting in Rome in December 2019. One of the extremely important missions of this meeting was to present the recently published guidelines on diagnostic imaging of infections, and find a consensus agreement on some still controversial issues. With this in mind, the aim of the present Special Issue is to publish selected papers on: • Overviews on published guidelines • Review on recent development of diagnostic imaging of infections • Consensus document on the use of FDG and WBC in infections • Consensus document on the requirement for new radiopharmaceuticals for imaging bacteria

Medicine --- infection --- vascular graft --- multimodality imaging --- WBC scintigraphy --- FDG-PET/CT --- angio-CT --- personalized medicine --- spondylodiscitis --- spine infection --- MRI --- 18F-FDG PET/CT --- diabetic foot --- diagnosis --- FDG PET/CT --- polymeric nanoparticles --- PLGA --- optical imaging --- tumor targeting --- imaging --- [18F]FDG PET/CT --- fever of unknown origin --- FUO --- PET/CT --- 18F-FDG-PET/CT --- Infective endocarditis --- echocardiography --- computed tomography --- magnetic resonance imaging --- nuclear imaging --- positron emission tomography --- endocarditis team --- cardiac implantable electronic device --- bacteria --- radiopharmaceutical --- molecular imaging --- nuclear medicine --- prosthetic joint infection --- SPECT/CT --- radiology

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This Special Issue is a collection of selected papers from the 3rd European Congress on Imaging Infection and Inflammation (www.nuclearmedicinediscovery.org/events.asp) and results of consensus sessions by major experts in the field including Nuclear Medicine physicians, Radiologists, Clinicians and microbiologists. The Journal of Clinical Medicine (JCM) provides an opportunity to publish data that were presented and discussed at the meeting in Rome in December 2019. One of the extremely important missions of this meeting was to present the recently published guidelines on diagnostic imaging of infections, and find a consensus agreement on some still controversial issues. With this in mind, the aim of the present Special Issue is to publish selected papers on: • Overviews on published guidelines • Review on recent development of diagnostic imaging of infections • Consensus document on the use of FDG and WBC in infections • Consensus document on the requirement for new radiopharmaceuticals for imaging bacteria

infection --- vascular graft --- multimodality imaging --- WBC scintigraphy --- FDG-PET/CT --- angio-CT --- personalized medicine --- spondylodiscitis --- spine infection --- MRI --- 18F-FDG PET/CT --- diabetic foot --- diagnosis --- FDG PET/CT --- polymeric nanoparticles --- PLGA --- optical imaging --- tumor targeting --- imaging --- [18F]FDG PET/CT --- fever of unknown origin --- FUO --- PET/CT --- 18F-FDG-PET/CT --- Infective endocarditis --- echocardiography --- computed tomography --- magnetic resonance imaging --- nuclear imaging --- positron emission tomography --- endocarditis team --- cardiac implantable electronic device --- bacteria --- radiopharmaceutical --- molecular imaging --- nuclear medicine --- prosthetic joint infection --- SPECT/CT --- radiology

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The past decades have seen major developments in the understanding of the cellular and molecular biology of cancer. Significant progress has been achieved regarding long-term survival for the patients of many cancers with the use of tamoxifen for treatment of breast cancer, treatment of chronic myeloid leukaemia with imatinib, and the success of biological drugs. The transition from cytotoxic chemotherapy to targeted cancer drug discovery and development has resulted in an increasing selection of tools available to oncologists. In this Special Issue of Pharmaceuticals, we highlight the opportunities and challenges in the discovery and design of innovative cancer therapies, novel small-molecule cancer drugs and antibody–drug conjugates, with articles covering a variety of anticancer therapies and potential relevant disease states and applications. Significant efforts are being made to develop and improve cancer treatments and to translate basic research findings into clinical use, resulting in improvements in survival rates and quality of life for cancer patients. We demonstrate the possibilities and scope for future research in these areas and also highlight the challenges faced by scientists in the area of anticancer drug development leading to improved targeted treatments and better survival rates for cancer patients.

graphene oxide --- indole --- androgens --- cyclooxygenase-2 --- cyclooxygenase-1 --- heteropolysaccharide --- drug conjugation --- drug delivery --- ellipticine --- chemical linker --- oesophageal cancer --- antiproliferative activity --- topoisomerase II --- ?-lactam --- DSD --- antibody --- topoisomerase inhibitors --- magnetic targeting --- cisplatin resistance --- steroidogenesis --- [18F]FDG PET/CT --- heterocyclic chemistry --- dehydroepiandrosterone --- antimitotic --- 3-vinylazetidin-2-ones --- glioblastoma --- and cancer therapy --- intestinal mucositis --- Combretastatin A-4 --- metabolism --- anti-cancer drugs --- maghemite --- COX-1 inhibitor --- anticancer --- CYP17A1 --- conjugate and hybrid drugs --- inflammation --- snticancer drugs --- P450c17 --- tumorigenesis --- cisplatin --- biomarker profiling --- cancer drug design --- tubulin --- cytochrome P450 --- 5-fluorouracil --- prostate cancer --- abiraterone --- NCI screen --- radiation --- cancer immunotherapy --- microtubule targeted drugs --- cancer --- treatment resistance

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This reprint is related to the latest research in the field of thyroid surgery, including molecular and imaging diagnosis, surgical treatment, and the treatment of recurrent disease and advanced thyroid carcinoma.

Medicine --- Oncology --- thyroid carcinoma --- prophylactic central lymph node dissection --- lymph node metastases --- RET --- medullary thyroid carcinoma --- clinical management --- variants of uncertain significance --- differentiated thyroid cancer --- papillary thyroid cancer --- minimal extrathyroidal extension --- radioactive iodine therapy --- prognosis --- TNM --- histology --- multifocality --- lymph node metastasis --- vascular invasion --- autoimmune thyroid diseases --- radioiodine refractory --- Lenvatinib --- 18F-FDG-PET/CT --- cost-benefit analysis --- economics --- medical --- thyroid neoplasms --- radiomics --- ultrasound --- magnetic resonance imaging --- computer tomography --- prediction --- classification --- angiogenic microenvironment --- prognostic factors --- antiangiogenic therapy --- therapeutic target --- tumor microenvironment --- tumor behavior --- proliferation pathways --- cell cycle control pathways --- angiogenesis process --- thyroid cancer --- Gal-3 expression --- NIFTP --- EFVPTC --- lymphocytic thyroiditis (LT) --- immunohistochemical (IHC) analysis --- molecular imaging --- theranostics --- companion diagnostics --- immunoPET --- anaplastic thyroid cancer --- poorly thyroid cancer --- genetic landscape --- genetically guided therapy --- fluorodeoxyglucose F18 (18F-FDG) --- positron emission tomography (PET) --- magnetic resonance imaging (MRI) --- recurrence --- neoplasm metastasis --- thyroid surgery --- hypoparathyroidism --- fluorescence-guided surgery --- near-infrared autofluorescence --- PRKAR1A --- PKA --- Carney complex --- cAMP --- bone metastasis --- metastasectomy --- stereotactic radiosurgery --- ultrasound imaging --- thyroid nodule --- fine-needle aspiration --- papillary thyroid carcinoma --- lobectomy --- operative extent --- CONUT score --- tyrosine kinase inhibitors

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The aim of this book is to provide crisp information related to pathology, management and radiological/molecular imaging in breast carcinoma, along with detailed information on FDG PET-CT in breast cancer, normal variants, artefacts, pitfalls with atlas illustrations. The book is unique in providing quick reference to practice of PET/CT in breast cancer. The initial few chapters are related to the pathology and management of breast carcinoma to help understand the pathophysiology of breast cancer before going to the imaging. The chapter on imaging in breast cancer highlights the role of different imaging modalities for different indications to the reader. The last four chapters describe in detail the role, normal variants, artefacts and pitfalls of FDG PET/CT along with recent molecular imaging advances in breast cancer. Written by Pathology, Oncology, Radiology and Nuclear Medicine experts from different countries with enormous experience in breast cancer practice, the book addresses nuclear medicine physicians and radiologists, but it may be of interest to a wider medical community, including oncologists and radiotherapists. .

Breast Neoplasms --- Fluorodeoxyglucose F18 --- Positron Emission Tomography Computed Tomography. --- Molecular Imaging. --- diagnostic imaging. --- Imaging, Molecular --- CT PET --- CT PET Scan --- PET CT Scan --- PET-CT --- PET-CT Scan --- Positron Emission Tomography-Computed Tomography --- CT PET Scans --- CT Scan, PET --- CT Scans, PET --- PET CT Scans --- PET Scan, CT --- PET Scans, CT --- PET-CT Scans --- Scan, CT PET --- Scan, PET CT --- Scan, PET-CT --- Scans, CT PET --- Scans, PET CT --- Scans, PET-CT --- 18F-FDG --- Fluorine-18-fluorodeoxyglucose --- Fluorodeoxyglucose F 18 --- 18F Fluorodeoxyglucose --- 18FDG --- 2-Fluoro-2-deoxy-D-glucose --- 2-Fluoro-2-deoxyglucose --- Fludeoxyglucose F 18 --- 2 Fluoro 2 deoxy D glucose --- 2 Fluoro 2 deoxyglucose --- F 18, Fludeoxyglucose --- F 18, Fluorodeoxyglucose --- F18, Fluorodeoxyglucose --- Fluorine 18 fluorodeoxyglucose --- Fluorodeoxyglucose, 18F --- Nuclear medicine. --- Radiology. --- Oncology. --- Nuclear Medicine. --- Atomic medicine --- Radioisotopes in medicine --- Medical radiology --- Radioactive tracers --- Radioactivity --- Tumors --- Radiological physics --- Physics --- Radiation --- Physiological effect